Tributyrin
General
Type : Water-soluble short chain ester, Acyl-Glycerol, Triacylglycerol
Chemical_Nomenclature : 2,3-di(butanoyloxy)propyl butanoate
Canonical SMILES : CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
InChI : InChI=1S\/C15H26O6\/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2\/h12H,4-11H2,1-3H3
InChIKey : UYXTWWCETRIEDR-UHFFFAOYSA-N
Other name(s) : C4-triglyceride || Glyceryl tributyrate || Glyceryl-tributyrate || Glyceril tributirate || Glyceril-tributirate || Glycerol tributyrate || Tributyrinine || Tributin || Butyryl triglyceride || Butanoic acid, 1,2,3-propanetriyl ester || Butyrin || Tri-n-butyrin || Glyceroltributyrin || 1,2,3-Tributyrylglycerol || 1,2,3-tributylglycerol || Butyrin, tri- || Tributyrl glyceride || Glycerin tributyrate || Tributyryl glyceride || Glycerol tributanoate || FEMA No. 2223 || HSDB 878 || 1,2,3-Propanetriyl tributanoate || Butyric acid triester with glycerin || EINECS 200-451-5 || NSC661583 || NSC 661583 || BRN 1714746 || AI3-01776 || 1,3-Tributyrylglycerol || AC1L1LP0 || UNII-S05LZ624MF || T8626_SIGMA || W222305_ALDRICH || 113026_ALDRICH || AC1Q63D4 || CHEMBL118722 || 2,3-Bis(butyryloxy)propyl butyrate || 2,3-di(butanoyloxy)propyl butanoate || ANW-13576 || AR-1L7114 || CPD-13014 || ZINC03860906 || AKOS015903304 || NSC-661583 || LS-48211 || NCI60_021427 || T0364 || C13870 || 4-02-00-00799 (Beilstein Handbook Reference)
MW : 302.36334
Formula : C15H26O6
CAS_number : 60-01-5
PubChem : 6050
UniChem : UYXTWWCETRIEDR-UHFFFAOYSA-N
Wikipedia : Tributyrin
Target
Families : Acidic_Lipase, Cutinase, Lipase_3, CarbLipBact_2, Bacterial_lip_FamI.3, Bacterial_lip_FamI.5, Lipase_bact_N_lipase, Lipase_2, Fungal_carboxylesterase_lipase, Pancreatic_lipase, Cholesterol_esterase, Carb_B_Chordata, Bacterial_lip_FamI.1, Canar_LipB, Fungal-Bact_LIP, Bacterial_lip_FamI.6, 6_AlphaBeta_hydrolase
References (15)
| Title : Monomeric Esterase: Insights into Cooperative Behavior, Hysteresis\/Allokairy - Vinces_2024_Biochemistry_63_1178 |
| Author(s) : Vinces TC , de Souza AS , Carvalho CF , Visnardi AB , Teixeira RD , Llontop EE , Bismara BAP , Vicente EJ , Pereira JO , de Souza RF , Yonamine M , Marana SR , Farah CS , Guzzo CR |
| Ref : Biochemistry , 63 :1178 , 2024 |
| Abstract : |
| PubMedSearch : Vinces_2024_Biochemistry_63_1178 |
| PubMedID: 38669355 |
| Gene_locus related to this paper: 9bact-6EB3 |
| Title : An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases - Jung_2021_J.Biol.Eng_15_9 |
| Author(s) : Jung DH , Yong JH , Hwang W , Yoon MY , Yoon SS |
| Ref : J Biol Eng , 15 :9 , 2021 |
| Abstract : |
| PubMedSearch : Jung_2021_J.Biol.Eng_15_9 |
| PubMedID: 33676548 |
| Title : Principles of lipid-enzyme interactions in the limbus region of the catalytic site of Candida antarctica Lipase B - Silvestrini_2020_Int.J.Biol.Macromol_158_358 |
| Author(s) : Silvestrini L , Cianci M |
| Ref : Int J Biol Macromol , 158 :358 , 2020 |
| Abstract : |
| PubMedSearch : Silvestrini_2020_Int.J.Biol.Macromol_158_358 |
| PubMedID: 32380114 |
| Gene_locus related to this paper: canar-LipB |
| Title : The beta5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2) - Xiao_2015_J.Biol.Chem_290_28847 |
| Author(s) : Xiao X , Lowe ME |
| Ref : Journal of Biological Chemistry , 290 :28847 , 2015 |
| Abstract : |
| PubMedSearch : Xiao_2015_J.Biol.Chem_290_28847 |
| PubMedID: 26494624 |
| Gene_locus related to this paper: human-PNLIP , human-PNLIPRP2 |
| Title : The galactolipase activity of some microbial lipases and pancreatic enzymes - Amara_2013_Eur.J.Lipid.Sci.Technol_115_442 |
| Author(s) : Amara S , Lafont D , Parsiegla G , Point V , Chabannes A , Rousset A , Carriere F |
| Ref : Eur J Lipid Sci Technol , 115 :442 , 2013 |
| Abstract : |
| PubMedSearch : Amara_2013_Eur.J.Lipid.Sci.Technol_115_442 |
| PubMedID: |
| Gene_locus related to this paper: bovin-balip , human-CEL |
