rabit-1cxes
Oryctolagus cuniculus protein for liver 60 kD carboxylesterase 1
Comment
There are variant sequences from cDNA by Danks et al. EMBL AF036930: go to protein and WGFFSTGDEHSRGNWGHLDQVAAL -> GGFGFNIDELFLVAVN in Ozols. We included the sequence from the structure
Relationship
Family : Carb_B_Chordata
Block : C
Position in NCBI Life Tree : Oryctolagus cuniculus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Lagomorpha N E > Leporidae N E > Oryctolagus N E > Oryctolagus cuniculus N EMolecular evidence
Sequence
Peptide
MWLRALVLAT LAAFTAWGHP SSPPVVDTVH GKVLGKFVSL EGFAQPVAVF LGVPFAKPPL GSLRFAPPQP AESWSHVKNT TSYPPMCSQD AVSGHMLSEL FTNRKENIPL KFSEDCLYLN IYTPADLTKR GRLPVMVWIH GGGLMVGGAS TYDGLALSAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW VQDNIANFGG DPGSVTIFGE SAGGQSVSIL LLSPLTKNLF HRAISESGVA LLSSLFRKNT KSLAEKIAIE AGCKTTTSAV MVHCLRQKTE EELMEVTLKM KFMALDLVGD PKENTAFLTT VIDGVLLPKA PAEILAEKKY NMLPYMVGIN QQEFGWIIPM QMLGYPLSEG KLDQKTATEL LWKSYPIVNV SKELTPVATE KYLGGTDDPV KKKDLFLDML ADLLFGVPSV NVARHHRDAG APTYMYEYRY RPSFSSDMRP KTVIGDHGDE IFSVLGAPFL KEGATEEEIK LSKMVMKYWA NFARNGNPNG EGLPQWPAYD YKEGYLQIGA TTQAAQKLKD KEVAFWTELW AKEAARPRET EHIEL
References (5)
| Title : Structural insights into CPT-11 activation by mammalian carboxylesterases - Bencharit_2002_Nat.Struct.Biol_9_337 |
| Author(s) : Bencharit S , Morton CL , Howard-Williams EL , Danks MK , Potter PM , Redinbo MR |
| Ref : Nat Struct Biol , 9 :337 , 2002 |
| PubMedID: 11967565 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Overexpression of a rabbit liver carboxylesterase sensitizes human tumor cells to CPT-11 - Danks_1998_Cancer.Res_58_20 |
| Author(s) : Danks MK , Morton CL , Pawlik CA , Potter PM |
| Ref : Cancer Research , 58 :20 , 1998 |
| PubMedID: 9426050 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11) - Potter_1998_Cancer.Res_58_2646 |
| Author(s) : Potter PM , Pawlik CA , Morton CL , Naeve CW , Danks MK |
| Ref : Cancer Research , 58 :2646 , 1998 |
| PubMedID: 9635592 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Complete covalent structure of 60-kDa esterase isolated from 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced rabbit liver microsomes - Korza_1988_J.Biol.Chem_263_3486 |
| Author(s) : Korza G , Ozols J |
| Ref : Journal of Biological Chemistry , 263 :3486 , 1988 |
| PubMedID: 3343253 |
| Gene_locus related to this paper: rabit-1cxes |
| Title : Isolation and characterization of a 60-kilodalton glycoprotein esterase from liver microsomal membranes - Ozols_1987_J.Biol.Chem_262_15316 |
| Author(s) : Ozols J |
| Ref : Journal of Biological Chemistry , 262 (31) :15316 , 1987 |
| PubMedID: 3667634 |
| Gene_locus related to this paper: rabit-1cxes |