4-methylumbelliferyl-heptanoate

General

Type : Coumarin || Chromen

Chemical_Nomenclature : (4-methyl-2-oxochromen-7-yl) heptanoate

Canonical SMILES : CCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C

InChI : InChI=1S\/C17H20O4\/c1-3-4-5-6-7-16(18)20-13-8-9-14-12(2)10-17(19)21-15(14)11-13\/h8-11H,3-7H2,1-2H3

InChIKey : FFNBFZWIBOIPIV-UHFFFAOYSA-N

Other name(s) : 4-Methylumbelliferyl heptanoate, 4-MU-Heptanoate, 4MU-Heptanoate, 4MU-C7, 4-MUH, 4-methyl-2-oxo-2h-chromen-7-yl heptanoate, 4-Methylumbelliferyl enanthate, 4-methyl-2-oxochromen-7-yl heptanoate, Heptanoic acid 4-methylumbelliferyl ester, 4-Methylumbelliferone heptanoate, 4-Methylumbelliferone-heptanoate


MW : 288.33

Formula : C17H20O4

CAS_number : 18319-92-1

PubChem :

UniChem :

Iuphar :

References (5)

Title : Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus - Fellner_2020_ACS.Infect.Dis_6_2771
Author(s) : Fellner M , Lentz CS , Jamieson SA , Brewster JL , Chen L , Bogyo M , Mace PD
Ref : ACS Infect Dis , 6 :2771 , 2020
PubMedID: 32865965
Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188

Title : Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase - Fako_2015_J.Med.Chem_58_778
Author(s) : Fako VE , Wu X , Pflug B , Liu JY , Zhang JT
Ref : Journal of Medicinal Chemistry , 58 :778 , 2015
PubMedID: 25513712

Title : Novel antagonists of the thioesterase domain of human fatty acid synthase - Richardson_2007_Mol.Cancer.Ther_6_2120
Author(s) : Richardson RD , Smith JW
Ref : Mol Cancer Ther , 6 :2120 , 2007
PubMedID: 17620441
Gene_locus related to this paper: human-FASN

Title : High-resolution crystal structure of plant carboxylesterase AeCXE1, from Actinidia eriantha, and its complex with a high-affinity inhibitor paraoxon - Ileperuma_2007_Biochemistry_46_1851
Author(s) : Ileperuma NR , Marshall SD , Squire CJ , Baker HM , Oakeshott JG , Russell RJ , Plummer KM , Newcomb RD , Baker EN
Ref : Biochemistry , 46 :1851 , 2007
PubMedID: 17256879
Gene_locus related to this paper: actde-CXE1

Title : Fluorometric assay for the hydrolytic activity of lipase using fatty acyl esters of 4-methylumbelliferone -
Author(s) : Jacks TJ , Kircher HW
Ref : Analytical Biochemistry , 21 :279 , 1967
PubMedID: 5582971