Substrate

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Substrate Report for: 15-Hete-G

prostaglandin E2 -glycerol [PGE2 -G]) and the 15-lipoxygenase (15-hydroxy-eicosatetraenoyl-glycerol [15-HETE-G]) are the metabolites of 2-AG derived respectively from cyclooxygenase-2 and 15-lipoxygenase activities


General
Type Acyl-Glycerol, Cannabinoid-Receptor-ligand, Natural
Chemical_Nomenclature 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoate
Canonical SMILES CCCCCC(C=CC=CCC=CCC=CCCCC(=O)OC(CO)CO)O
InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(26)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-22(19-24)20-25/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-/m0/s1
InChIKey FCHYNXGUKIEWGL-BPVVGZHASA-N
Other name(s) 15-HETE-G ; 2-(15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycerol ; 15S-HETE-G ; LMGL01010030 ; 15-hydroxy-eicosatetraenoyl-glycerol
________________________________________________________________________________________________
MW|394.5
Formula|C23H38O5
CAS_number|
PubChem|10200684
UniChem|FCHYNXGUKIEWGL-BPVVGZHASA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: 15-Hete-G
    Title: Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways
    Turcotte C, Dumais E, Archambault AS, Martin C, Blanchet MR, Bissonnette E, Boulet LP, Laviolette M, Di Marzo V, Flamand N
    Ref: J Leukoc Biol, 106:1337, 2019 : PubMed