Propoxur

Insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy

General

Type : Carbamate, Insecticide

Chemical_Nomenclature : o Isopropoxyphenyl Methyl Carbamate\; 2-(1-Methylethoxy)phenol methylcarbamate

Canonical SMILES : CC(C)OC1=CC=CC=C1OC(=O)NC

InChI : InChI=1S\/C11H15NO3\/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3\/h4-8H,1-3H3,(H,12,13)

InChIKey : ISRUGXGCCGIOQO-UHFFFAOYSA-N

Other name(s) : aprocarb  ||  Baygon  ||  BAY 39007  ||  BAY 9010  ||  Blattanex  ||  Suncide  ||  Unden  ||  Blattosep  ||  Bolfo  ||  Chemagro 9010  ||  DMS 33  ||  IMPC  ||  Invisi-gard  ||  Isocarb  ||  Pillargon  ||  Propotox  ||  Propyon  ||  Sendran  ||  Tendex  ||  Tugon  ||  fliegenkugel


MW : 209.25

Formula : C11H15NO3

CAS_number : 114-26-1

PubChem : 4944

UniChem : ISRUGXGCCGIOQO-UHFFFAOYSA-N

Wikipedia : Propoxur

Target

Families : Propoxur ligand of proteins in family
ACHE BCHE

References (15)

Title : Time course of cholinesterase inhibition in adult rats treated acutely with carbaryl, carbofuran, formetanate, methomyl, methiocarb, oxamyl or propoxur - Padilla_2007_Toxicol.Appl.Pharmacol_219_202
Author(s) : Padilla S , Marshall RS , Hunter DL , Lowit A
Ref : Toxicol Appl Pharmacol , 219 :202 , 2007
Abstract :
PubMedSearch : Padilla_2007_Toxicol.Appl.Pharmacol_219_202
PubMedID: 17197007

Title : Evaluation of insecticide resistance and biochemical mechanisms in a population of culex quinquefasciatus (Diptera: Culicidae) from Sao Paulo, Brazil - Bracco_1999_Mem.Inst.Oswaldo.Cruz_94_115
Author(s) : Bracco JE , Barata JM , Marinotti O
Ref : Mem Inst Oswaldo Cruz , 94 :115 , 1999
Abstract :
PubMedSearch : Bracco_1999_Mem.Inst.Oswaldo.Cruz_94_115
PubMedID: 10029921

Title : Resistance to organophosphorus and pyrethroid insecticides in Culex pipiens (Diptera: Culicidae) from Tunisia - Ben Cheikh_1998_J.Med.Entomol_35_251
Author(s) : Ben Cheikh H , Ben Ali-Haouas Z , Marquine M , Pasteur N
Ref : Journal of Medical Entomology , 35 :251 , 1998
Abstract :
PubMedSearch : Ben Cheikh_1998_J.Med.Entomol_35_251
PubMedID: 9615543

Title : [Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de Cuba] - Rodriguez_1997_Rev.Cubana.Med.Trop_49_209
Author(s) : Rodriguez MM , Bisset J , Rodriguez I , Diaz C
Ref : Rev Cubana Med Trop , 49 :209 , 1997
Abstract :
PubMedSearch : Rodriguez_1997_Rev.Cubana.Med.Trop_49_209
PubMedID: 9685989

Title : Distribution of organophosphate and carbamate resistance in Culex pipiens quinquefasciatus (Diptera: Culicidae) in West Africa - Chandre_1997_J.Med.Entomol_34_664
Author(s) : Chandre F , Darriet F , Doannio JM , Riviere F , Pasteur N , Guillet P
Ref : Journal of Medical Entomology , 34 :664 , 1997
Abstract :
PubMedSearch : Chandre_1997_J.Med.Entomol_34_664
PubMedID: 9439121

Title : Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides - Klotz_1997_Life.Sci_60_1467
Author(s) : Klotz DM , Arnold SF , McLachlan JA
Ref : Life Sciences , 60 :1467 , 1997
Abstract :
PubMedSearch : Klotz_1997_Life.Sci_60_1467
PubMedID: 9126867

