| Title : Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase - Kovarik_2019_Toxicol.Appl.Pharmacol_372_40 |
| Author(s) : Kovarik Z , Macek Hrvat N , Kalisiak J , Katalinic M , Sit RK , Zorbaz T , Radic Z , Fokin VV , Sharpless KB , Taylor P |
| Ref : Toxicol Appl Pharmacol , 372 :40 , 2019 |
| Abstract : |
| PubMedSearch : Kovarik_2019_Toxicol.Appl.Pharmacol_372_40 |
| PubMedID: 30978400 |
| Gene_locus related to this paper: human-ACHE |
| Title : Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases - Macek Hrvat_2019_Toxicol.Lett_321_83 |
| Author(s) : Macek Hrvat N , Kalisiak J , Sinko G , Radic Z , Sharpless KB , Taylor P , Kovarik Z |
| Ref : Toxicol Lett , 321 :83 , 2019 |
| Abstract : |
| PubMedSearch : Macek Hrvat_2019_Toxicol.Lett_321_83 |
| PubMedID: 31863869 |
| Title : Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase - Kovarik_2019_Chemistry_25_4100 |
| Author(s) : Kovarik Z , Kalisiak J , Macek Hrvat N , Katalinic M , Zorbaz T , Zunec S , Green C , Radic Z , Fokin VV , Sharpless KB , Taylor P |
| Ref : Chemistry , 25 :4100 , 2019 |
| Abstract : |
| PubMedSearch : Kovarik_2019_Chemistry_25_4100 |
| PubMedID: 30458057 |
| Title : Nonquaternary reactivators for organophosphate-inhibited cholinesterases - Kalisiak_2012_J.Med.Chem_55_465 |
| Author(s) : Kalisiak J , Ralph EC , Cashman JR |
| Ref : Journal of Medicinal Chemistry , 55 :465 , 2012 |
| Abstract : |
| PubMedSearch : Kalisiak_2012_J.Med.Chem_55_465 |
| PubMedID: 22206546 |
| Title : Amidine-oximes: reactivators for organophosphate exposure - Kalisiak_2011_J.Med.Chem_54_3319 |
| Author(s) : Kalisiak J , Ralph EC , Zhang J , Cashman JR |
| Ref : Journal of Medicinal Chemistry , 54 :3319 , 2011 |
| Abstract : |
| PubMedSearch : Kalisiak_2011_J.Med.Chem_54_3319 |
| PubMedID: 21438612 |
| Title : Oxime-assisted acetylcholinesterase catalytic scavengers of organophosphates that resist aging - Cochran_2011_J.Biol.Chem_286_29718 |
| Author(s) : Cochran R , Kalisiak J , Tuylu Kucukkilinc T , Radic Z , Garcia E , Zhang L , Ho KY , Amitai G , Kovarik Z , Fokin VV , Sharpless KB , Taylor P |
| Ref : Journal of Biological Chemistry , 286 :29718 , 2011 |
| Abstract : |
| PubMedSearch : Cochran_2011_J.Biol.Chem_286_29718 |
| PubMedID: 21730071 |
| Title : Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase - Radic_2010_Chem.Biol.Interact_187_163 |
| Author(s) : Radic Z , Kalisiak J , Fokin VV , Sharpless KB , Taylor P |
| Ref : Chemico-Biological Interactions , 187 :163 , 2010 |
| Abstract : |
| PubMedSearch : Radic_2010_Chem.Biol.Interact_187_163 |
| PubMedID: 20412789 |
| Title : Investigating the structural influence of surface mutations on acetylcholinesterase inhibition by organophosphorus compounds and oxime reactivation - Kucukkilinc_2010_Chem.Biol.Interact_187_238 |
| Author(s) : Tuylu Kucukkilinc T , Cochran R , Kalisiak J , Garcia E , Valle A , Amitai G , Radic Z , Taylor P |
| Ref : Chemico-Biological Interactions , 187 :238 , 2010 |
| Abstract : |
| PubMedSearch : Kucukkilinc_2010_Chem.Biol.Interact_187_238 |
| PubMedID: 20382137 |