Lamba D

General

Full name : Lamba Doriano

First name : Doriano

Mail : Istituto di Cristallografia -C.N.R.\; Unita Operativa di Trieste\; Area Science Park -Basovizza Strada Statale 14 -Km. 163.5\; I-34149 Trieste

Zip Code :

City :

Country : Italy

Email : doriano.lamba@elettra.eu

Phone : +39 040 375 7527

Fax :

Website : \/\/www.ic.cnr.it\/icnew\/site\/index.php?option=com_content&view=article&id=73&Itemid=73

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References (20)

Title : Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles - Stojan_2024_Protein.Sci_33_e4977
Author(s) : Stojan J , Pesaresi A , Meden A , Lamba D
Ref : Protein Science , 33 :e4977 , 2024
PubMedID: 38591646

Title : Kinetic and structural studies on the inhibition of acetylcholinesterase and butyrylcholinesterase by a series of multitarget-directed galantamine-peptide derivatives - Pesaresi_2022_Chem.Biol.Interact__110092
Author(s) : Pesaresi A , Lamba D , Vezenkov L , Tsekova D , Lozanov V
Ref : Chemico-Biological Interactions , :110092 , 2022
PubMedID: 35987277

Title : Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine - Lamba_2022_Int.J.Mol.Sci_23_
Author(s) : Lamba D , Pesaresi A
Ref : Int J Mol Sci , 23 : , 2022
PubMedID: 35563466

Title : Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease - Chalupova_2019_Eur.J.Med.Chem_168_491
Author(s) : Chalupova K , Korabecny J , Bartolini M , Monti B , Lamba D , Caliandro R , Pesaresi A , Brazzolotto X , Gastellier AJ , Nachon F , Pejchal J , Jarosova M , Hepnarova V , Jun D , Hrabinova M , Dolezal R , Karasova JZ , Mzik M , Kristofikova Z , Misik J , Muckova L , Jost P , Soukup O , Benkova M , Setnicka V , Habartova L , Chvojkova M , Kleteckova L , Vales K , Mezeiova E , Uliassi E , Valis M , Nepovimova E , Bolognesi ML , Kuca K
Ref : Eur Journal of Medicinal Chemistry , 168 :491 , 2019
PubMedID: 30851693
Gene_locus related to this paper: torca-ACHE

Title : Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues - Caliandro_2018_J.Enzyme.Inhib.Med.Chem_33_794
Author(s) : Caliandro R , Pesaresi A , Cariati L , Procopio A , Oliverio M , Lamba D
Ref : J Enzyme Inhib Med Chem , 33 :794 , 2018
PubMedID: 29651884
Gene_locus related to this paper: torca-ACHE

Title : Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography - Zha_2016_J.Med.Chem_59_114
Author(s) : Zha X , Lamba D , Zhang L , Lou Y , Xu C , Kang D , Chen L , Xu Y , De Simone A , Samez S , Pesaresi A , Stojan J , Lopez MG , Egea J , Andrisano V , Bartolini M
Ref : Journal of Medicinal Chemistry , 59 :114 , 2016
PubMedID: 26632651
Gene_locus related to this paper: torca-ACHE

Title : Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects - Nepovimova_2014_J.Med.Chem_57_8576
Author(s) : Nepovimova E , Uliassi E , Korabecny J , Pena-Altamira LE , Samez S , Pesaresi A , Garcia GE , Bartolini M , Andrisano V , Bergamini C , Fato R , Lamba D , Roberti M , Kuca K , Monti B , Bolognesi ML
Ref : Journal of Medicinal Chemistry , 57 :8576 , 2014
PubMedID: 25259726
Gene_locus related to this paper: torca-ACHE

Title : Evaluation and computational characterization of the facilitated transport of Glc carbon C-1 oxime reactivators across a blood brain barrier model - Bhonsle_2013_Chem.Biol.Interact_203_129
Author(s) : Bhonsle JB , Causey R , Oyler BL , Bartolucci C , Lamba D , Pesaresi A , Bhamare NK , Soojhawon I , Garcia GE
Ref : Chemico-Biological Interactions , 203 :129 , 2013
PubMedID: 23073172

Title : Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group - Bartolucci_2012_Biochem.J_444_269
Author(s) : Bartolucci C , Stojan J , Yu QS , Greig NH , Lamba D
Ref : Biochemical Journal , 444 :269 , 2012
PubMedID: 22390827
Gene_locus related to this paper: torma-ACHE

