GL-B437
General
Type : Urea derivative, Adamantyl, Piperidine, Carboxamide
Chemical_Nomenclature : 1-[4-[[(3S,5S)-3,5-dimethyl-1-adamantyl]carbamoylamino]-3-fluorobenzoyl]piperidine-3-carboxamide
Canonical SMILES : C[C@]12CC3C[C@@](C1)(CC(C3)(C2)NC(=O)NC4=C(C=C(C=C4)C(=O)N5CCCC(C5)C(=O)N)F)C
InChI : InChI=1S\/C26H35FN4O3\/c1-24-9-16-10-25(2,13-24)15-26(11-16,14-24)30-23(34)29-20-6-5-17(8-19(20)27)22(33)31-7-3-4-18(12-31)21(28)32\/h5-6,8,16,18H,3-4,7,9-15H2,1-2H3,(H2,28,32)(H2,29,30,34)\/t16?,18?,24-,25-,26?\/m0\/s1
InChIKey : MHFVCLGMODRMJX-QOHCPSDKSA-N
Other name(s) :
MW : 470.6
Formula : C26H35FN4O3
CAS_number :
PubChem : 156780920, 156780889
UniChem : MHFVCLGMODRMJX-QOHCPSDKSA-N
Target
Families : GL-B437 ligand of proteins in family
Epoxide_hydrolase
Protein :
human-EPHX2
References (1)
| Title : Design and Synthesis of sEH\/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain - Xu_2024_J.Med.Chem__ |
| Author(s) : Xu H , Chen Y , Tong H , Chen L , Morisseau C , Zhou Z , Zhuang J , Song C , Cai P , Liu Z , Hammock BD , Chen G |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Xu_2024_J.Med.Chem__ |
| PubMedID: 39033411 |