Full name : Wong Dawn M
First name : Dawn M
Mail : Virginia Tech\; Chemistry\; Department of Chemistry\; 3019 Hahn S.\; Virginia Tech\; Blacksburg\; 24061
Zip Code :
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Country : USA
Email : dawnwong@vt.edu
Phone : +15402314886
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Comment
| Title : Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates - Mutunga_2019_Int.J.Environ.Res.Public.Health_16_ |
| Author(s) : Mutunga JM , Ma M , Chen QH , Hartsel JA , Wong DM , Ding S , Totrov M , Carlier PR , Bloomquist JR |
| Ref : Int J Environ Research Public Health , 16 : , 2019 |
| Abstract : |
| PubMedSearch : Mutunga_2019_Int.J.Environ.Res.Public.Health_16_ |
| PubMedID: 31035318 |
| Title : Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae - Han_2018_Insect.Sci_25_721 |
| Author(s) : Han Q , Wong DM , Robinson H , Ding H , Lam PC , Totrov MM , Carlier PR , Li J |
| Ref : Insect Sci , 25 :721 , 2018 |
| Abstract : |
| PubMedSearch : Han_2018_Insect.Sci_25_721 |
| PubMedID: 28247978 |
| Gene_locus related to this paper: anoga-ACHE1 |
| Title : Select beta- and gamma-branched 1-alkylpyrazol-4-yl methylcarbamates exhibit high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase - Carlier_2018_Pestic.Biochem.Physiol_151_32 |
| Author(s) : Carlier PR , Chen QH , Verma A , Wong DM , Mutunga JM , Muller J , Islam R , Shimozono AM , Tong F , Li J , Totrov M , Bloomquist JR |
| Ref : Pestic Biochem Physiol , 151 :32 , 2018 |
| Abstract : |
| PubMedSearch : Carlier_2018_Pestic.Biochem.Physiol_151_32 |
| PubMedID: 30524149 |
| Title : Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis - Resnik-Docampo_2017_Nat.Cell.Biol_19_52 |
| Author(s) : Resnik-Docampo M , Koehler CL , Clark RI , Schinaman JM , Sauer V , Wong DM , Lewis S , D'Alterio C , Walker DW , Jones DL |
| Ref : Nat Cell Biol , 19 :52 , 2017 |
| Abstract : |
| PubMedSearch : Resnik-Docampo_2017_Nat.Cell.Biol_19_52 |
| PubMedID: 27992405 |
| Title : Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase - Camerino_2015_Bioorg.Med.Chem.Lett_25_4405 |
| Author(s) : Camerino E , Wong DM , Tong F , Korber F , Gross AD , Islam R , Viayna E , Mutunga JM , Li J , Totrov MM , Bloomquist JR , Carlier PR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :4405 , 2015 |
| Abstract : |
| PubMedSearch : Camerino_2015_Bioorg.Med.Chem.Lett_25_4405 |
| PubMedID: 26386602 |
| Title : Carbamate and pyrethroid resistance in the akron strain of Anopheles gambiae - Mutunga_2015_Pestic.Biochem.Physiol_121_116 |
| Author(s) : Mutunga JM , Anderson TD , Craft DT , Gross AD , Swale DR , Tong F , Wong DM , Carlier PR , Bloomquist JR |
| Ref : Pestic Biochem Physiol , 121 :116 , 2015 |
| Abstract : |
| PubMedSearch : Mutunga_2015_Pestic.Biochem.Physiol_121_116 |
| PubMedID: 26047119 |
| Title : 3-Oxoisoxazole-2(3H)-carboxamides and isoxazol-3-yl carbamates: Resistance-breaking acetylcholinesterase inhibitors targeting the malaria mosquito, Anopheles gambiae - Verma_2015_Bioorg.Med.Chem_23_1321 |
| Author(s) : Verma A , Wong DM , Islam R , Tong F , Ghavami M , Mutunga JM , Slebodnick C , Li J , Viayna E , Lam PC , Totrov MM , Bloomquist JR , Carlier PR |
| Ref : Bioorganic & Medicinal Chemistry , 23 :1321 , 2015 |
| Abstract : |
| PubMedSearch : Verma_2015_Bioorg.Med.Chem_23_1321 |
| PubMedID: 25684426 |
| Title : Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae - Wong_2013_Chem.Biol.Interact_203_314 |
| Author(s) : Wong DM , Li J , Lam PC , Hartsel JA , Mutunga JM , Totrov M , Bloomquist JR , Carlier PR |
| Ref : Chemico-Biological Interactions , 203 :314 , 2013 |
| Abstract : |
| PubMedSearch : Wong_2013_Chem.Biol.Interact_203_314 |
| PubMedID: 22989775 |
| Gene_locus related to this paper: anoga-ACHE1 |
| Title : Neurotoxicology of bis(n)-Tacrines on Blattella germanica and Drosophila melanogaster acetylcholinesterase - Mutunga_2013_Arch.Insect.Biochem.Physiol_83_180 |
| Author(s) : Mutunga JM , Boina DR , Anderson TD , Bloomquist JR , Carlier PR , Wong DM , Lam PC , Totrov MM |
| Ref : Archives of Insect Biochemistry & Physiology , 83 :180 , 2013 |
| Abstract : |
| PubMedSearch : Mutunga_2013_Arch.Insect.Biochem.Physiol_83_180 |
| PubMedID: 23740645 |
