HODA-6-phenyl

General

Type : Meta-Cleavage-Product

Chemical_Nomenclature : (4Z)-2-Hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid

Canonical SMILES : C1=CC=C(C=C1)C(=CC=CC(=O)C(=O)O)O

InChI : InChI=1S\/C12H10O4\/c13-10(9-5-2-1-3-6-9)7-4-8-11(14)12(15)16\/h1-8,14H,(H,15,16)

InChIKey : YOVXRIACERVBAG-LJBIEAABSA-N

Other name(s) : 6-Hydroxy-2-oxo-6-phenylhexa-3,5-dienoic acid  ||  2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate  ||  2,6-Dioxo-6-phenylhexa-3-enoate  ||  6-phenyl-HODA  ||  C01273


MW : 218.20

Formula : C12H10O4

CAS_number :

PubChem : 5280419

UniChem : YOVXRIACERVBAG-LJBIEAABSA-N

Target

Structures : No structure

Families : Carbon-carbon_bond_hydrolase

References (8)

Title : The Lid Domain of the MCP Hydrolase DxnB2 Contributes to the Reactivity toward Recalcitrant PCB Metabolites - Ruzzini_2013_Biochemistry_52_5685
Author(s) : Ruzzini AC , Bhowmik S , Yam KC , Ghosh S , Bolin JT , Eltis LD
Ref : Biochemistry , 52 :5685 , 2013
Abstract :
PubMedSearch : Ruzzini_2013_Biochemistry_52_5685
PubMedID: 23879719
Gene_locus related to this paper: sphww-a5j2a5

Title : A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase - Ruzzini_2013_Biochemistry_52_7428
Author(s) : Ruzzini AC , Bhowmik S , Ghosh S , Yam KC , Bolin JT , Eltis LD
Ref : Biochemistry , 52 :7428 , 2013
Abstract :
PubMedSearch : Ruzzini_2013_Biochemistry_52_7428
PubMedID: 24067021
Gene_locus related to this paper: sphww-a5j2a5

Title : Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad - Ruzzini_2012_J.Am.Chem.Soc_134_4615
Author(s) : Ruzzini AC , Ghosh S , Horsman GP , Foster LJ , Bolin JT , Eltis LD
Ref : J Am Chem Soc , 134 :4615 , 2012
Abstract :
PubMedSearch : Ruzzini_2012_J.Am.Chem.Soc_134_4615
PubMedID: 22339283
Gene_locus related to this paper: burxl-bphD

Title : The molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerization - Bhowmik_2007_J.Biol.Chem_282_36377
Author(s) : Bhowmik S , Horsman GP , Bolin JT , Eltis LD
Ref : Journal of Biological Chemistry , 282 :36377 , 2007
Abstract :
PubMedSearch : Bhowmik_2007_J.Biol.Chem_282_36377
PubMedID: 17932031
Gene_locus related to this paper: burxl-bphD

Title : The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad - Horsman_2007_J.Biol.Chem_282_19894
Author(s) : Horsman GP , Bhowmik S , Seah SY , Kumar P , Bolin JT , Eltis LD
Ref : Journal of Biological Chemistry , 282 :19894 , 2007
Abstract :
PubMedSearch : Horsman_2007_J.Biol.Chem_282_19894
PubMedID: 17442675
Gene_locus related to this paper: burxl-bphD

Title : Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway - Horsman_2006_Biochemistry_45_11071
Author(s) : Horsman GP , Ke J , Dai S , Seah SY , Bolin JT , Eltis LD
Ref : Biochemistry , 45 :11071 , 2006
Abstract :
PubMedSearch : Horsman_2006_Biochemistry_45_11071
PubMedID: 16964968
Gene_locus related to this paper: burxl-bphD

Title : A series of crystal structures of a meta-cleavage product hydrolase from Pseudomonas fluorescens IP01 (CumD) complexed with various cleavage products - Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491
Author(s) : Fushinobu S , Jun SY , Hidaka M , Nojiri H , Yamane H , Shoun H , Omori T , Wakagi T
Ref : Biosci Biotechnol Biochem , 69 :491 , 2005
Abstract :
PubMedSearch : Fushinobu_2005_Biosci.Biotechnol.Biochem_69_491
PubMedID: 15784976
Gene_locus related to this paper: psefl-cumD

Title : Purification and preliminary characterization of a serine hydrolase involved in the microbial degradation of polychlorinated biphenyls - Seah_1998_J.Biol.Chem_273_22943
Author(s) : Seah SY , Terracina G , Bolin JT , Riebel P , Snieckus V , Eltis LD
Ref : Journal of Biological Chemistry , 273 :22943 , 1998
Abstract :
PubMedSearch : Seah_1998_J.Biol.Chem_273_22943
PubMedID: 9722515
Gene_locus related to this paper: burxl-bphD