Coleman_2009_PLoS.Genet_5_E1000618

Reference

Title : The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion - Coleman_2009_PLoS.Genet_5_e1000618
Author(s) : Coleman JJ , Rounsley SD , Rodriguez-Carres M , Kuo A , Wasmann CC , Grimwood J , Schmutz J , Taga M , White GJ , Zhou S , Schwartz DC , Freitag M , Ma LJ , Danchin EG , Henrissat B , Coutinho PM , Nelson DR , Straney D , Napoli CA , Barker BM , Gribskov M , Rep M , Kroken S , Molnar I , Rensing C , Kennell JC , Zamora J , Farman ML , Selker EU , Salamov A , Shapiro H , Pangilinan J , Lindquist E , Lamers C , Grigoriev IV , Geiser DM , Covert SF , Temporini E , Vanetten HD
Ref : PLoS Genet , 5 :e1000618 , 2009
Abstract :

The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of >50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on >100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches.

PubMedSearch : Coleman_2009_PLoS.Genet_5_e1000618
PubMedID: 19714214
Gene_locus related to this paper: fusso-cutas , nech7-c7yh18 , nech7-c7yir8 , nech7-c7yiz6 , nech7-c7yjl4 , nech7-c7yjp7 , nech7-c7yjq0 , nech7-c7ymg9 , nech7-c7ymv6 , nech7-c7yna5 , nech7-c7ynt6 , nech7-c7yq59 , nech7-c7yq86 , nech7-c7yqb0 , nech7-c7yqx3 , nech7-c7ysz7 , nech7-c7ysz8 , nech7-c7ytb2 , nech7-c7yum7 , nech7-c7yvb1 , nech7-c7yvb8 , nech7-c7yvf1 , nech7-c7yvq8 , nech7-c7yw21 , nech7-c7yx47 , nech7-c7yx92 , nech7-c7yxe7 , nech7-c7yxq5 , nech7-c7yxz4 , nech7-c7yy47 , nech7-c7yyj7 , nech7-c7yym7 , nech7-c7z0d7 , nech7-c7z0s1 , nech7-c7z1g9 , nech7-c7z1k9 , nech7-c7z2k4 , nech7-c7z2m9 , nech7-c7z2z2 , nech7-c7z3z3 , nech7-c7z4a4 , nech7-c7z5n1 , nech7-c7z5y2 , nech7-c7z6g5 , nech7-c7z7d0 , nech7-c7z7w8 , nech7-c7z8q7 , nech7-c7z9e7 , nech7-c7z073 , nech7-c7z354 , nech7-c7z389 , nech7-c7z688 , nech7-c7z855 , nech7-c7z987 , nech7-c7za94 , nech7-c7zah0 , nech7-c7zb79 , nech7-c7zbr8 , nech7-c7zcd1 , nech7-c7zdx8 , nech7-c7ze42 , nech7-c7ze84 , nech7-c7zed8 , nech7-c7zeh0 , nech7-c7zes2 , nech7-c7zgw2 , nech7-c7zha0 , nech7-c7zhy2 , nech7-c7zi55 , nech7-c7zig4 , nech7-c7zjg0 , nech7-c7zjv2 , nech7-c7zk96 , nech7-c7zkb5 , nech7-c7zkh4 , nech7-c7zla9 , nech7-c7zld2 , nech7-c7zlz1 , nech7-c7zm00 , nech7-c7zmn4 , nech7-c7zmu6 , nech7-c7zp06 , nech7-c7zp78 , nech7-c7zq58 , nech7-c7zq86 , nech7-c7zqb5 , nech7-c7zqk4 , nech7-c7zqp9 , nech7-c7zr59 , nech7-c7zrh2 , nech7-c7zrh3 , nech7-dapb , nech7-kex1 , nech7-c7zgl9 , nech7-c7z935 , nech7-c7znc0 , nech7-c7yiq8 , nech7-c7yiq7 , nech7-c7zhu0 , nech7-c7yw61 , nech7-c7yqd3 , nech7-c7zkb6 , nech7-c7z3b4 , nech7-c7ytr4 , nech7-c7zgf7 , 9hypo-a0a3m2s2j6 , nech7-c7yq54 , fusv7-cbpya