| Title : Non-lipolytic and lipolytic sequence-related carboxylesterases: a comparative study of the structure-function relationships of rabbit liver esterase 1 and bovine pancreatic bile-salt-activated lipase - Chahinian_2010_Biochim.Biophys.Acta_1801_1195 |
| Author(s) : Chahinian H , Fantini J , Garmy N , Manco G , Sarda L |
| Ref : Biochimica & Biophysica Acta , 1801 :1195 , 2010 |
| Abstract : |
| PubMedSearch : Chahinian_2010_Biochim.Biophys.Acta_1801_1195 |
| PubMedID: 20655391 |
| Title : Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation - Eydoux_2008_Biochemistry_47_9553 |
| Author(s) : Eydoux C , Spinelli S , Davis TL , Walker JR , Seitova A , Dhe-Paganon S , de Caro A , Cambillau C , Carriere F |
| Ref : Biochemistry , 47 :9553 , 2008 |
| Abstract : |
| PubMedSearch : Eydoux_2008_Biochemistry_47_9553 |
| PubMedID: 18702514 |
| Gene_locus related to this paper: human-PNLIPRP2 |
| Title : Structural insights into the lipase\/esterase behavior in the Candida rugosa lipases family: crystal structure of the lipase 2 isoenzyme at 1.97A resolution - Mancheno_2003_J.Mol.Biol_332_1059 |
| Author(s) : Mancheno JM , Pernas MA , Martinez MJ , Ochoa B , Rua ML , Hermoso JA |
| Ref : Journal of Molecular Biology , 332 :1059 , 2003 |
| Abstract : |
| PubMedSearch : Mancheno_2003_J.Mol.Biol_332_1059 |
| PubMedID: 14499609 |
| Gene_locus related to this paper: canru-2lipa |
| Title : A novel extracellular esterase from Bacillus subtilis and its conversion to a monoacylglycerol hydrolase - Eggert_2000_Eur.J.Biochem_267_6459 |
| Author(s) : Eggert T , Pencreac'h G , Douchet I , Verger R , Jaeger KE |
| Ref : European Journal of Biochemistry , 267 :6459 , 2000 |
| Abstract : |
| PubMedSearch : Eggert_2000_Eur.J.Biochem_267_6459 |
| PubMedID: 11029590 |
| Gene_locus related to this paper: bacsu-LIPB |
| Title : Staphylococcus haemolyticus lipase: biochemical properties, substrate specificity and gene cloning - Oh_1999_FEMS.Microbiol.Lett_179_385 |
| Author(s) : Oh B , Kim H , Lee J , Kang S , Oh T |
| Ref : FEMS Microbiology Letters , 179 :385 , 1999 |
| Abstract : |
| PubMedSearch : Oh_1999_FEMS.Microbiol.Lett_179_385 |
| PubMedID: 10518741 |
| Gene_locus related to this paper: staha-Q9RGZ6 |
| Title : Purification and molecular cloning of porcine intestinal glycerol-ester hydrolase--evidence for its identity with carboxylesterase - David_1998_Eur.J.Biochem_257_142 |
| Author(s) : David L , Guo XJ , Villard C , Moulin A , Puigserver A |
| Ref : European Journal of Biochemistry , 257 :142 , 1998 |
| Abstract : |
| PubMedSearch : David_1998_Eur.J.Biochem_257_142 |
| PubMedID: 9799112 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Purification and biochemical characterization of dog gastric lipase - Carriere_1991_Eur.J.Biochem_202_75 |
| Author(s) : Carriere F , Moreau H , Raphel V , Laugier R , Benicourt C , Junien JL , Verger R |
| Ref : European Journal of Biochemistry , 202 :75 , 1991 |
| Abstract : |
| PubMedSearch : Carriere_1991_Eur.J.Biochem_202_75 |
| PubMedID: 1935982 |
| Gene_locus related to this paper: canfa-1lipg |
| Title : Purification, characterization and kinetic properties of the rabbit gastric lipase - Moreau_1988_Biochim.Biophys.Acta_960_286 |
| Author(s) : Moreau H , Gargouri Y , Lecat D , Junien JL , Verger R |
| Ref : Biochimica & Biophysica Acta , 960 :286 , 1988 |
| Abstract : |
| PubMedSearch : Moreau_1988_Biochim.Biophys.Acta_960_286 |
| PubMedID: 3382677 |
| Title : Kinetic assay of human gastric lipase on short- and long-chain triacylglycerol emulsions - Gargouri_1986_Gastroenterology_91_919 |
| Author(s) : Gargouri Y , Pieroni G , Riviere C , Sauniere JF , Lowe PA , Sarda L , Verger R |
| Ref : Gastroenterology , 91 :919 , 1986 |
| Abstract : |
| PubMedSearch : Gargouri_1986_Gastroenterology_91_919 |
| PubMedID: 3743968 |