1ODC

Name : Acetylcholinesterase complexed with N-4'-quinolyl-N'-9-(1,2,3,4-tetrahydroacridinyl)-1,8-diaminooctane at 2.2A resolution

Revelation date : 23-Mar-2005

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Wong, D.M., Greenblatt, H.M., Shaya, D., Carlier, P.R., Han, Y.F., Pang, Y.P., Silman, I., Sussman, J.L.

Ligand : Inhibitor Tacrine(8)-4-aminoquinoline Ligand in structure: Ligplot

References (1)

Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491
Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL
Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006
Abstract :
PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491
PubMedID: 16942022
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 1ODC Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 1ODC Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 1ODC Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 1ODC 3D, interactive encyclopedia of proteins - PROTEOPEDIA server