Duysen EG

General

Full name : Duysen Ellen G

First name : Ellen G

Mail : University of Nebraska\; Medical Center\; Omaha\; NE 68198-6805

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Country : USA

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References (56)

Title : Study of acetylcholinesterase activity and apoptosis in SH-SY5Y cells and mice exposed to ethanol - Sun_2017_Toxicology_384_33
Author(s) : Sun W , Chen L , Zheng W , Wei X , Wu W , Duysen EG , Jiang W
Ref : Toxicology , 384 :33 , 2017
PubMedID: 28427893

Title : Polyclonal antibody to soman-tyrosine - Li_2013_Chem.Res.Toxicol_26_584
Author(s) : Li B , Duysen EG , Froment MT , Masson P , Nachon F , Jiang W , Schopfer LM , Thiele GM , Klassen LW , Cashman JR , Williams GR , Lockridge O
Ref : Chemical Research in Toxicology , 26 :584 , 2013
PubMedID: 23469927

Title : Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry - Jiang_2012_Toxicology_295_15
Author(s) : Jiang W , Duysen EG , Lockridge O
Ref : Toxicology , 295 :15 , 2012
PubMedID: 22406659

Title : Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran - Duysen_2012_Chem.Biol.Interact_195_189
Author(s) : Duysen EG , Cashman JR , Schopfer LM , Nachon F , Masson P , Lockridge O
Ref : Chemico-Biological Interactions , 195 :189 , 2012
PubMedID: 22209767

Title : Role of acetylcholinesterase on the structure and function of cholinergic synapses: insights gained from studies on knockout mice - Adler_2011_Cell.Mol.Neurobiol_31_909
Author(s) : Adler M , Sweeney RE , Hamilton TA , Lockridge O , Duysen EG , Purcell AL , Deshpande SS
Ref : Cellular Molecular Neurobiology , 31 :909 , 2011
PubMedID: 21538119

Title : Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon - Duysen_2011_Gene.Ther_18_250
Author(s) : Duysen EG , Parikh K , Aleti V , Manne V , Lockridge O , Chilukuri N
Ref : Gene Therapy , 18 :250 , 2011
PubMedID: 20981111

Title : Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons - Duysen_2011_Toxicol.Appl.Pharmacol_255_214
Author(s) : Duysen EG , Lockridge O
Ref : Toxicol Appl Pharmacol , 255 :214 , 2011
PubMedID: 21767560

Title : Prolonged toxic effects after cocaine challenge in butyrylcholinesterase\/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans - Duysen_2011_Drug.Metab.Dispos_39_1321
Author(s) : Duysen EG , Lockridge O
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 39 :1321 , 2011
PubMedID: 21540357

Title : Gene-Delivered Butyrylcholinesterase Is Prophylactic against the Toxicity of Chemical Warfare Nerve Agents and Organophosphorus Compounds - Parikh_2011_J.Pharmacol.Exp.Ther_337_92
Author(s) : Parikh K , Duysen EG , Snow B , Jensen NS , Manne V , Lockridge O , Chilukuri N
Ref : Journal of Pharmacology & Experimental Therapeutics , 337 :92 , 2011
PubMedID: 21205915

Title : Production of ES1 plasma carboxylesterase knockout mice for toxicity studies - Duysen_2011_Chem.Res.Toxicol_24_1891
Author(s) : Duysen EG , Koentgen F , Williams GR , Timperley CM , Schopfer LM , Cerasoli DM , Lockridge O
Ref : Chemical Research in Toxicology , 24 :1891 , 2011
PubMedID: 21875074
Gene_locus related to this paper: mouse-Ces1c

Title : Contributions of selective knockout studies to understanding cholinesterase disposition and function - Camp_2010_Chem.Biol.Interact_187_72
Author(s) : Camp S , Zhang L , Krejci E , Dobbertin A , Bernard V , Girard E , Duysen EG , Lockridge O , De Jaco A , Taylor P
Ref : Chemico-Biological Interactions , 187 :72 , 2010
PubMedID: 20153304

