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Inhibitor Report for: C14-palmitoyl-MAG-like-phosphonate

mimics the Monoacylglycerol MAG of identical size (here the 1-palmitoylglycerol Monopalmitin (C16:0)). The adduct on the active serine lacks the leaving group 4-nitrophenol


General
Type Organophosphate, pNP, Lipase inhibitor, Analogue of substrate, Azido
Chemical_Nomenclature 3-[hydroxy(tetradecoxy)phosphoryl]propylimino-iminoazanium
Canonical SMILES CCCCCCCCCCCCCCOP(=O)(CCCN=[N+]=N)O
InChI InChI=1S/C17H36N3O3P/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-23-24(21,22)17-14-15-19-20-18/h18H,2-17H2,1H3/p+1
InChIKey DBFCYRAMTWKWQC-UHFFFAOYSA-O
Other name(s) Tetradecyl Hydrogen (R)-(3-Azidopropyl)phosphonate ; 1QY
________________________________________________________________________________________________
MW|362.47
Formula|C17H37N3O3P+
CAS_number|
PubChem|71710908
UniChem|DBFCYRAMTWKWQC-UHFFFAOYSA-O
IUPHAR|
Wikipedia|

Target
Families | C14-palmitoyl-MAG-like-phosphonate ligand of proteins in family: CarbLipBact_2
Stucture | 1 structure: 4KE8: Crystal structure of monoacylglycerol lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue
Protein | bac25-mglp

References:
Search PubMed for references concerning: C14-palmitoyl-MAG-like-phosphonate
    Title: Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase
    Rengachari S, Aschauer P, Schittmayer M, Mayer N, Gruber K, Breinbauer R, Birner-Gruenberger R, Dreveny I, Oberer M
    Ref: Journal of Biological Chemistry, 288:31093, 2013 : PubMed