Methyl-demeton
This substance is a mixture of many individual substances and cannot be adequately represented by a single molecular structure. || Demeton (Demeton-s-methyl)mecaptophos Trade names for products containing demeton-s-methyl include Meta-Systox I, Meta-isosystox, Azotox, Bay-18436, Bay-25/154, DSM, Duratox, Metasystox 55, Mifatox, and Persyst
General
Type : Insecticide, Organophosphate, Sulfur Compound, Organothiophosphate
Chemical_Nomenclature : 1-dimethoxyphosphorylsulfanyl-2-ethylsulfanylethane\;2-ethylsulfanylethoxy-dimethoxy-sulfanylidene-$l^{5}-phosphane
Canonical SMILES : CCSCCOP(=S)(OC)OC.CCSCCSP(=O)(OC)OC || CCS(=O)CCSP(=O)(OC)OC
InChI : InChI=1S\/2C6H15O3PS2\/c1-4-11-5-6-12-10(7,8-2)9-3\;1-4-12-6-5-9-10(11,7-2)8-3\/h2*4-6H2,1-3H3 || InChI=1S\/C6H15O4PS2\/c1-4-13(8)6-5-12-11(7,9-2)10-3\/h4-6H2,1-3H3
InChIKey : KPNPDRFFWQBXGT-UHFFFAOYSA-N || PMCVMORKVPSKHZ-UHFFFAOYSA-N
Other name(s) : Phosphorothioic acid O-[2-(ethylthio)ethyl]O,O-dimethyl ester mix with S-[2-(ethylthio)ethyl]O,O-dimethyl Phosphorothioate || oxydemeton methyl || oxydemeton-methyl || Metasystox || demeton-methyl || demeton-S-methyl || Duratox || bay 15203 || bayer 21\/116 || Phosphorothioic acid S-[2-(ethylsulfinyl)ethyl] O,O-dimethyl ester || S-(2-(Ethylsulfinyl)ethyl) O,O-dimethyl ester phosphorothioic acid || Metasystox R || Metasystox-R || bay 21097 || bayer 21097 || demeton-o-methyl sulfoxide || demeton-s-methyl sulfoxide || demeton-methyl sulfoxide || R2170 || Dylox\/MSR || Inject-A-Cide || Harpoon
MW : 460.6 || 246.3
Formula : C12H30O6P2S4 || C6H15O3PS2 || C6H15O4PS2
CAS_number : 8022-00-2, 301-12-2
UniChem : KPNPDRFFWQBXGT-UHFFFAOYSA-N, PMCVMORKVPSKHZ-UHFFFAOYSA-N
Target
Families : Methyl-demeton ligand of proteins in family
ACHE
References (11)
| Title : Inhibition with simultaneous spontaneous reactivation and aging of acetylcholinesterase by organophosphorus compounds: Demeton-S-methyl as a model - Estevez_2023_Chem.Biol.Interact_14ChEPon_110789 |
| Author(s) : Estevez J , Pizarro L , Marsillach J , Furlong C , Sogorb MA , Richter R , Vilanova E |
| Ref : Chemico-Biological Interactions , :110789 , 2023 |
| Abstract : |
| PubMedSearch : Estevez_2023_Chem.Biol.Interact_14ChEPon_110789 |
| PubMedID: 37931869 |
| Title : Organophosphate Level Evaluation for the Poisoning Treatment by Enzyme Activation Regeneration Strategy with Oxime-Functionalized ZIF-8 Nanoparticles - Shen_2023_Anal.Chem__ |
| Author(s) : Shen A , Hao X , Li M , Zhao Y , Li Z , Hou L , Duan R , Zhang P , Zhang L , Yang Y |
| Ref : Analytical Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Shen_2023_Anal.Chem__ |
| PubMedID: 37358141 |
| Title : The kinetic study of the inhibition of human cholinesterases by demeton-S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate - Bazire_2011_Toxicol.In.Vitro_25_754 |
| Author(s) : Bazire A , Gillon E , Lockridge O , Vallet V , Nachon F |
| Ref : Toxicol In Vitro , 25 :754 , 2011 |
| Abstract : |
