Title : Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity - Zhang_2019_J.Med.Chem_62_8532 |
Author(s) : Zhang L , Butler CR , Maresca KP , Takano A , Nag S , Jia Z , Arakawa R , Piro JR , Samad T , Smith DL , Nason DM , O'Neil S , McAllister L , Schildknegt K , Trapa P , McCarthy TJ , Villalobos A , Halldin C |
Ref : Journal of Medicinal Chemistry , 62 :8532 , 2019 |
Abstract : |
PubMedSearch : Zhang_2019_J.Med.Chem_62_8532 |
PubMedID: 31483137 |
Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
Abstract : |
PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
PubMedID: 29498843 |
Gene_locus related to this paper: human-MGLL |
Title : Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase - Butler_2017_J.Med.Chem_60_9860 |
Author(s) : Butler CR , Beck EM , Harris A , Huang Z , McAllister LA , Am Ende CW , Fennell K , Foley TL , Fonseca K , Hawrylik SJ , Johnson DS , Knafels JD , Mente S , Noell GS , Pandit J , Phillips TB , Piro JR , Rogers BN , Samad TA , Wang J , Wan S , Brodney MA |
Ref : Journal of Medicinal Chemistry , 60 :9860 , 2017 |
Abstract : |
PubMedSearch : Butler_2017_J.Med.Chem_60_9860 |
PubMedID: 29148769 |
Gene_locus related to this paper: human-MGLL |