Propoxur
Insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy
General
Type : Carbamate, Insecticide
Chemical_Nomenclature : o Isopropoxyphenyl Methyl Carbamate\; 2-(1-Methylethoxy)phenol methylcarbamate
Canonical SMILES : CC(C)OC1=CC=CC=C1OC(=O)NC
InChI : InChI=1S\/C11H15NO3\/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3\/h4-8H,1-3H3,(H,12,13)
InChIKey : ISRUGXGCCGIOQO-UHFFFAOYSA-N
Other name(s) : aprocarb, Baygon, BAY 39007, BAY 9010, Blattanex, Suncide, Unden, Blattosep, Bolfo, Chemagro 9010, DMS 33, IMPC, Invisi-gard, Isocarb, Pillargon, Propotox, Propyon, Sendran, Tendex, Tugon, fliegenkugel
MW : 209.25
Formula : C11H15NO3
CAS_number : 114-26-1
PubChem : 4944
UniChem : ISRUGXGCCGIOQO-UHFFFAOYSA-N
Wikipedia : Propoxur
References (15)
| Title : Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur - Padilla_2007_Toxicol.Appl.Pharmacol_219_202 |
| Author(s) : Padilla S , Marshall RS , Hunter DL , Lowit A |
| Ref : Toxicol Appl Pharmacol , 219 :202 , 2007 |
| PubMedID: 17197007 |
| Title : Evaluation of insecticide resistance and biochemical mechanisms in a population of culex quinquefasciatus (Diptera: Culicidae) from Sao Paulo, Brazil - Bracco_1999_Mem.Inst.Oswaldo.Cruz_94_115 |
| Author(s) : Bracco JE , Barata JM , Marinotti O |
| Ref : Mem Inst Oswaldo Cruz , 94 :115 , 1999 |
| PubMedID: 10029921 |
| Title : Resistance to organophosphorus and pyrethroid insecticides in Culex pipiens (Diptera: Culicidae) from Tunisia - Ben Cheikh_1998_J.Med.Entomol_35_251 |
| Author(s) : Ben Cheikh H , Ben Ali-Haouas Z , Marquine M , Pasteur N |
| Ref : Journal of Medical Entomology , 35 :251 , 1998 |
| PubMedID: 9615543 |
| Title : [Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de Cuba] - Rodriguez_1997_Rev.Cubana.Med.Trop_49_209 |
| Author(s) : Rodriguez MM , Bisset J , Rodriguez I , Diaz C |
| Ref : Rev Cubana Med Trop , 49 :209 , 1997 |
| PubMedID: 9685989 |
| Title : Distribution of organophosphate and carbamate resistance in Culex pipiens quinquefasciatus (Diptera: Culicidae) in West Africa - Chandre_1997_J.Med.Entomol_34_664 |
| Author(s) : Chandre F , Darriet F , Doannio JM , Riviere F , Pasteur N , Guillet P |
| Ref : Journal of Medical Entomology , 34 :664 , 1997 |
| PubMedID: 9439121 |
| Title : Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides - Klotz_1997_Life.Sci_60_1467 |
| Author(s) : Klotz DM , Arnold SF , McLachlan JA |
| Ref : Life Sciences , 60 :1467 , 1997 |
| PubMedID: 9126867 |
| Title : Organophosphate resistance in Culex pipiens from Cyprus - Wirth_1996_J.Am.Mosq.Control.Assoc_12_112 |
| Author(s) : Wirth MC , Georghiou GP |
| Ref : J Am Mosq Control Assoc , 12 :112 , 1996 |
| PubMedID: 8723267 |
| Title : Characterization of resistance to organophosphate, carbamate, and pyrethroid insecticides in field populations of Aedes aegypti from Venezuela - Mazzarri_1995_J.Am.Mosq.Control.Assoc_11_315 |
| Author(s) : Mazzarri MB , Georghiou GP |
| Ref : J Am Mosq Control Assoc , 11 :315 , 1995 |
| PubMedID: 8551300 |
| Title : Anopheles culicifacies in Baluchistan, Iran - Zaim_1995_Med.Vet.Entomol_9_181 |
| Author(s) : Zaim M , Manouchehri AV , Motabar M , Emadi AM , Nazari M , Pakdad K , Kayedi MH , Mowlaii G |
| Ref : Med Vet Entomol , 9 :181 , 1995 |
| PubMedID: 7787227 |
| Title : Ketamine protects acetylcholinesterase against inhibition by propoxur and phoxim - Koutsoviti-Papadopoulou_1994_Pharmacol.Res_30_117 |
| Author(s) : Koutsoviti-Papadopoulou M , Kounenis G , Elezoglou V |
| Ref : Pharmacol Res , 30 :117 , 1994 |
| PubMedID: 7816740 |
| Title : Insecticide susceptibility status & enzyme profile of Aedes albopictus populations from different localities of Maharashtra state - Chakraborti_1993_Indian.J.Med.Res_97_37 |
| Author(s) : Chakraborti S , Mourya DT , Gokhale MD , Banerjee K |
| Ref : Indian J Med Res , 97 :37 , 1993 |
| PubMedID: 8486408 |
| Title : Relative inhibition of rat plasma and erythrocyte cholinesterases by pesticide combinations - Iyaniwura_1991_Vet.Hum.Toxicol_33_166 |
| Author(s) : Iyaniwura TT |
| Ref : Vet Hum Toxicol , 33 :166 , 1991 |
| PubMedID: 2035247 |
| Title : Single-mosquito test to determine genotypes with an acetylcholinesterase insensitive to inhibition to propoxur insecticide - Raymond_1985_J.Am.Mosquito.Control.Assoc_1_425 |
| Author(s) : Raymond M , Fournier D , Berge JB , Cuany A , Bride JM , Pasteur N |
| Ref : Journal of the American Mosquito Control Association , 1 :425 , 1985 |
| PubMedID: 3880259 |
| Title : Residual toxicity of wall-sprayed organophosphates, carbamates and pyrethroids to mosquito Culex pipiens molestus Forskal - Rettich_1980_J.Hyg.Epidemiol.Microbiol.Immunol_24_110 |
| Author(s) : Rettich F |
| Ref : J Hyg Epidemiol Microbiol Immunol , 24 :110 , 1980 |
| PubMedID: 7190586 |
| Title : [Radiometric determination of 11 carbamate pesticides in the nanogram and subnanongram ranges by means of cholinesterase inhibition] - Schmid_1977_Nahrung_21_311 |
| Author(s) : Schmid ER , Damboritz W , Markl P |
| Ref : Nahrung , 21 :311 , 1977 |
| PubMedID: 406567 |