Fokin VV

References (14)

Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100
Author(s) : Kovarik Z , Kalisiak J , Hrvat NM , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemistry , 25 :4100 , 2019
PubMedID: 30458057

Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40
Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Toxicol Appl Pharmacol , 372 :40 , 2019
PubMedID: 30978400
Gene_locus related to this paper: human-ACHE

Title : Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure - Sit_2018_J.Pharmacol.Exp.Ther_367_363
Author(s) : Sit RK , Kovarik Z , Macek Hrvat N , Zunec S , Green C , Fokin VV , Sharpless KB , Radic Z , Taylor P
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :363 , 2018
PubMedID: 30190337

Title : Cognitive Improvements in a Mouse Model with Substituted 1,2,3-Triazole Agonists for Nicotinic Acetylcholine Receptors - Arunrungvichian_2015_ACS.Chem.Neurosci_6_1331
Author(s) : Arunrungvichian K , Boonyarat C , Fokin VV , Taylor P , Vajragupta O
Ref : ACS Chem Neurosci , 6 :1331 , 2015
PubMedID: 25978789

Title : Catalytic Soman Scavenging by the Y337A\/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes - Kovarik_2015_Chem.Res.Toxicol_28_1036
Author(s) : Kovarik Z , Macek Hrvat N , Katalinic M , Sit RK , Paradyse A , Zunec S , Musilek K , Fokin VV , Taylor P , Radic Z
Ref : Chemical Research in Toxicology , 28 :1036 , 2015
PubMedID: 25835984

Title : Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification - Sit_2014_J.Med.Chem_57_1378
Author(s) : Sit RK , Fokin VV , Amitai G , Sharpless KB , Taylor P , Radic Z
Ref : Journal of Medicinal Chemistry , 57 :1378 , 2014
PubMedID: 24571195

Title : Centrally acting oximes in reactivation of tabun-phosphoramidated AChE - Kovarik_2013_Chem.Biol.Interact_203_77
Author(s) : Kovarik Z , Macek Hrvat N , Sit RK , Radic Z , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :77 , 2013
PubMedID: 22960624

Title : Mechanism of interaction of novel uncharged, centrally active reactivators with OP-hAChE conjugates - Radic_2013_Chem.Biol.Interact_203_67
Author(s) : Radic Z , Sit RK , Garcia E , Zhang LM , Zunec S , Kovarik Z , Amitai G , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 203 :67 , 2013
PubMedID: 22975155

Title : Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases - Radic_2012_J.Biol.Chem_287_11798
Author(s) : Radic Z , Sit RK , Kovarik Z , Zunec S , Garcia E , Zhang L , Amitai G , Green C , Radic B , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 287 :11798 , 2012
PubMedID: 22343626

Title : Synthesis of selective agonists for the alpha7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates - Yamauchi_2012_Mol.Pharmacol_82_687
Author(s) : Yamauchi JG , Gomez K , Grimster N , Dufouil M , Nemecz A , Fotsing JR , Ho KY , Talley TT , Sharpless KB , Fokin VV , Taylor P
Ref : Molecular Pharmacology , 82 :687 , 2012
PubMedID: 22784805

Title : Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template - Grimster_2012_J.Am.Chem.Soc_134_6732
Author(s) : Grimster NP , Stump B , Fotsing JR , Weide T , Talley TT , Yamauchi JG , Nemecz A , Kim C , Ho KY , Sharpless KB , Taylor P , Fokin VV
Ref : Journal of the American Chemical Society , 134 :6732 , 2012
PubMedID: 22394239

Title : New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases - Sit_2011_J.Biol.Chem_286_19422
Author(s) : Sit RK , Radic Z , Gerardi V , Zhang L , Garcia E , Katalinic M , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :19422 , 2011
PubMedID: 21464125

Title : Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging - Cochran_2011_J.Biol.Chem_286_29718
Author(s) : Cochran R , Kalisiak J , Kucukkilinc TT , Radic Z , Garcia E , Zhang L , Ho KY , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P
Ref : Journal of Biological Chemistry , 286 :29718 , 2011
PubMedID: 21730071

Title : Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase - Radic_2010_Chem.Biol.Interact_187_163
Author(s) : Radic Z , Kalisiak J , Fokin VV , Sharpless KB , Taylor P
Ref : Chemico-Biological Interactions , 187 :163 , 2010
PubMedID: 20412789