| PubMedSearch : Bazire_2011_Toxicol.In.Vitro_25_754 |
| PubMedID: 21238577 |
| Title : Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX - Ghanem_2007_Biochemistry_46_9032 |
| Author(s) : Ghanem E , Li Y , Xu C , Raushel FM |
| Ref : Biochemistry , 46 :9032 , 2007 |
| Abstract : |
| PubMedSearch : Ghanem_2007_Biochemistry_46_9032 |
| PubMedID: 17630782 |
| Title : Reductive cleavage of demeton-S-methyl by Corynebacterium glutamicum in cometabolism on more readily metabolizable substrates - Girbal_2000_Appl.Environ.Microbiol_66_1202 |
| Author(s) : Girbal L , Hilaire D , Leduc S , Delery L , Rols JL , Lindley ND |
| Ref : Applied Environmental Microbiology , 66 :1202 , 2000 |
| Abstract : |
| PubMedSearch : Girbal_2000_Appl.Environ.Microbiol_66_1202 |
| PubMedID: 10698792 |
| Title : Severe organophosphate (demeton-S-methyl) poisoning in a two-year-old child - Rolfsjord_1998_Vet.Hum.Toxicol_40_222 |
| Author(s) : Rolfsjord LB , Fjaerli HO , Meidel N , Stromme JH , Kowalczyk M , Jacobsen D |
| Ref : Vet Hum Toxicol , 40 :222 , 1998 |
| Abstract : |
| PubMedSearch : Rolfsjord_1998_Vet.Hum.Toxicol_40_222 |
| PubMedID: 9682409 |
| Title : The relationship between maternal and fetal effects following maternal organophosphate exposure during gestation in the rat - Astroff_1998_Toxicol.Ind.Health_14_869 |
| Author(s) : Astroff AB , Young AD |
| Ref : Toxicol Ind Health , 14 :869 , 1998 |
| Abstract : |
| PubMedSearch : Astroff_1998_Toxicol.Ind.Health_14_869 |
| PubMedID: 9891917 |
| Title : Risk factors for systemic illnesses following agricultural exposures to restricted organophosphates in California, 1984-1988 - Weinbaum_1997_Am.J.Ind.Med_31_572 |
| Author(s) : Weinbaum Z , Schenker MB , Gold EB , Samuels SJ , O'Malley MA |
| Ref : American Journal of Industrial Medicine , 31 :572 , 1997 |
| Abstract : |
| PubMedSearch : Weinbaum_1997_Am.J.Ind.Med_31_572 |
| PubMedID: 9099360 |
| Title : Biochemical and histological effects of the aphicide demeton-S-methyl on house sparrows (Passer domesticus) under field conditions - |
| Author(s) : Tarrant KA , Thompson HM , Hardy AR |
| Ref : Bulletin of Environmental Contamination & Toxicology , 48 :360 , 1992 |
| PubMedID: 1627909 |
| Title : Teratological, neurochemical, and postnatal neurobehavioral assessment of METASYSTOX-R, an organophosphate pesticide in the rat - Clemens_1990_Fundam.Appl.Toxicol_14_131 |
| Author(s) : Clemens GR , Hartnagel RE , Bare JJ , Thyssen JH |
| Ref : Fundamental & Applied Toxicology , 14 :131 , 1990 |
| Abstract : |
| PubMedSearch : Clemens_1990_Fundam.Appl.Toxicol_14_131 |
| PubMedID: 2307312 |
| Title : Sister-chromatid exchanges and cell-cycle delay in Chinese hamster V79 cells treated with 9 organophosphorus compounds (8 pesticides and 1 defoliant) - Chen_1982_Mutat.Res_103_307 |
| Author(s) : Chen HH , Sirianni SR , Huang CC |
| Ref : Mutat Res , 103 :307 , 1982 |
| Abstract : |
| PubMedSearch : Chen_1982_Mutat.Res_103_307 |
| PubMedID: 6211614 |