Diazinon-oxon
Oxon of Diazinon
General
Type : Insecticide, Organophosphate, Pyrimidine
Chemical_Nomenclature : diethyl 6-methyl-2-(1-methylethyl)-4-pyrimidinyl phosphate
Canonical SMILES : CCOP(=O)(OCC)OC1=NC(=NC(=C1)C)C(C)C
InChI : InChI=1S\/C12H21N2O4P\/c1-6-16-19(15,17-7-2)18-11-8-10(5)13-12(14-11)9(3)4\/h8-9H,6-7H2,1-5H3
InChIKey : VBLJFQYCTRKKKF-UHFFFAOYSA-N
Other name(s) : diazinon oxygen analog || diazoxon || oxodiazinon || Diazinon O-analog
MW : 288.28
Formula : C12H21N2O4P
CAS_number : 962-58-3
PubChem : 13754
UniChem : VBLJFQYCTRKKKF-UHFFFAOYSA-N
Target
Families : Diazinon-oxon ligand of proteins in family
ACHE
References (12)
| Title : Relationship between acaricide resistance and acetylcholinesterase gene polymorphisms in the cattle tick Rhipicephalus microplus - Cossio-Bayugar_2024_Parasite_31_3 |
| Author(s) : Cossio-Bayugar R , Martinez-Ibanez F , Aguilar-Diaz H , Miranda-Miranda E |
| Ref : Parasite , 31 :3 , 2024 |
| Abstract : |
| PubMedSearch : Cossio-Bayugar_2024_Parasite_31_3 |
| PubMedID: 38315066 |
| Gene_locus related to this paper: boomi-ACHE2 |
| Title : Alterations in the non-neuronal cholinergic system induced by in-vitro exposure to diazoxon in spleen mononuclear cells of Nile tilapia (O. niloticus) - Toledo-Ibarra_2021_Fish.Shellfish.Immunol_108_134 |
| Author(s) : Toledo-Ibarra GA , Giron-Perez MI , Covantes-Rosales CE , Ventura-Ramon GH , Perez-Sanchez G , Lopez-Torres A , Diaz-Resendiz KJG , Becerril-Villanueva E , Pavon L |
| Ref : Fish Shellfish Immunol , 108 :134 , 2021 |
| Abstract : |
| PubMedSearch : Toledo-Ibarra_2021_Fish.Shellfish.Immunol_108_134 |
| PubMedID: 33285167 |
| Title : Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons - Pizzurro_2014_Toxicol.Appl.Pharmacol_274_372 |
| Author(s) : Pizzurro DM , Dao K , Costa LG |
| Ref : Toxicol Appl Pharmacol , 274 :372 , 2014 |
| Abstract : |
| PubMedSearch : Pizzurro_2014_Toxicol.Appl.Pharmacol_274_372 |
| PubMedID: 24342266 |
| Title : Astrocytes protect against diazinon- and diazoxon-induced inhibition of neurite outgrowth by regulating neuronal glutathione - Pizzurro_2014_Toxicology_318_59 |
| Author(s) : Pizzurro DM , Dao K , Costa LG |
| Ref : Toxicology , 318 :59 , 2014 |
| Abstract : |
| PubMedSearch : Pizzurro_2014_Toxicology_318_59 |
| PubMedID: 24561003 |
| Title : Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon - Duysen_2011_Gene.Ther_18_250 |
| Author(s) : Duysen EG , Parikh K , Aleti V , Manne V , Lockridge O , Chilukuri N |
| Ref : Gene Therapy , 18 :250 , 2011 |
| Abstract : |
| PubMedSearch : Duysen_2011_Gene.Ther_18_250 |
| PubMedID: 20981111 |
| Title : Mechanistic toxicodynamic model for receptor-mediated toxicity of diazoxon, the active metabolite of diazinon, in Daphnia magna - Kretschmann_2011_Environ.Sci.Technol_45_4980 |
| Author(s) : Kretschmann A , Ashauer R , Hitzfeld K , Spaak P , Hollender J , Escher BI |
| Ref : Environ Sci Technol , 45 :4980 , 2011 |
| Abstract : |
| PubMedSearch : Kretschmann_2011_Environ.Sci.Technol_45_4980 |
| PubMedID: 21539304 |
| Title : Effects of diazinon and diazoxon on the lymphoproliferation rate of splenocytes from Nile tilapia (Oreochromis niloticus): the immunosuppresive effect could involve an increase in acetylcholine levels - Giron-Perez_2008_Fish.Shellfish.Immunol_25_517 |
| Author(s) : Giron-Perez MI , Zaitseva G , Casas-Solis J , Santerre A |
| Ref : Fish Shellfish Immunol , 25 :517 , 2008 |
| Abstract : |
| PubMedSearch : Giron-Perez_2008_Fish.Shellfish.Immunol_25_517 |
| PubMedID: 18674623 |
| Title : Changes in mRNA and protein levels of nicotinic acetylcholine receptors in Diazoxon exposed pC12 cells - Mehrani_2008_Toxicol.In.Vitro_22_1257 |
| Author(s) : Mehrani H , Golmanesh L |
| Ref : Toxicol In Vitro , 22 :1257 , 2008 |
| Abstract : |
| PubMedSearch : Mehrani_2008_Toxicol.In.Vitro_22_1257 |
| PubMedID: 18513920 |
| Title : Fragmentations and reactions of the organophosphate insecticide Diazinon and its oxygen analog Diazoxon studied by electrospray ionization ion trap mass spectrometry - Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| Author(s) : Barr JD , Bell AJ , Bird M , Mundy JL , Murrell J , Timperley CM , Watts P , Ferrante F |
| Ref : J Am Soc Mass Spectrom , 16 :515 , 2005 |
| Abstract : |
| PubMedSearch : Barr_2005_J.Am.Soc.Mass.Spectrom_16_515 |
| PubMedID: 15792720 |
| Title : Genetic and other sources of variation in the activity of serum paraoxonase\/diazoxonase in humans: consequences for risk from exposure to diazinon - O'Leary_2005_Pharmacogenet.Genomics_15_51 |
| Author(s) : O'Leary KA , Edwards RJ , Town MM , Boobis AR |
| Ref : Pharmacogenet Genomics , 15 :51 , 2005 |
| Abstract : |
| PubMedSearch : O'Leary_2005_Pharmacogenet.Genomics_15_51 |
| PubMedID: 15864126 |
| Title : The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin - Davies_1996_Nat.Genet_14_334 |
| Author(s) : Davies HG , Richter RJ , Keifer M , Broomfield CA , Sowalla J , Furlong CE |
| Ref : Nat Genet , 14 :334 , 1996 |
| Abstract : |
| PubMedSearch : Davies_1996_Nat.Genet_14_334 |
| PubMedID: 8896566 |
| Title : Isolation and concentration of organophosphorus pesticides from drinking water at the ng\/L level, using macroreticular resin - LeBel_1979_J.Assoc.Off.Anal.Chem_62_241 |
| Author(s) : LeBel GL , Williams DT , Griffith G , Benoit FM |
| Ref : J Assoc Off Analytical Chemistry , 62 :241 , 1979 |
| Abstract : |
| PubMedSearch : LeBel_1979_J.Assoc.Off.Anal.Chem_62_241 |
| PubMedID: 447594 |