Related information

Gene_locus fusso-cutas    nech7-c7yh18    nech7-c7yir8    nech7-c7yiz6    nech7-c7yjl4    nech7-c7yjp7    nech7-c7yjq0    nech7-c7ymg9    nech7-c7ymv6    nech7-c7yna5    nech7-c7ynt6    nech7-c7yq59    nech7-c7yq86    nech7-c7yqb0    nech7-c7yqx3    nech7-c7ysz7    nech7-c7ysz8    nech7-c7ytb2    nech7-c7yum7    nech7-c7yvb1    nech7-c7yvb8    nech7-c7yvf1    nech7-c7yvq8    nech7-c7yw21    nech7-c7yx47    nech7-c7yx92    nech7-c7yxe7    nech7-c7yxq5    nech7-c7yxz4    nech7-c7yy47    nech7-c7yyj7    nech7-c7yym7    nech7-c7z0d7    nech7-c7z0s1    nech7-c7z1g9    nech7-c7z1k9    nech7-c7z2k4    nech7-c7z2m9    nech7-c7z2z2    nech7-c7z3z3    nech7-c7z4a4    nech7-c7z5n1    nech7-c7z5y2    nech7-c7z6g5    nech7-c7z7d0    nech7-c7z7w8    nech7-c7z8q7    nech7-c7z9e7    nech7-c7z073    nech7-c7z354    nech7-c7z389    nech7-c7z688    nech7-c7z855    nech7-c7z987    nech7-c7za94    nech7-c7zah0    nech7-c7zb79    nech7-c7zbr8    nech7-c7zcd1    nech7-c7zdx8    nech7-c7ze42    nech7-c7ze84    nech7-c7zed8    nech7-c7zeh0    nech7-c7zes2    nech7-c7zgw2    nech7-c7zha0    nech7-c7zhy2    nech7-c7zi55    nech7-c7zig4    nech7-c7zjg0    nech7-c7zjv2    nech7-c7zk96    nech7-c7zkb5    nech7-c7zkh4    nech7-c7zla9    nech7-c7zld2    nech7-c7zlz1    nech7-c7zm00    nech7-c7zmn4    nech7-c7zmu6    nech7-c7zp06    nech7-c7zp78    nech7-c7zq58    nech7-c7zq86    nech7-c7zqb5    nech7-c7zqk4    nech7-c7zqp9    nech7-c7zr59    nech7-c7zrh2    nech7-c7zrh3    nech7-dapb    nech7-kex1    nech7-c7zgl9    nech7-c7z935    nech7-c7znc0    nech7-c7yiq8    nech7-c7yiq7    nech7-c7zhu0    nech7-c7yw61    nech7-c7yqd3    nech7-c7zkb6    nech7-c7z3b4    nech7-c7ytr4    nech7-c7zgf7    9hypo-a0a3m2s2j6    nech7-c7yq54    fusv7-cbpya
Gene_locus_frgt nech7-c7z8v9    nech7-c7zdx1    nech7-c7ze21    nech7-c7zh47    nech7-c7zhl8    nech7-c7zka8    nech7-c7z7n5

Citations formats

Coleman JJ, Rounsley SD, Rodriguez-Carres M, Kuo A, Wasmann CC, Grimwood J, Schmutz J, Taga M, White GJ, Zhou S, Schwartz DC, Freitag M, Ma LJ, Danchin EG, Henrissat B, Coutinho PM, Nelson DR, Straney D, Napoli CA, Barker BM, Gribskov M, Rep M, Kroken S, Molnar I, Rensing C, Kennell JC, Zamora J, Farman ML, Selker EU, Salamov A, Shapiro H, Pangilinan J, Lindquist E, Lamers C, Grigoriev IV, Geiser DM, Covert SF, Temporini E, Vanetten HD (2009)
The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion
PLoS Genet 5 :e1000618

Coleman JJ, Rounsley SD, Rodriguez-Carres M, Kuo A, Wasmann CC, Grimwood J, Schmutz J, Taga M, White GJ, Zhou S, Schwartz DC, Freitag M, Ma LJ, Danchin EG, Henrissat B, Coutinho PM, Nelson DR, Straney D, Napoli CA, Barker BM, Gribskov M, Rep M, Kroken S, Molnar I, Rensing C, Kennell JC, Zamora J, Farman ML, Selker EU, Salamov A, Shapiro H, Pangilinan J, Lindquist E, Lamers C, Grigoriev IV, Geiser DM, Covert SF, Temporini E, Vanetten HD (2009)
PLoS Genet 5 :e1000618