Ethacridine
General
Type : Acridine, Derivative of Tacrine
Chemical_Nomenclature : 7-ethoxyacridine-3,9-diamine || 7-ethoxyacridine-3,9-diamine\;2-hydroxypropanoic acid
Canonical SMILES : CCOC1=CC2=C(C3=C(C=C(C=C3)N)N=C2C=C1)N
InChI : InChI=1S\/C15H15N3O\/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13\/h3-8H,2,16H2,1H3,(H2,17,18)
InChIKey : CIKWKGFPFXJVGW-UHFFFAOYSA-N
Other name(s) : 6,9-Diamino-2-ethoxyacridine || Aethacridinum || Etacridina || RefChem:138010 || SCHEMBL193949 || SCHEMBL27823685 || SCHEMBL29456272 || SCHEMBL30310148 || CHEBI:135032 || Ethacridine lactate || acrinol || Rivanol || 6,9-Diamino-2-ethoxyacridine lactate
MW : 253.3
Formula : C15H15N3O
CAS_number : 442-16-0, 1837-57-6
UniChem : CIKWKGFPFXJVGW-UHFFFAOYSA-N
Target
References (9)
| Title : Acridine: A Scaffold for the development of drugs for Alzheimer's disease - Sharma_2023_Curr.Top.Med.Chem__ |
| Author(s) : Sharma A , Piplani P |
| Ref : Curr Top Med Chem , : , 2023 |
| Abstract : |
| PubMedSearch : Sharma_2023_Curr.Top.Med.Chem__ |
| PubMedID: 36740790 |
| Title : Acridine: A Scaffold for the development of drugs for Alzheimer's disease - Sharma_2023_Curr.Top.Med.Chem__ |
| Author(s) : Sharma A , Piplani P |
| Ref : Curr Top Med Chem , : , 2023 |
| Abstract : |
| PubMedSearch : Sharma_2023_Curr.Top.Med.Chem__ |
| PubMedID: 36740790 |
| Title : Acridine: A Scaffold for the development of drugs for Alzheimer's disease - Sharma_2023_Curr.Top.Med.Chem__ |
| Author(s) : Sharma A , Piplani P |
| Ref : Curr Top Med Chem , : , 2023 |
| Abstract : |
| PubMedSearch : Sharma_2023_Curr.Top.Med.Chem__ |
| PubMedID: 36740790 |
| Title : Analysis of enzyme activity regulation by non-denaturing electrophoresis and application of this regulation for enzyme reactor production - Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| Author(s) : Shimazaki Y , Miki S |
| Ref : J Enzyme Inhib Med Chem , 28 :894 , 2013 |
| Abstract : |
| PubMedSearch : Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| PubMedID: 22803677 |
| Title : Analysis of enzyme activity regulation by non-denaturing electrophoresis and application of this regulation for enzyme reactor production - Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| Author(s) : Shimazaki Y , Miki S |
| Ref : J Enzyme Inhib Med Chem , 28 :894 , 2013 |
| Abstract : |
| PubMedSearch : Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| PubMedID: 22803677 |
| Title : Analysis of enzyme activity regulation by non-denaturing electrophoresis and application of this regulation for enzyme reactor production - Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| Author(s) : Shimazaki Y , Miki S |
| Ref : J Enzyme Inhib Med Chem , 28 :894 , 2013 |
| Abstract : |
| PubMedSearch : Shimazaki_2013_J.Enzyme.Inhib.Med.Chem_28_894 |
| PubMedID: 22803677 |
| Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
| Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
| Ref : Chemical Biology , 10 :341 , 2003 |
| Abstract : |
| PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
| PubMedID: 12725862 |
| Gene_locus related to this paper: human-CES1 |
| Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
| Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
| Ref : Chemical Biology , 10 :341 , 2003 |
| Abstract : |
| PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
| PubMedID: 12725862 |
| Gene_locus related to this paper: human-CES1 |
| Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341 |
| Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR |
| Ref : Chemical Biology , 10 :341 , 2003 |
| Abstract : |
| PubMedSearch : Bencharit_2003_Chem.Biol_10_341 |
| PubMedID: 12725862 |
| Gene_locus related to this paper: human-CES1 |