| Title : Re-engineering aryl methylcarbamates to confer high selectivity for inhibition of Anopheles gambiae versus human acetylcholinesterase - Hartsel_2012_Bioorg.Med.Chem.Lett_22_4593 |
| Author(s) : Hartsel JA , Wong DM , Mutunga JM , Ma M , Anderson TD , Wysinski A , Islam R , Wong EA , Paulson SL , Li J , Lam PC , Totrov MM , Bloomquist JR , Carlier PR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :4593 , 2012 |
| Abstract : |
| PubMedSearch : Hartsel_2012_Bioorg.Med.Chem.Lett_22_4593 |
| PubMedID: 22738634 |
| Gene_locus related to this paper: anoga-ACHE1 |
| Title : Select small core structure carbamates exhibit high contact toxicity to carbamate-resistant strain malaria mosquitoes, Anopheles gambiae (Akron) - Wong_2012_PLoS.One_7_e46712 |
| Author(s) : Wong DM , Li J , Chen QH , Han Q , Mutunga JM , Wysinski A , Anderson TD , Ding H , Carpenetti TL , Verma A , Islam R , Paulson SL , Lam PC , Totrov M , Bloomquist JR , Carlier PR |
| Ref : PLoS ONE , 7 :e46712 , 2012 |
| Abstract : |
| PubMedSearch : Wong_2012_PLoS.One_7_e46712 |
| PubMedID: 23049714 |
| Gene_locus related to this paper: anoga-ACHE1 |
| Title : Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae - Carlier_2008_Chem.Biol.Interact_175_368 |
| Author(s) : Carlier PR , Anderson TD , Wong DM , Hsu DC , Hartsel J , Ma M , Wong EA , Choudhury R , Lam PC , Totrov MM , Bloomquist JR |
| Ref : Chemico-Biological Interactions , 175 :368 , 2008 |
| Abstract : |
| PubMedSearch : Carlier_2008_Chem.Biol.Interact_175_368 |
| PubMedID: 18554580 |
| Gene_locus related to this paper: anoga-ACHE1 |
| Title : Bivalent ligands derived from Huperzine A as acetylcholinesterase inhibitors - Haviv_2007_Curr.Top.Med.Chem_7_375 |
| Author(s) : Haviv H , Wong DM , Silman I , Sussman JL |
| Ref : Curr Top Med Chem , 7 :375 , 2007 |
| Abstract : |
| PubMedSearch : Haviv_2007_Curr.Top.Med.Chem_7_375 |
| PubMedID: 17305579 |
| Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491 |
| Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006 |
| Abstract : |
| PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedID: 16942022 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase - Haviv_2005_J.Am.Chem.Soc_127_11029 |
| Author(s) : Haviv H , Wong DM , Greenblatt HM , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 127 :11029 , 2005 |
| Abstract : |
| PubMedSearch : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedID: 16076210 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Poster (79) X-ray structures of TcAChE complexed with (+)-huperzine a and (-)-huperzine b: structural evidence for an active-site rearrangement - |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :362 , 2004 |
| PubMedID: |
| Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363 |
| Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL |
| Ref : J Am Chem Soc , 125 :363 , 2003 |
| Abstract : |
| PubMedSearch : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedID: 12517147 |
| Gene_locus related to this paper: torca-ACHE |
| Title : 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates - Dvir_2002_Biochemistry_41_2970 |
| Author(s) : Dvir H , Wong DM , Harel M , Barril X , Orozco M , Luque FJ , Munoz-Torrero D , Camps P , Rosenberry TL , Silman I , Sussman JL |
| Ref : Biochemistry , 41 :2970 , 2002 |
| Abstract : |
| PubMedSearch : Dvir_2002_Biochemistry_41_2970 |
| PubMedID: 11863435 |
| Gene_locus related to this paper: torca-ACHE |
| Title : X-ray Structures of Torpedo californica Acetylcholinesterase Complexed with (+)-Huperzine A and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement - Dvir_2002_Biochemistry_41_10810 |
| Author(s) : Dvir H , Jiang H , Wong DM , Harel M , Chetrit M , He XC , Jin GY , Yu GL , Tang XC , Silman I , Bai DL , Sussman JL |
| Ref : Biochemistry , 41 :10810 , 2002 |
| Abstract : |
| PubMedSearch : Dvir_2002_Biochemistry_41_10810 |
| PubMedID: 12196020 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure of the human hepatic triglyceride lipase gene - Cai_1989_Biochemistry_28_8966 |
| Author(s) : Cai SJ , Wong DM , Chen SH , Chan L |
| Ref : Biochemistry , 28 :8966 , 1989 |
| Abstract : |
| PubMedSearch : Cai_1989_Biochemistry_28_8966 |
| PubMedID: 2605236 |
| Gene_locus related to this paper: human-LIPC |