7L50
Name : Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL19421119
Revelation date : 11-Aug-2021
Family : Monoglyceridelipase_lysophospholip
Gene_locus : human-MGLL
PDB file : ESTHER: header of PDB entry RCSB: Full entry
Comment
Qin, L.,Lane, W.,Skene, R.J.
Ligand : Inhibitor SCHEMBL19421119 Ligand in structure: Ligplot
References (1)
| Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
| Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Ikeda_2021_J.Med.Chem__ |
| PubMedID: 34328319 |
| Gene_locus related to this paper: human-MGLL |
Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server
Databases
PDB-Sum : 7L50 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP : 7L50 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP : 7L50 Structural Classification Of Protein - SCOP server
PROTEOPEDIA : 7L50 3D, interactive encyclopedia of proteins - PROTEOPEDIA server