Interpro : IPR003140 Phospholipase\/carboxylesterase\/thioesterase PLP_Cesterase PLipase\/COase\/thioEstase
PIRSF : PIRSF016033 esterase
Pdoc : No Pdoc
Pfam : PF02230 Abhydrolase_2
Prints : No Print
EC Number : 3.1.1.5
Title : Thioesterase enzyme families: Functions, structures, and mechanisms - Caswell_2021_Protein.Sci__ |
Author(s) : Caswell BT , de Carvalho CC , Nguyen H , Roy M , Nguyen T , Cantu DC |
Ref : Protein Science , : , 2021 |
Abstract : Caswell_2021_Protein.Sci__ |
ESTHER : Caswell_2021_Protein.Sci__ |
PubMedSearch : Caswell_2021_Protein.Sci__ |
PubMedID: 34921469 |
Title : Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling - Wepy_2019_J.Lipid.Res_60_360 |
Author(s) : Wepy JA , Galligan JJ , Kingsley PJ , Xu S , Goodman MC , Tallman KA , Rouzer CA , Marnett LJ |
Ref : J Lipid Res , 60 :360 , 2019 |
Abstract : Wepy_2019_J.Lipid.Res_60_360 |
ESTHER : Wepy_2019_J.Lipid.Res_60_360 |
PubMedSearch : Wepy_2019_J.Lipid.Res_60_360 |
PubMedID: 30482805 |
Gene_locus related to this paper: human-LYPLA2 |
Title : Protein depalmitoylases - Won_2018_Crit.Rev.Biochem.Mol.Biol_53_83 |
Author(s) : Won SJ , Cheung See Kit M , Martin BR |
Ref : Crit Rev Biochem Mol Biol , 53 :83 , 2018 |
Abstract : Won_2018_Crit.Rev.Biochem.Mol.Biol_53_83 |
ESTHER : Won_2018_Crit.Rev.Biochem.Mol.Biol_53_83 |
PubMedSearch : Won_2018_Crit.Rev.Biochem.Mol.Biol_53_83 |
PubMedID: 29239216 |
Title : A hydrophobic anchor mechanism defines a deacetylase family that suppresses host response against YopJ effectors - Burger_2017_Nat.Commun_8_2201 |
Author(s) : Burger M , Willige BC , Chory J |
Ref : Nat Commun , 8 :2201 , 2017 |
Abstract : Burger_2017_Nat.Commun_8_2201 |
ESTHER : Burger_2017_Nat.Commun_8_2201 |
PubMedSearch : Burger_2017_Nat.Commun_8_2201 |
PubMedID: 29259199 |
Gene_locus related to this paper: maize-b6t1C9 , arath-SOBR1 , arath-SOBRL , arath-AT5G20060 |
Title : Molecular Mechanism for Isoform-Selective Inhibition of Acyl Protein Thioesterases 1 and 2 (APT1 and APT2) - Won_2016_ACS.Chem.Biol_11_3374 |
Author(s) : Won SJ , Davda D , Labby KJ , Hwang SY , Pricer R , Majmudar JD , Armacost KA , Rodriguez LA , Rodriguez CL , Chong FS , Torossian KA , Palakurthi J , Hur ES , Meagher JL , Brooks CL, 3rd , Stuckey JA , Martin BR |
Ref : ACS Chemical Biology , 11 :3374 , 2016 |
Abstract : Won_2016_ACS.Chem.Biol_11_3374 |
ESTHER : Won_2016_ACS.Chem.Biol_11_3374 |
PubMedSearch : Won_2016_ACS.Chem.Biol_11_3374 |
PubMedID: 27748579 |
Gene_locus related to this paper: human-LYPLA2 |
Title : Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution - Ma_2013_Appl.Microbiol.Biotechnol_97_4897 |
Author(s) : Ma J , Wu L , Guo F , Gu J , Tang X , Jiang L , Liu J , Zhou J , Yu H |
Ref : Applied Microbiology & Biotechnology , 97 :4897 , 2013 |
Abstract : Ma_2013_Appl.Microbiol.Biotechnol_97_4897 |
ESTHER : Ma_2013_Appl.Microbiol.Biotechnol_97_4897 |
PubMedSearch : Ma_2013_Appl.Microbiol.Biotechnol_97_4897 |
PubMedID: 22987200 |
Gene_locus related to this paper: rhos4-q3j2v1 |
Title : Large-scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis - Filippova_2013_J.Biol.Chem_288_10522 |
Author(s) : Filippova EV , Weston LA , Kuhn ML , Geissler B , Gehring AM , Armoush N , Adkins CT , Minasov G , Dubrovska I , Shuvalova L , Winsor JR , Lavis LD , Satchell KJ , Becker DP , Anderson WF , Johnson RJ |
Ref : Journal of Biological Chemistry , 288 :10522 , 2013 |
Abstract : Filippova_2013_J.Biol.Chem_288_10522 |
ESTHER : Filippova_2013_J.Biol.Chem_288_10522 |
PubMedSearch : Filippova_2013_J.Biol.Chem_288_10522 |
PubMedID: 23430251 |
Gene_locus related to this paper: fratt-q5ni32 |
Title : Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases - Burger_2012_J.Lipid.Res_53_43 |
Author(s) : Burger M , Zimmermann TJ , Kondoh Y , Stege P , Watanabe N , Osada H , Waldmann H , Vetter IR |
Ref : J Lipid Res , 53 :43 , 2012 |
Abstract : Burger_2012_J.Lipid.Res_53_43 |
ESTHER : Burger_2012_J.Lipid.Res_53_43 |
PubMedSearch : Burger_2012_J.Lipid.Res_53_43 |
PubMedID: 22052940 |
Gene_locus related to this paper: human-LYPLAL1 |
Title : Regulation and structure of YahD, a copper-inducible alpha\/beta serine hydrolase of Lactococcus lactis IL1403 - Martinez_2011_FEMS.Microbiol.Lett_314_57 |
