| Title : The Synthesis of Certain Derivatives and Analogues of (-)- and (+)-Galanthamine and an Assessment of their Capacities to Inhibit Acetylcholine Esterase - Buckler_2017_J.Org.Chem_82_7869 |
| Author(s) : Buckler JN , Taher ES , Fraser NJ , Willis AC , Carr PD , Jackson CJ , Banwell MG |
| Ref : J Org Chem , 82 :7869 , 2017 |
| Abstract : |
| PubMedSearch : Buckler_2017_J.Org.Chem_82_7869 |
| PubMedID: 28671462 |
| Title : Structure of an Insecticide Sequestering Carboxylesterase from the Disease Vector Culex quinquefasciatus: What Makes an Enzyme a Good Insecticide Sponge? - Hopkins_2017_Biochemistry_56_5512 |
| Author(s) : Hopkins DH , Fraser NJ , Mabbitt PD , Carr PD , Oakeshott JG , Jackson CJ |
| Ref : Biochemistry , 56 :5512 , 2017 |
| Abstract : |
| PubMedSearch : Hopkins_2017_Biochemistry_56_5512 |
| PubMedID: 28929747 |
| Gene_locus related to this paper: culqu-1estb |
| Title : Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography - Correy_2016_Structure_24_977 |
| Author(s) : Correy GJ , Carr PD , Meirelles T , Mabbitt PD , Fraser NJ , Weik M , Jackson CJ |
| Ref : Structure , 24 :977 , 2016 |
| Abstract : |
| PubMedSearch : Correy_2016_Structure_24_977 |
| PubMedID: 27210287 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : The role of protein dynamics in the evolution of new enzyme function - Campbell_2016_Nat.Chem.Biol_12_944 |
| Author(s) : Campbell EC , Kaltenbach M , Correy GJ , Carr PD , Porebski BT , Livingstone EK , Afriat-Jurnou L , Buckle AM , Weik M , Hollfelder F , Tokuriki N , Jackson CJ |
| Ref : Nat Chemical Biology , 12 :944 , 2016 |
| Abstract : |
| PubMedSearch : Campbell_2016_Nat.Chem.Biol_12_944 |
| PubMedID: 27618189 |
| Title : Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron - Sugrue_2015_Appl.Environ.Microbiol_81_2612 |
| Author(s) : Sugrue E , Fraser NJ , Hopkins DH , Carr PD , Khurana JL , Oakeshott JG , Scott C , Jackson CJ |
| Ref : Applied Environmental Microbiology , 81 :2612 , 2015 |
| Abstract : |
| PubMedSearch : Sugrue_2015_Appl.Environ.Microbiol_81_2612 |
| PubMedID: 25636851 |
| Title : Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing - Porter_2014_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_70_884 |
| Author(s) : Porter JL , Carr PD , Collyer CA , Ollis DL |
| Ref : Acta Crystallographica F Struct Biol Commun , 70 :884 , 2014 |
| Abstract : |
| PubMedSearch : Porter_2014_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_70_884 |
| PubMedID: 25005082 |
| Gene_locus related to this paper: psepu-clcd1 |
| Title : A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis - Naqvi_2014_PLoS.One_9_e94177 |
| Author(s) : Naqvi T , Warden AC , French N , Sugrue E , Carr PD , Jackson CJ , Scott C |
| Ref : PLoS ONE , 9 :e94177 , 2014 |
| Abstract : |
| PubMedSearch : Naqvi_2014_PLoS.One_9_e94177 |
| PubMedID: 24721933 |
| Title : Structure and function of an insect alpha-carboxylesterase (alphaEsterase7) associated with insecticide resistance - Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| Author(s) : Jackson CJ , Liu JW , Carr PD , Younus F , Coppin C , Meirelles T , Lethier M , Pandey G , Ollis DL , Russell RJ , Weik M , Oakeshott JG |
| Ref : Proc Natl Acad Sci U S A , 110 :10177 , 2013 |
| Abstract : |
| PubMedSearch : Jackson_2013_Proc.Natl.Acad.Sci.U.S.A_110_10177 |
| PubMedID: 23733941 |
| Gene_locus related to this paper: luccu-E3aest7 |
| Title : Alpha\/beta hydrolase fold: an update - Carr_2009_Protein.Pept.Lett_16_1137 |
| Author(s) : Carr PD , Ollis DL |
| Ref : Protein Pept Lett , 16 :1137 , 2009 |
| Abstract : |
| PubMedSearch : Carr_2009_Protein.Pept.Lett_16_1137 |
| PubMedID: 19508187 |
| Title : In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase - Jackson_2008_J.Mol.Biol_375_1189 |
| Author(s) : Jackson CJ , Foo JL , Kim HK , Carr PD , Liu JW , Salem G , Ollis DL |
| Ref : Journal of Molecular Biology , 375 :1189 , 2008 |
| Abstract : |
| PubMedSearch : Jackson_2008_J.Mol.Biol_375_1189 |
| PubMedID: 18082180 |
| Title : Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase - Kim_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_920 |
| Author(s) : Kim HK , Liu JW , Carr PD , Ollis DL |
| Ref : Acta Crystallographica D Biol Crystallogr , 61 :920 , 2005 |
| Abstract : |
| PubMedSearch : Kim_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_920 |
| PubMedID: 15983415 |
| Gene_locus related to this paper: psepu-clcd1 |
| Title : Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution - Yang_2003_Protein.Eng_16_135 |
| Author(s) : Yang H , Carr PD , McLoughlin SY , Liu JW , Horne I , Qiu X , Jeffries CM , Russell RJ , Oakeshott JG , Ollis DL |
| Ref : Protein Engineering , 16 :135 , 2003 |
| Abstract : |
| PubMedSearch : Yang_2003_Protein.Eng_16_135 |
| PubMedID: 12676982 |
| Title : Expression, purification and preliminary crystallographic studies of a hyperthermophilic esterase from Archaeoglobus fulgidus - Liu_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_900 |
| Author(s) : Liu JW , Verger D , Carr PD , Yang H , Ollis DL |
| Ref : Acta Crystallographica D Biol Crystallogr , 56 :900 , 2000 |
| Abstract : |
| PubMedSearch : Liu_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_900 |
| PubMedID: 10930838 |
| Title : Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF) - Robinson_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1376 |
| Author(s) : Robinson A , Edwards KJ , Carr PD , Barton JD , Ewart GD , Ollis DL |
| Ref : Acta Crystallographica D Biol Crystallogr , 56 :1376 , 2000 |
| Abstract : |
| PubMedSearch : Robinson_2000_Acta.Crystallogr.D.Biol.Crystallogr_56_1376 |
| PubMedID: 11053834 |
| Gene_locus related to this paper: psepu-clcd1 |