TPAU
General
Type : Trifluoro, Piperidine, Urea derivative
Chemical_Nomenclature : 1-(1-acetylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea
Canonical SMILES : CC(=O)N1CCC(CC1)NC(=O)NC2=CC=C(C=C2)OC(F)(F)F
InChI : InChI=1S\/C15H18F3N3O3\/c1-10(22)21-8-6-12(7-9-21)20-14(23)19-11-2-4-13(5-3-11)24-15(16,17)18\/h2-5,12H,6-9H2,1H3,(H2,19,20,23)
InChIKey : UAKAZEQUWPXSOS-UHFFFAOYSA-N
Other name(s) : 3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]urea || 1-trifluoromethoxyphenyl-3-(1-acetylpiperidin-4-yl) urea || Urea-based compound, 25 || SCHEMBL5143669 || sEHi, #1555
MW : 345.32
Formula : C15H18F3N3O3
CAS_number :
PubChem : 25093352
UniChem : UAKAZEQUWPXSOS-UHFFFAOYSA-N
Target
References (6)
| Title : Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice - Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| Author(s) : Inceoglu AB , Clifton HL , Yang J , Hegedus C , Hammock BD , Schaefer S |
| Ref : J Cardiovasc Pharmacol , 60 :70 , 2012 |
| Abstract : |
| PubMedSearch : Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| PubMedID: 22526297 |
| Title : Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice - Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| Author(s) : Inceoglu AB , Clifton HL , Yang J , Hegedus C , Hammock BD , Schaefer S |
| Ref : J Cardiovasc Pharmacol , 60 :70 , 2012 |
| Abstract : |
| PubMedSearch : Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| PubMedID: 22526297 |
| Title : Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys - Ulu_2012_Br.J.Pharmacol_165_1401 |
| Author(s) : Ulu A , Appt S , Morisseau C , Hwang SH , Jones PD , Rose TE , Dong H , Lango J , Yang J , Tsai HJ , Miyabe C , Fortenbach C , Adams MR , Hammock BD |
| Ref : British Journal of Pharmacology , 165 :1401 , 2012 |
| Abstract : |
| PubMedSearch : Ulu_2012_Br.J.Pharmacol_165_1401 |
| PubMedID: 21880036 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys - Ulu_2012_Br.J.Pharmacol_165_1401 |
| Author(s) : Ulu A , Appt S , Morisseau C , Hwang SH , Jones PD , Rose TE , Dong H , Lango J , Yang J , Tsai HJ , Miyabe C , Fortenbach C , Adams MR , Hammock BD |
| Ref : British Journal of Pharmacology , 165 :1401 , 2012 |
| Abstract : |
| PubMedSearch : Ulu_2012_Br.J.Pharmacol_165_1401 |
| PubMedID: 21880036 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice - Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| Author(s) : Inceoglu AB , Clifton HL , Yang J , Hegedus C , Hammock BD , Schaefer S |
| Ref : J Cardiovasc Pharmacol , 60 :70 , 2012 |
| Abstract : |
| PubMedSearch : Inceoglu_2012_J.Cardiovasc.Pharmacol_60_70 |
| PubMedID: 22526297 |
| Title : Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys - Ulu_2012_Br.J.Pharmacol_165_1401 |
| Author(s) : Ulu A , Appt S , Morisseau C , Hwang SH , Jones PD , Rose TE , Dong H , Lango J , Yang J , Tsai HJ , Miyabe C , Fortenbach C , Adams MR , Hammock BD |
| Ref : British Journal of Pharmacology , 165 :1401 , 2012 |
| Abstract : |
| PubMedSearch : Ulu_2012_Br.J.Pharmacol_165_1401 |
| PubMedID: 21880036 |
| Gene_locus related to this paper: human-EPHX2 |