Tree Display

AceDB Schema

XML Display


Structure Report for: 4OD0

Name|Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea 2
Revelation date|24-Sep-2014
Family|Epoxide_hydrolase: there are 1154 genes in this family, 155 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Lee, K.S.S., Liu, J., Wagner, K.M., Pakhomova, S., Dong, H., Morriseau, C., Fu, S.H., Yang, J., Wang, P., Ulu, A., Mate, C., Nguyen, L., Wullf, H., Eldin, M.L., Mara, A.A., Newcomer, M.E., Zeldin, D.C., Hammock, B.D.
Ligand|Inhibitor: TPPU Ligand in structure: Ligplot


    Title: Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy
    Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P and Hammock BD <9 more author(s)>
    Ref: Journal of Medicinal Chemistry, 57:7016, 2014 : PubMed


Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

no Image


PDB-Sum4OD0 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP4OD0 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP4OD0 Structural Classification Of Protein - SCOP server
PROTEOPEDIA4od0 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

Acknowledgements and disclaimer