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Structure Report for: 4A16

Name|Structure of mouse Acetylcholinesterase complex with Huprine derivative
Revelation date|28-Mar-2012
Family|ACHE: there are 538 genes in this family, 315 structure(s)
Gene_locus|mouse-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Carletti, E., Colletier, J.P., Nachon, F., Weik, M., Ronco, C., Jean, L., Renard, P.Y.
Ligand|Inhibitor: H34 Ligand in structure: Ligplot


Reference

    Title: Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography
    Ronco C, Carletti E, Colletier JP, Weik M, Nachon F, Jean L, Renard PY
    Ref: ChemMedChem, 7:400, 2012 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum4A16 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4A16 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4A16 Structural Classification Of Protein - SCOP server
PROTEOPEDIA4a16 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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