F297I_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Oxime interaction Cochran_2011_J.Biol.Chem_286_29718

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Oxime interaction

Torpedo_number : 290

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.F297I Phe297Ile (p.F328I Phe328Ile in primary sequence with 31 amino-acids signal peptide) Oxime interaction

References (1)

Title : Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging - Cochran_2011_J.Biol.Chem_286_29718
Author(s) : Cochran R , Kalisiak J , Kucukkilinc TT , Radic Z , Garcia E , Zhang L , Ho KY , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :29718 , 2011
PubMedID: 21730071