Adamantyl

General

Fusion of three cyclohexane rings, found naturally in petroleum. It is an element of many drugs memantine, saxagliptin, vildagliptin

Inhibitor	Main targeted enzyme familyes	Type
sEH-HDAC6-IN-M9	Epoxide_hydrolase	Multitarget Adamantyl Urea derivative
Rivastigmine-Donepezil-COR783		Cannabinoid-Receptor-ligand Derivative of Rivastigmine Multitarget Sulfur Compound Derivative of Donepezil Carbamate Adamantyl
Amiridine-Admantyl-5d		Quinoline Derivative of Tacrine Derivative of Amiridine Derivative of Adamantyl NMDA-Ligand
Adamantyl-urea-Cpd28	Epoxide_hydrolase	Adamantyl Urea derivative Indole
Amantadine-M30D-hybrid5e	BCHE	Monoamine-oxidase-inhibitor Multitarget Carbamate Adamantyl Alkyl linked bis-ligand
HyT13	Haloalkane_dehalogenase-HLD2	Adamantyl
CHEMBL3402240-4A0-4Y2X	Epoxide_hydrolase	Adamantyl
CS38	Palmitoyl-protein_thioesterase	Adamantyl Triazol Benzoate Sulfur Compound
UB-EV-52	Epoxide_hydrolase	Adamantyl Urea derivative
CHEMBL1818384	Epoxide_hydrolase	Adamantyl Urea derivative
t-AUCB	Epoxide_hydrolase	Adamantyl Urea derivative
nbAUDA	Epoxide_hydrolase	Adamantyl Urea derivative Dodecanoate Laurate
CHEMBL3633668	Epoxide_hydrolase	Urea derivative Adamantyl
5ALU-HD2	Epoxide_hydrolase	Adamantyl Urea derivative Carboxamide Pyrimidine Not A\/B H target
5ALZ-XQ9	Epoxide_hydrolase	Urea derivative Adamantyl Piperidine Sulfur Compound Sulfonyl Sulfonamide
AEPU	Epoxide_hydrolase	Adamantyl Urea derivative
AUDA	Epoxide_hydrolase	Adamantyl Dodecanoate Urea derivative
N-1-adamantyl-N'-cyclohexylurea	Epoxide_hydrolase	Adamantyl Urea derivative
ARN14140-doubleboundlink	ACHE	Adamantyl Alkyl linked bis-ligand Multitarget Derivative of Galanthamine NMDA-Ligand Azepine
ARN14140	ACHE	Adamantyl Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand
benzohomoadamantane-chlorotacrine-18a	ACHE	Multitarget NMDA-Ligand Adamantyl Derivative of Tacrine
benzohomoadamantane-chlorotacrine-18b	BCHE ACHE	Multitarget NMDA-Ligand Adamantyl Derivative of Tacrine Alkyl linked bis-ligand
triazole-aryl-adamantane-Cpd32	ACHE	Multitarget NMDA-Ligand Adamantyl Triazol
7-methoxytacrine-memantine-Cpd4	ACHE	Multitarget NMDA-Ligand Adamantyl Urea derivative Alkyl linked bis-ligand Sulfur Compound Derivative of Tacrine
NMDA-BCHE-C-2h	BCHE	Multitarget NMDA-Ligand Carbazol Adamantyl
Adamantyl-ebselen	A85-Mycolyl-transferase	Adamantyl Organoselenium Thiol-reactive
B401	Epoxide_hydrolase	Urea derivative Adamantyl Piperidine
Ar9281	Epoxide_hydrolase	Adamantyl Urea derivative
t-AUCMB	Epoxide_hydrolase	Urea derivative Multitarget Adamantyl
Saxagliptin	DPP4N_Peptidase_S9	Adamantyl Drug Cyanide Pyrrolidine Gliptin Azabicyclo
VildaSaxagliptin-analogue	DPP4N_Peptidase_S9	Pyrrolidine Gliptin Adamantyl Azabicyclo
Indol-adamantyl-carbamate-Cpd42	DPP4N_Peptidase_S9	Gliptin Adamantyl Carbamate Indole
Indol-adamantyl-carbamate-Nitrobenzooxadiazol-Cpd20	DPP4N_Peptidase_S9	Gliptin Adamantyl Carbamate Indole Oxadiazol NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
Vildagliptin	DPP4N_Peptidase_S9	Drug Pyrrolidine Gliptin Adamantyl