Title : Insights into the fatty acid chain length specificity of the carboxylesterase PA3859 from Pseudomonas aeruginosa: A combined structural, biochemical and computational study - Pesaresi_2010_Biochimie_92_1787
Author(s) : Pesaresi A , Lamba D
Ref : Biochimie , 92 :1787 , 2010
PubMedID: 20850500
Gene_locus related to this paper: pseae-PA3859

Title : Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives - Bartolucci_2010_J.Med.Chem_53_745
Author(s) : Bartolucci C , Haller LA , Jordis U , Fels G , Lamba D
Ref : Journal of Medicinal Chemistry , 53 :745 , 2010
PubMedID: 20025280
Gene_locus related to this paper: torca-ACHE

Title : Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819) - Bartolucci_2006_J.Med.Chem_49_5051
Author(s) : Bartolucci C , Siotto M , Ghidini E , Amari G , Bolzoni PT , Racchi M , Villetti G , Delcanale M , Lamba D
Ref : Journal of Medicinal Chemistry , 49 :5051 , 2006
PubMedID: 16913695
Gene_locus related to this paper: torca-ACHE

Title : Heterologous expression, purification, crystallization, X-ray analysis and phasing of the acetyl xylan esterase from Bacillus pumilus - Krastanova_2005_Biochim.Biophys.Acta_1748_222
Author(s) : Krastanova I , Guarnaccia C , Zahariev S , Degrassi G , Lamba D
Ref : Biochimica & Biophysica Acta , 1748 :222 , 2005
PubMedID: 15769599
Gene_locus related to this paper: bacpu-AXE

Title : Isolation, characterization, and heterologous expression of a carboxylesterase of Pseudomonas aeruginosa PAO1 - Pesaresi_2005_Curr.Microbiol_50_102
Author(s) : Pesaresi A , Devescovi G , Lamba D , Venturi V , Degrassi G
Ref : Curr Microbiol , 50 :102 , 2005
PubMedID: 15717224
Gene_locus related to this paper: pseae-PA3859

Title : Crystallization, X-ray diffraction analysis and phasing of carboxylesterase PA3859 from Pseudomonas aeruginosa - Pesaresi_2005_Biochim.Biophys.Acta_1752_197
Author(s) : Pesaresi A , Lamba D
Ref : Biochimica & Biophysica Acta , 1752 :197 , 2005
PubMedID: 16120484
Gene_locus related to this paper: pseae-PA3859

Title : Purification, crystallization and preliminary X-ray analysis of an acetylxylan esterase from Bacillus pumilus. Erratum - Benini_2004_Acta.Crystallogr.D.Biol.Crystallogr_60_1346
Author(s) : Benini S , Degrassi G , Krastanova I , Lamba D , Venturi V
Ref : Acta Crystallographica D Biol Crystallogr , 60 :1346 , 2004
PubMedID: 11717513

Title : Accurate prediction of the bound conformation of galanthamine in the active site of Torpedo californica acetylcholinesterase using molecular docking - Pilger_2001_J.Mol.Graph.Model_19_288
Author(s) : Pilger C , Bartolucci C , Lamba D , Tropsha A , Fels G
Ref : J Mol Graph Model , 19 :288 , 2001
PubMedID: 11449566

Title : Three-dimensional structure of a complex of galanthamine (Nivalin) with acetylcholinesterase from Torpedo californica: implications for the design of new anti-Alzheimer drugs - Bartolucci_2001_Proteins_42_182
Author(s) : Bartolucci C , Perola E , Pilger C , Fels G , Lamba D
Ref : Proteins , 42 :182 , 2001
PubMedID: 11119642
Gene_locus related to this paper: torca-ACHE

Title : Back Door Opening Implied by the Crystal Structure of a Carbamoylated Acetylcholinesterase - Bartolucci_1999_Biochemistry_38_5714
Author(s) : Bartolucci C , Perola E , Cellai L , Brufani M , Lamba D
Ref : Biochemistry , 38 :5714 , 1999
PubMedID: 10231521
Gene_locus related to this paper: torca-ACHE

Title : Long chain analogs of physostigmine as potential drugs for Alzheimer's disease: new insights into the mechanism of action in the inhibition of acetylcholinesterase. - Perola_1997_Biochim.Biophys.Acta_1343_41
Author(s) : Perola E , Cellai L , Lamba D , Filocamo L , Brufani M
Ref : Biochimica & Biophysica Acta , 1343 :41 , 1997
PubMedID: 9428657