Full name : Greenblatt Harry M
First name : Harry M
Mail : Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100
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Country : Israel
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| Title : Structure of Recombinant Human Carboxylesterase 1 Isolated from Whole Cabbage Looper Larvae - Greenblatt_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_F68_269 |
| Author(s) : Greenblatt HM , Otto TC , Kirkpatrick MG , Kovaleva E , Brown S , Buchman G , Cerasoli DM , Sussman JL |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , F68 :269 , 2012 |
| Abstract : |
| PubMedSearch : Greenblatt_2012_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_F68_269 |
| PubMedID: 22442219 |
| Gene_locus related to this paper: human-CES1 |
| Title : The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad - Paz_2009_J.Med.Chem_52_2543 |
| Author(s) : Paz A , Xie Q , Greenblatt HM , Fu W , Tang Y , Silman I , Qiu Z , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 52 :2543 , 2009 |
| Abstract : |
| PubMedSearch : Paz_2009_J.Med.Chem_52_2543 |
| PubMedID: 19326912 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime - Sanson_2009_J.Med.Chem_52_7593 |
| Author(s) : Sanson B , Nachon F , Colletier JP , Froment MT , Toker L , Greenblatt HM , Sussman JL , Ashani Y , Masson P , Silman I , Weik M |
| Ref : Journal of Medicinal Chemistry , 52 :7593 , 2009 |
| Abstract : |
| PubMedSearch : Sanson_2009_J.Med.Chem_52_7593 |
| PubMedID: 19642642 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge - Rydberg_2006_J.Med.Chem_49_5491 |
| Author(s) : Rydberg EH , Brumshtein B , Greenblatt HM , Wong DM , Shaya D , Williams LD , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of Medicinal Chemistry , 49 :5491 , 2006 |
| Abstract : |
| PubMedSearch : Rydberg_2006_J.Med.Chem_49_5491 |
| PubMedID: 16942022 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structural insights into substrate traffic and inhibition in acetylcholinesterase - Colletier_2006_EMBO.J_25_2746 |
| Author(s) : Colletier JP , Fournier D , Greenblatt HM , Stojan J , Sussman JL , Zaccai G , Silman I , Weik M |
| Ref : EMBO Journal , 25 :2746 , 2006 |
| Abstract : |
| PubMedSearch : Colletier_2006_EMBO.J_25_2746 |
| PubMedID: 16763558 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase - Haviv_2005_J.Am.Chem.Soc_127_11029 |
| Author(s) : Haviv H , Wong DM , Greenblatt HM , Carlier PR , Pang YP , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 127 :11029 , 2005 |
| Abstract : |
| PubMedSearch : Haviv_2005_J.Am.Chem.Soc_127_11029 |
| PubMedID: 16076210 |
| Gene_locus related to this paper: torca-ACHE |
| Title : The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design - Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| Author(s) : Greenblatt HM , Guillou C , Guenard D , Argaman A , Botti SA , Badet B , Thal C , Silman I , Sussman JL |
| Ref : Journal of the American Chemical Society , 126 :15405 , 2004 |
| Abstract : |
| PubMedSearch : Greenblatt_2004_J.Am.Chem.Soc_126_15405 |
| PubMedID: 15563167 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Poster (47) Conformational plasticity of acetylcholinesterase - |
| Author(s) : Silman I , Greenblatt HM , Zeev-Ben-Mordehai T , Sussman JL |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :346 , 2004 |
| PubMedID: |
| Title : Poster (74) Structural studies on torpedo californica acetylcholinesterase in complex with a substrate analogue - |
| Author(s) : Colletier JP , Fournier D , Greenblatt HM , Sussman JL , Zaccai G , Silman I , Weik M |
| Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :359 , 2004 |
| PubMedID: |
| Title : Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease - Greenblatt_2003_J.Mol.Neurosci_20_369 |
| Author(s) : Greenblatt HM , Dvir H , Silman I , Sussman JL |
| Ref : Journal of Molecular Neuroscience , 20 :369 , 2003 |
| Abstract : |
| PubMedSearch : Greenblatt_2003_J.Mol.Neurosci_20_369 |
| PubMedID: 14501022 |
| Title : Acetylcholinesterase Complexed with Bivalent Ligands Related to Huperzine A: Experimental Evidence for Species-Dependent Protein-Ligand Complementarity - Wong_2003_J.Am.Chem.Soc_125_363 |
| Author(s) : Wong DM , Greenblatt HM , Dvir H , Carlier PR , Han YF , Pang YP , Silman I , Sussman JL |
| Ref : J Am Chem Soc , 125 :363 , 2003 |
| Abstract : |
| PubMedSearch : Wong_2003_J.Am.Chem.Soc_125_363 |
