Resveratrol-thieno-oxazole-Cpd14
hBChE with IC50 values of 0.248 microM
General
Type : Carbamate, Carboxylate, Sulfur Compound, Multitarget, Antioxidant, Thiophen, Pyrrolidine, Oxazole, Derivative of Resveratrol
Chemical_Nomenclature : 2-[(1E)-2-[5-(1,3-oxazol-5-yl)thiophen-2-yl]ethenyl]phenyl pyrrolidine-1-carboxylate
Canonical SMILES : C1=C(C(=CC=C1)C=CC2=CC=C(S2)C3=CN=CO3)OC(=O)N4CCCC4
InChI : InChI=1S\/C20H18N2O3S\/c23-20(22-11-3-4-12-22)25-17-6-2-1-5-15(17)7-8-16-9-10-19(26-16)18-13-21-14-24-18\/h1-2,5-10,13-14H,3-4,11-12H2
InChIKey : AUGQZIFTXAGWMC-UHFFFAOYSA-N
Other name(s) : Compound 14 || o-[(E)-2-[5-(1,3-Oxazol-5-yl)-2-thienyl]ethenyl]phenyl 1-pyrrolidinecarboxylate || (E)-2-(2-(5-(oxazol-5-yl)thiophen-2-yl)vinyl)phenyl pyrrolidine-1-carboxylate
Target
Families : Resveratrol-thieno-oxazole-Cpd14 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Novel resveratrol-inspired thieno-benzimidazoles and thieno-oxazoles - Synthesis, selective butyrylcholinesterase inhibition and molecular modeling - Mlakic_2026_Bioorg.Chem_180_110096 |
| Author(s) : Mlakic M , Talic S , Odak I , Roca S , Sagud I , Baric D , Skoric I |
| Ref : Bioorg Chem , 180 :110096 , 2026 |
| Abstract : |
| PubMedSearch : Mlakic_2026_Bioorg.Chem_180_110096 |
| PubMedID: 42330851 |