8AI7

Name : Human butyrylcholinesterase in complex with Cpd-6-8AI7

Revelation date : 01-Feb-2023

Family : BCHE

Gene_locus : human-BCHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Anze Meden, Damijan Knez, Xavier Brazzolotto, Fabrice Modeste, Andrej Perdih, Anja Pislar, Masa Zorman, Milica Denic, Stane Pajk, Florian Nachon, Stanislav Gobec

Ligand :

References (2)

Title : Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Eur.J.Med.Chem_247_115048
Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Zorovic M , Denic M , Pajk S , Zivin M , Nachon F , Gobec S
Ref : Eur Journal of Medicinal Chemistry , 247 :115048 , 2022
PubMedID: 36586299
Gene_locus related to this paper: human-BCHE

Title : Pseudo-irreversible butyrylcholinesterase inhibitors: SAR, kinetic, computational, and crystallographic study of the N-dialkyl O-arylcarbamate warhead - Meden_2022_Chemrxiv__
Author(s) : Meden A , Knez D , Brazzolotto X , Modeste F , Perdih A , Pislar A , Zorman M , Denic M , Pajk S , Nachon F , Gobec S
Ref : Chemrxiv , : , 2022
PubMedID:
Gene_locus related to this paper: human-BCHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 8AI7 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 8AI7 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 8AI7 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 8AI7 3D, interactive encyclopedia of proteins - PROTEOPEDIA server