| PubMedID: 12517147 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A structure-based design approach to the development of novel, reversible AChE inhibitors - Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| Author(s) : Doucet-Personeni C , Bentley PD , Fletcher RJ , Kinkaid A , Kryger G , Pirard B , Taylor A , Taylor R , Taylor J , Viner R , Silman I , Sussman JL , Greenblatt HM , Lewis T |
| Ref : Journal of Medicinal Chemistry , 44 :3203 , 2001 |
| Abstract : |
| PubMedSearch : Doucet-Personeni_2001_J.Med.Chem_44_3203 |
| PubMedID: 11563919 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 A resolution - Greenblatt_1999_FEBS.Lett_463_321 |
| Author(s) : Greenblatt HM , Kryger G , Lewis T , Silman I , Sussman JL |
| Ref : FEBS Letters , 463 :321 , 1999 |
| Abstract : |
| PubMedSearch : Greenblatt_1999_FEBS.Lett_463_321 |
| PubMedID: 10606746 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level - Millard_1999_Biochemistry_38_7032 |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Greenblatt HM , Harel M , Raves ML , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : Biochemistry , 38 :7032 , 1999 |
| Abstract : |
| PubMedSearch : Millard_1999_Biochemistry_38_7032 |
| PubMedID: 10353814 |
| Gene_locus related to this paper: torca-ACHE |
| Title : A preliminary comparison of structural models for catalytic intermediates of acetylcholinesterase - Silman_1999_Chem.Biol.Interact_119-120_43 |
| Author(s) : Silman I , Millard CB , Ordentlich A , Greenblatt HM , Harel M , Barak D , Shafferman A , Sussman JL |
| Ref : Chemico-Biological Interactions , 119-120 :43 , 1999 |
| Abstract : |
| PubMedSearch : Silman_1999_Chem.Biol.Interact_119-120_43 |
| PubMedID: 10421437 |
| Gene_locus related to this paper: torca-ACHE |
| Title : Effect of mutations within the peripheral anionic site on the stability of acetylcholinesterase - Morel_1999_Mol.Pharmacol_55_982 |
| Author(s) : Morel N , Bon S , Greenblatt HM , Van Belle D , Wodak SJ , Sussman JL , Massoulie J , Silman I |
| Ref : Molecular Pharmacology , 55 :982 , 1999 |
| Abstract : |
| PubMedSearch : Morel_1999_Mol.Pharmacol_55_982 |
| PubMedID: 10347238 |
| Title : Crystal structure of Aged phosphorylated and phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Gene_locus related to this paper: torca-ACHE |
| Title : Crystal Structures of Complexes of E2020-Related Compounds with Torpedo Californica Acetylcholinesterase - |
| Author(s) : Greenblatt HM , Kryger G , Harel M , Lewis T , Taylor J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :371-371 , 1998 |
| PubMedID: |
| Title : Alternative Crystal Forms of Torpedo Californica Acetylcholinesterase - |
| Author(s) : Raves ML , Greenblatt HM , Kryger G , Nicolas A , Ravelli RB , Harel M , Kroon J , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :372 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :425 , 1998 |
| PubMedID: |
| Title : Crystal Structures of Aged Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase - |
| Author(s) : Millard CB , Kryger G , Ordentlich A , Harel M , Raves ML , Greenblatt HM , Segall Y , Barak D , Shafferman A , Silman I , Sussman JL |
| Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :454 , 1998 |
| PubMedID: |
| Title : Carboxypeptidase A: native, zinc-removed and mercury-replaced forms - Greenblatt_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_289 |
| Author(s) : Greenblatt HM , Feinberg H , Tucker PA , Shoham G |
| Ref : Acta Crystallographica D Biol Crystallogr , 54 :289 , 1998 |
| Abstract : |
| PubMedSearch : Greenblatt_1998_Acta.Crystallogr.D.Biol.Crystallogr_54_289 |
| PubMedID: 9867434 |
| Title : Streptomyces griseus aminopeptidase: X-ray crystallographic structure at 1.75 A resolution - Greenblatt_1997_J.Mol.Biol_265_620 |
| Author(s) : Greenblatt HM , Almog O , Maras B , Spungin-Bialik A , Barra D , Blumberg S , Shoham G |
| Ref : Journal of Molecular Biology , 265 :620 , 1997 |
| Abstract : |
| PubMedSearch : Greenblatt_1997_J.Mol.Biol_265_620 |
| PubMedID: 9048953 |
| Title : Aminopeptidase from Streptomyces griseus: primary structure and comparison with other zinc-containing aminopeptidases - Maras_1996_Eur.J.Biochem_236_843 |
| Author(s) : Maras B , Greenblatt HM , Shoham G , Spungin-Bialik A , Blumberg S , Barra D |
| Ref : European Journal of Biochemistry , 236 :843 , 1996 |
| Abstract : |
| PubMedSearch : Maras_1996_Eur.J.Biochem_236_843 |
| PubMedID: 8665903 |