Name : Crystal Structure of Human Liver Carboxylesterase in complex with tacrine

Revelation date : 22-Apr-2003

Family : Carb_B_Chordata

Gene_locus : human-CES1

PDB file : ESTHER: header of PDB entry RCSB: Full entry


Ligand : Inhibitor Tacrine Ligand in structure: Ligplot

References (1)

Title : Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition - Bencharit_2003_Chem.Biol_10_341
Author(s) : Bencharit S , Morton CL , Hyatt JL , Kuhn P , Danks MK , Potter PM , Redinbo MR
Ref : Chemical Biology , 10 :341 , 2003
Abstract :
PubMedSearch : Bencharit_2003_Chem.Biol_10_341
PubMedID: 12725862
Gene_locus related to this paper: human-CES1

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 1MX1 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 1MX1 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 1MX1 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 1MX1 3D, interactive encyclopedia of proteins - PROTEOPEDIA server