4TVK

Name : Torpedo californica Acetylcholinesterase in complex with a chlorotacrine-juglone hybrid inhibitor

Revelation date : 08-Oct-2014

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Pesaresi, A., Samez, S., Lamba, D.

Ligand :

References (1)

Title : Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects - Nepovimova_2014_J.Med.Chem_57_8576
Author(s) : Nepovimova E , Uliassi E , Korabecny J , Pena-Altamira LE , Samez S , Pesaresi A , Garcia GE , Bartolini M , Andrisano V , Bergamini C , Fato R , Lamba D , Roberti M , Kuca K , Monti B , Bolognesi ML
Ref : Journal of Medicinal Chemistry , 57 :8576 , 2014
PubMedID: 25259726
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 4TVK Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4TVK Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4TVK Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4TVK 3D, interactive encyclopedia of proteins - PROTEOPEDIA server