Title : Organophosphate resistance in Culex pipiens from Cyprus - Wirth_1996_J.Am.Mosq.Control.Assoc_12_112
Author(s) : Wirth MC , Georghiou GP
Ref : J Am Mosq Control Assoc , 12 :112 , 1996
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PubMedSearch : Wirth_1996_J.Am.Mosq.Control.Assoc_12_112
PubMedID: 8723267

Title : Anopheles culicifacies in Baluchistan, Iran - Zaim_1995_Med.Vet.Entomol_9_181
Author(s) : Zaim M , Manouchehri AV , Motabar M , Emadi AM , Nazari M , Pakdad K , Kayedi MH , Mowlaii G
Ref : Med Vet Entomol , 9 :181 , 1995
Abstract :
PubMedSearch : Zaim_1995_Med.Vet.Entomol_9_181
PubMedID: 7787227

Title : Characterization of resistance to organophosphate, carbamate, and pyrethroid insecticides in field populations of Aedes aegypti from Venezuela - Mazzarri_1995_J.Am.Mosq.Control.Assoc_11_315
Author(s) : Mazzarri MB , Georghiou GP
Ref : J Am Mosq Control Assoc , 11 :315 , 1995
Abstract :
PubMedSearch : Mazzarri_1995_J.Am.Mosq.Control.Assoc_11_315
PubMedID: 8551300

Title : Ketamine protects acetylcholinesterase against inhibition by propoxur and phoxim - Koutsoviti-Papadopoulou_1994_Pharmacol.Res_30_117
Author(s) : Koutsoviti-Papadopoulou M , Kounenis G , Elezoglou V
Ref : Pharmacol Res , 30 :117 , 1994
Abstract :
PubMedSearch : Koutsoviti-Papadopoulou_1994_Pharmacol.Res_30_117
PubMedID: 7816740

Title : Insecticide susceptibility status & enzyme profile of Aedes albopictus populations from different localities of Maharashtra state - Chakraborti_1993_Indian.J.Med.Res_97_37
Author(s) : Chakraborti S , Mourya DT , Gokhale MD , Banerjee K
Ref : Indian J Med Res , 97 :37 , 1993
Abstract :
PubMedSearch : Chakraborti_1993_Indian.J.Med.Res_97_37
PubMedID: 8486408

Title : Relative inhibition of rat plasma and erythrocyte cholinesterases by pesticide combinations - Iyaniwura_1991_Vet.Hum.Toxicol_33_166
Author(s) : Iyaniwura TT
Ref : Vet Hum Toxicol , 33 :166 , 1991
Abstract :
PubMedSearch : Iyaniwura_1991_Vet.Hum.Toxicol_33_166
PubMedID: 2035247

Title : Single-mosquito test to determine genotypes with an acetylcholinesterase insensitive to inhibition to propoxur insecticide - Raymond_1985_J.Am.Mosquito.Control.Assoc_1_425
Author(s) : Raymond M , Fournier D , Berge JB , Cuany A , Bride JM , Pasteur N
Ref : Journal of the American Mosquito Control Association , 1 :425 , 1985
Abstract :
PubMedSearch : Raymond_1985_J.Am.Mosquito.Control.Assoc_1_425
PubMedID: 3880259

Title : Residual toxicity of wall-sprayed organophosphates, carbamates and pyrethroids to mosquito Culex pipiens molestus Forskal - Rettich_1980_J.Hyg.Epidemiol.Microbiol.Immunol_24_110
Author(s) : Rettich F
Ref : J Hyg Epidemiol Microbiol Immunol , 24 :110 , 1980
Abstract :
PubMedSearch : Rettich_1980_J.Hyg.Epidemiol.Microbiol.Immunol_24_110
PubMedID: 7190586

Title : [Radiometric determination of 11 carbamate pesticides in the nanogram and subnanongram ranges by means of cholinesterase inhibition] - Schmid_1977_Nahrung_21_311
Author(s) : Schmid ER , Damboritz W , Markl P
Ref : Nahrung , 21 :311 , 1977
Abstract :
PubMedSearch : Schmid_1977_Nahrung_21_311
PubMedID: 406567