Title : Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse - Hrabovska_2010_Chem.Biol.Interact_183_194
Author(s) : Hrabovska A , Farar V , Bernard V , Duysen EG , Brabec J , Lockridge O , Myslivecek J
Ref : Chemico-Biological Interactions , 183 :194 , 2010
PubMedID: 19818744

Title : Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents - Jiang_2010_Toxicol.Sci_115_183
Author(s) : Jiang W , Duysen EG , Hansen H , Shlyakhtenko L , Schopfer LM , Lockridge O
Ref : Toxicol Sci , 115 :183 , 2010
PubMedID: 20142434

Title : Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice - Naik_2009_J.Pharm.Pharm.Sci_12_79
Author(s) : Naik RS , Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J
Ref : J Pharm Pharm Sci , 12 :79 , 2009
PubMedID: 19470293

Title : The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease - Duysen_2009_Expert.Opin.Drug.Metab.Toxicol_5_523
Author(s) : Duysen EG , Li B , Lockridge O
Ref : Expert Opin Drug Metab Toxicol , 5 :523 , 2009
PubMedID: 19416087

Title : Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents - Chilukuri_2009_Mol.Pharmacol_76_612
Author(s) : Chilukuri N , Duysen EG , Parikh K , diTargiani RC , Doctor BP , Lockridge O , Saxena A
Ref : Molecular Pharmacology , 76 :612 , 2009
PubMedID: 19542320

Title : Mass spectrometry identifies multiple organophosphorylated sites on tubulin - Grigoryan_2009_Toxicol.Appl.Pharmacol_240_149
Author(s) : Grigoryan H , Schopfer LM , Peeples ES , Duysen EG , Grigoryan M , Thompson CM , Lockridge O
Ref : Toxicol Appl Pharmacol , 240 :149 , 2009
PubMedID: 19632257

Title : Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: visualization and quantification of enzyme distribution in the brain - Johnson_2009_Neurotoxicol_30_386
Author(s) : Johnson ND , Duysen EG , Lockridge O
Ref : Neurotoxicology , 30 :386 , 2009
PubMedID: 19442823

Title : Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice - Hartmann_2008_Neurochem.Int_52_972
Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Klein J
Ref : Neurochem Int , 52 :972 , 2008
PubMedID: 18023504

Title : The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency - Li_2008_J.Pharmacol.Exp.Ther_324_1146
Author(s) : Li B , Duysen EG , Carlson M , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :1146 , 2008
PubMedID: 18056867

Title : The butyrylcholinesterase knockout mouse is obese on a high-fat diet - Li_2008_Chem.Biol.Interact_175_88
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Chemico-Biological Interactions , 175 :88 , 2008
PubMedID: 18452903

Title : Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo - Chilukuri_2008_Chem.Biol.Interact_175_327
Author(s) : Chilukuri N , Duysen EG , Parikh K , Sun W , Doctor BP , Lockridge O , Saxena A
Ref : Chemico-Biological Interactions , 175 :327 , 2008
PubMedID: 18499092

Title : Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice - Duysen_2008_Basic.Clin.Pharmacol.Toxicol_103_514
Author(s) : Duysen EG , Li B , Carlson M , Li YF , Wieseler S , Hinrichs SH , Lockridge O
Ref : Basic Clin Pharmacol Toxicol , 103 :514 , 2008
PubMedID: 19067679

Title : Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase - Duysen_2008_Chem.Biol.Interact_175_119
Author(s) : Duysen EG , Lockridge O
Ref : Chemico-Biological Interactions , 175 :119 , 2008
PubMedID: 18486120

Title : Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity - Hartmann_2007_J.Neurochem_100_1421
Author(s) : Hartmann J , Kiewert C , Duysen EG , Lockridge O , Greig NH , Klein J
Ref : Journal of Neurochemistry , 100 :1421 , 2007
PubMedID: 17212694

Title : Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease - Rice_2007_J.Alzheimers.Dis_11_481
Author(s) : Rice SG , Nowak L , Duysen EG , Lockridge O , Lahiri DK , Reyes PF
Ref : J Alzheimers Dis , 11 :481 , 2007
PubMedID: 17656828