Author(s) : Martinez J , Mancini S , Tauberger E , Weise C , Saenger W , Solioz M |
Ref : FEMS Microbiology Letters , 314 :57 , 2011 |
Abstract : Martinez_2011_FEMS.Microbiol.Lett_314_57 |
ESTHER : Martinez_2011_FEMS.Microbiol.Lett_314_57 |
PubMedSearch : Martinez_2011_FEMS.Microbiol.Lett_314_57 |
PubMedID: 21059179 |
Gene_locus related to this paper: lacla-YAHD |
Title : ThYme: a database for thioester-active enzymes - Cantu_2011_Nucleic.Acids.Res_39_D342 |
Author(s) : Cantu DC , Chen Y , Lemons ML , Reilly PJ |
Ref : Nucleic Acids Research , 39 :D342 , 2011 |
Abstract : Cantu_2011_Nucleic.Acids.Res_39_D342 |
ESTHER : Cantu_2011_Nucleic.Acids.Res_39_D342 |
PubMedSearch : Cantu_2011_Nucleic.Acids.Res_39_D342 |
PubMedID: 21045059 |
Title : Thioesterases: a new perspective based on their primary and tertiary structures. - Cantu_2010_Protein.Sci_19_1281 |
Author(s) : Cantu DC , Chen Y , Reilly PJ |
Ref : Protein Science , 19 :1281 , 2010 |
Abstract : Cantu_2010_Protein.Sci_19_1281 |
ESTHER : Cantu_2010_Protein.Sci_19_1281 |
PubMedSearch : Cantu_2010_Protein.Sci_19_1281 |
PubMedID: 20506386 |
Title : Insights into the fatty acid chain length specificity of the carboxylesterase PA3859 from Pseudomonas aeruginosa: A combined structural, biochemical and computational study - Pesaresi_2010_Biochimie_92_1787 |
Author(s) : Pesaresi A , Lamba D |
Ref : Biochimie , 92 :1787 , 2010 |
Abstract : Pesaresi_2010_Biochimie_92_1787 |
ESTHER : Pesaresi_2010_Biochimie_92_1787 |
PubMedSearch : Pesaresi_2010_Biochimie_92_1787 |
PubMedID: 20850500 |
Gene_locus related to this paper: pseae-PA3859 |
Title : Lipases for biotechnology - Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
Author(s) : Jaeger KE , Eggert T |
Ref : Curr Opin Biotechnol , 13 :390 , 2002 |
Abstract : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
ESTHER : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
PubMedSearch : Jaeger_2002_Curr.Opin.Biotechnol_13_390 |
PubMedID: 12323363 |
Title : Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A - Devedjiev_2000_Structure_8_1137 |
Author(s) : Devedjiev Y , Dauter Z , Kuznetsov SR , Jones TL , Derewenda ZS |
Ref : Structure , 8 :1137 , 2000 |
Abstract : Devedjiev_2000_Structure_8_1137 |
ESTHER : Devedjiev_2000_Structure_8_1137 |
PubMedSearch : Devedjiev_2000_Structure_8_1137 |
PubMedID: 11080636 |
Gene_locus related to this paper: human-LYPLA1 |
Title : Bacterial lipolytic enzymes: classification and properties - Arpigny_1999_Biochem.J_343_177 |
Author(s) : Arpigny JL , Jaeger KE |
Ref : Biochemical Journal , 343 :177 , 1999 |
Abstract : Arpigny_1999_Biochem.J_343_177 |
ESTHER : Arpigny_1999_Biochem.J_343_177 |
PubMedSearch : Arpigny_1999_Biochem.J_343_177 |
PubMedID: 10493927 |
Title : cDNA cloning and expression of a novel family of enzymes with calcium-independent phospholipase A2 and lysophospholipase activities - Portilla_1998_J.Am.Soc.Nephrol_9_1178 |
Author(s) : Portilla D , Crew MD , Grant D , Serrero G , Bates LM , Dai G , Sasner M , Cheng J , Buonanno A |
Ref : J Am Soc Nephrol , 9 :1178 , 1998 |
Abstract : Portilla_1998_J.Am.Soc.Nephrol_9_1178 |
ESTHER : Portilla_1998_J.Am.Soc.Nephrol_9_1178 |
PubMedSearch : Portilla_1998_J.Am.Soc.Nephrol_9_1178 |
PubMedID: 9644627 |
Gene_locus related to this paper: rabit-lypla1 , rabit-O77820 , ratno-lypla1a |
Title : Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha\/beta hydrolase with broad substrate specificity - Kim_1997_Structure_5_1571 |
Author(s) : Kim KK , Song HK , Shin DH , Hwang KY , Choe S , Yoo OJ , Suh SW |
Ref : Structure , 5 :1571 , 1997 |
Abstract : Kim_1997_Structure_5_1571 |
ESTHER : Kim_1997_Structure_5_1571 |
PubMedSearch : Kim_1997_Structure_5_1571 |
PubMedID: 9438866 |
Gene_locus related to this paper: psefl-cxest |
Structures (27)
Genes Proteins in LYsophospholipase_carboxylesterase family (350)
Fragments of genes in LYsophospholipase_carboxylesterase family (14)
Structures in LYsophospholipase_carboxylesterase family (27)Substrates in LYsophospholipase_carboxylesterase family (20)
Inhibitors in LYsophospholipase_carboxylesterase family (24)