Title : Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission - Duysen_2007_Toxicology_233_60
Author(s) : Duysen EG , Li B , Darvesh S , Lockridge O
Ref : Toxicology , 233 :60 , 2007
PubMedID: 17194517

Title : Adaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout mice - Myslivecek_2007_Naunyn.Schmiedebergs.Arch.Pharmacol_376_83
Author(s) : Myslivecek J , Duysen EG , Lockridge O
Ref : Naunyn Schmiedebergs Arch Pharmacol , 376 :83 , 2007
PubMedID: 17805515

Title : Phenotype comparison of three acetylcholinesterase knockout strains - Duysen_2006_J.Mol.Neurosci_30_91
Author(s) : Duysen EG , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :91 , 2006
PubMedID: 17192642

Title : Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase - Li_2006_Toxicol.Appl.Pharmacol_214_152
Author(s) : Li B , Duysen EG , Poluektova LY , Murrin LC , Lockridge O
Ref : Toxicol Appl Pharmacol , 214 :152 , 2006
PubMedID: 16443250

Title : Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP - Li_2006_J.Mol.Neurosci_30_79
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :79 , 2006
PubMedID: 17192637

Title : Production of the butyrylcholinesterase knockout mouse - Li_2006_J.Mol.Neurosci_30_193
Author(s) : Li B , Duysen EG , Saunders TL , Lockridge O
Ref : Journal of Molecular Neuroscience , 30 :193 , 2006
PubMedID: 17192674

Title : Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma - Li_2005_Biochem.Pharmacol_70_1673
Author(s) : Li B , Sedlacek M , Manoharan I , Boopathy R , Duysen EG , Masson P , Lockridge O
Ref : Biochemical Pharmacology , 70 :1673 , 2005
PubMedID: 16213467

Title : Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry - Peeples_2005_Toxicol.Sci_83_303
Author(s) : Peeples ES , Schopfer LM , Duysen EG , Spaulding R , Voelker T , Thompson CM , Lockridge O
Ref : Toxicol Sci , 83 :303 , 2005
PubMedID: 15525694

Title : Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice - Lockridge_2005_Environ.Toxicol.Pharmacol_19_463
Author(s) : Lockridge O , Duysen EG , Voelker T , Thompson CM , Schopfer LM
Ref : Environ Toxicol Pharmacol , 19 :463 , 2005
PubMedID: 21783513

Title : Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse - Hrabovska_2005_Chem.Biol.Interact_157-158_71
Author(s) : Hrabovska A , Duysen EG , Sanders JD , Murrin LC , Lockridge O
Ref : Chemico-Biological Interactions , 157-158 :71 , 2005
PubMedID: 16243306

Title : Poster (78) H. hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension. -
Author(s) : Duysen EG , Kolar CH , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :362 , 2004
PubMedID:

Title : Phenotype of the adult acetylcholinesterase-deficient mouse. -
Author(s) : Duysen EG , Stribley JA , Fry DL , Hinrichs SH , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :559 , 2004
PubMedID:

Title : Poster (90) Acetylcholinesterase knockout mice are resistant oxotremorine-induced hypothermia and pilocarpine-induced seizures -
Author(s) : Li B , Duysen EG , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :368 , 2004
PubMedID:

Title : Acetylcholinesterase knockout mice have increased sensitivity to scopolamine and atropine. -
Author(s) : Hrabovska A , Duysen EG , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :593 , 2004
PubMedID:

Title : Muscarinic acetylcholine receptors are down-regulated in acetylcholinesterase knockout mice. -
Author(s) : Li B , Duysen EG , Lockridge O
Ref : Cholinergic Mechanisms, CRC Press :619 , 2004
PubMedID:

Title : Helicobacter hepaticus infection in acetylcholinesterase knockout mice results in severe intestinal distension -
Author(s) : Duysen EG , Kolar CH , Lockridge O
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :301 , 2004
PubMedID:

Title : Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase - Wang_2004_Toxicol.Appl.Pharmacol_196_356
Author(s) : Wang Y , Boeck AT , Duysen EG , Van Keuren M , Saunders TL , Lockridge O
Ref : Toxicol Appl Pharmacol , 196 :356 , 2004
PubMedID: 15094306

Title : Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants - Wang_2004_Anal.Biochem_329_131
Author(s) : Wang Y , Schopfer LM , Duysen EG , Nachon F , Masson P , Lockridge O
Ref : Analytical Biochemistry , 329 :131 , 2004
PubMedID: 15136175

Title : Poster (55) Life without acetylcholinesterase -
Author(s) : Lockridge O , Duysen EG , Li B , Hrabovska A
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :350 , 2004
PubMedID:

Title : Poster (59) Complete postnatal degeneration of the photoreceptor layer in an AChE knockout mouse -
Author(s) : Bytyqi AH , Duysen EG , Lockridge O , Layer PG
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :352 , 2004
PubMedID:

Title : Poster (60) Early distortion of network formation in the inner retina of an AChE knockout mouse -
Author(s) : Bytyqi AH , Paraoanu LE , Duysen EG , Lockridge O , Layer PG
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :353 , 2004
PubMedID:

Title : Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice - Adler_2004_Muscle.Nerve_30_317
Author(s) : Adler M , Manley HA , Purcell AL , Deshpande SS , Hamilton TA , Kan RK , Oyler G , Lockridge O , Duysen EG , Sheridan RE
Ref : Muscle & Nerve , 30 :317 , 2004
PubMedID: 15318343

Title : Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice - Li_2003_Pharmacol.Biochem.Behav_74_977
Author(s) : Li B , Duysen EG , Volpicelli-Daley LA , Levey AI , Lockridge O
Ref : Pharmacol Biochem Behav , 74 :977 , 2003
PubMedID: 12667913

Title : Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice - Volpicelli-Daley_2003_Ann.Neurol_53_788
Author(s) : Volpicelli-Daley LA , Duysen EG , Lockridge O , Levey AI
Ref : Annals of Neurology , 53 :788 , 2003
PubMedID: 12783426

Title : Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice - Volpicelli-Daley_2003_Mol.Pharmacol_64_1309
Author(s) : Volpicelli-Daley LA , Hrabovska A , Duysen EG , Ferguson SM , Blakely RD , Lockridge O , Levey AI
Ref : Molecular Pharmacology , 64 :1309 , 2003
PubMedID: 14645660

Title : Early weaning and culling eradicated Helicobacter hepaticus from an acetylcholinesterase knockout 129S6\/SvEvTac mouse colony - Duysen_2002_Comp.Med_52_461
Author(s) : Duysen EG , Fry DL , Lockridge O
Ref : Comp Med , 52 :461 , 2002
PubMedID: 12405641

Title : Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine - Mesulam_2002_Neurosci_110_627
Author(s) : Mesulam MM , Guillozet A , Shaw P , Levey AI , Duysen EG , Lockridge O , Levey A
Ref : Neuroscience , 110 :627 , 2002
PubMedID: 11934471

Title : Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity - Duysen_2002_J.Pharmacol.Exp.Ther_302_751
Author(s) : Duysen EG , Bartels CF , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :751 , 2002
PubMedID: 12130740

Title : Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet\; phenotype of the adult acetylcholinesterase deficient mouse - Duysen_2002_Brain.Res.Dev.Brain.Res_137_43
Author(s) : Duysen EG , Stribley JA , Fry DL , Hinrichs SH , Lockridge O
Ref : Brain Research Developmental Brain Research , 137 :43 , 2002
PubMedID: 12128253

Title : Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to vx lethality - Duysen_2001_J.Pharmacol.Exp.Ther_299_528
Author(s) : Duysen EG , Li B , Xie W , Schopfer LM , Anderson RS , Broomfield CA , Lockridge O
Ref : Journal of Pharmacology & Experimental Therapeutics , 299 :528 , 2001
PubMedID: 11602663