| Title : Ultrahigh-throughput directed evolution of a metal-free alpha\/beta-hydrolase with a Cys-His-Asp triad into an efficient phosphotriesterase - Schnettler-Fernandez_2022_Biorxiv__ |
| Author(s) : Schnettler-Fernandez D , Klein OJ , Kaminski TS , Colin PY , Hollfelder F |
| Ref : Biorxiv , : , 2022 |
| Abstract : |
| PubMedSearch : Schnettler-Fernandez_2022_Biorxiv__ |
| PubMedID: |
| Gene_locus related to this paper: 9bact-KP212148 |
| Title : Ultrahigh-Throughput Directed Evolution of a Metal-Free alpha\/beta-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase - Schnettler_2022_J.Am.Chem.Soc__ |
| Author(s) : Schnettler JD , Klein OJ , Kaminski TS , Colin PY , Hollfelder F |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : |
| PubMedSearch : Schnettler_2022_J.Am.Chem.Soc__ |
| PubMedID: 36583539 |
| Gene_locus related to this paper: 9bact-KP212148 |
| Title : Adventures on the routes of protein evolution - in memoriam Dan Salah Tawfik (1955 - 2021) - Jackson_2022_J.Mol.Biol_434_167462 |
| Author(s) : Jackson C , Toth-Petroczy A , Kolodny R , Hollfelder F , Fuxreiter M , Caroline Lynn Kamerlin S , Tokuriki N |
| Ref : Journal of Molecular Biology , :167462 , 2022 |
| Abstract : |
| PubMedSearch : Jackson_2022_J.Mol.Biol_434_167462 |
| PubMedID: 35104498 |
| Title : Engineering the protein dynamics of an ancestral luciferase - Schenkmayerova_2021_Nat.Commun_12_3616 |
| Author(s) : Schenkmayerova A , Pinto GP , Toul M , Marek M , Hernychova L , Planas-Iglesias J , Daniel Liskova V , Pluskal D , Vasina M , Emond S , Dorr M , Chaloupkova R , Bednar D , Prokop Z , Hollfelder F , Bornscheuer UT , Damborsky J |
| Ref : Nat Commun , 12 :3616 , 2021 |
| Abstract : |
| PubMedSearch : Schenkmayerova_2021_Nat.Commun_12_3616 |
| PubMedID: 34127663 |
| Gene_locus related to this paper: renre-luc |
| Title : Engineering Protein Dynamics of Ancestral Luciferase - Schenkmayerova_2020_Chemrxiv__ |
| Author(s) : Schenkmayerova A , Pinto GP , Toul M , Marek M , Hernychova L , Planas-Iglesias J , Liskova V , Pluskal D , Vasina M , Emond S , Dorr M , Chaloupkova R , Bednar D , Prokop Z , Hollfelder F , Bornscheuer UT , Damborsky J |
| Ref : Chemrxiv , : , 2020 |
| Abstract : |
| PubMedSearch : Schenkmayerova_2020_Chemrxiv__ |
| PubMedID: |
| Gene_locus related to this paper: renre-luc |
| Title : Controlled Oil\/Water Partitioning of Hydrophobic Substrates Extending the Bioanalytical Applications of Droplet-Based Microfluidics - Buryska_2019_Anal.Chem_91_10008 |
| Author(s) : Buryska T , Vasina M , Gielen F , Vanacek P , van Vliet L , Jezek J , Pilat Z , Zemanek P , Damborsky J , Hollfelder F , Prokop Z |
| Ref : Analytical Chemistry , 91 :10008 , 2019 |
| Abstract : |
| PubMedSearch : Buryska_2019_Anal.Chem_91_10008 |
| PubMedID: 31240908 |
| Title : Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase - van Loo_2019_Biochemistry_58_1363 |
| Author(s) : van Loo B , Berry R , Boonyuen U , Mohamed MF , Golicnik M , Hengge AC , Hollfelder F |
| Ref : Biochemistry , 58 :1363 , 2019 |
| Abstract : |
| PubMedSearch : van Loo_2019_Biochemistry_58_1363 |
| PubMedID: 30810299 |
| Title : Specificity Effects of Amino Acid Substitutions in Promiscuous Hydrolases: Context-Dependence of Catalytic Residue Contributions to Local Fitness Landscapes in Nearby Sequence Space - Bayer_2017_Chembiochem_18_1001 |
| Author(s) : Bayer CD , van Loo B , Hollfelder F |
| Ref : Chembiochem , 18 :1001 , 2017 |
| Abstract : |
| PubMedSearch : Bayer_2017_Chembiochem_18_1001 |
| PubMedID: 28464395 |
| Title : Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity - Kaltenbach_2016_PLoS.Genet_12_e1006305 |
| Author(s) : Kaltenbach M , Emond S , Hollfelder F , Tokuriki N |
| Ref : PLoS Genet , 12 :e1006305 , 2016 |
| Abstract : |
| PubMedSearch : Kaltenbach_2016_PLoS.Genet_12_e1006305 |
| PubMedID: 27716796 |
| Title : The role of protein dynamics in the evolution of new enzyme function - Campbell_2016_Nat.Chem.Biol_12_944 |
| Author(s) : Campbell EC , Kaltenbach M , Correy GJ , Carr PD , Porebski BT , Livingstone EK , Afriat-Jurnou L , Buckle AM , Weik M , Hollfelder F , Tokuriki N , Jackson CJ |
| Ref : Nat Chemical Biology , 12 :944 , 2016 |
| Abstract : |
| PubMedSearch : Campbell_2016_Nat.Chem.Biol_12_944 |
| PubMedID: 27618189 |
| Title : Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics - Colin_2015_Nat.Commun_6_10008 |
| Author(s) : Colin PY , Kintses B , Gielen F , Miton CM , Fischer G , Mohamed MF , Hyvonen M , Morgavi DP , Janssen DB , Hollfelder F |
| Ref : Nat Commun , 6 :10008 , 2015 |
| Abstract : |
| PubMedSearch : Colin_2015_Nat.Commun_6_10008 |
| PubMedID: 26639611 |
| Gene_locus related to this paper: 9bact-KP212148 |
| Title : Handicap-Recover Evolution Leads to a Chemically Versatile, Nucleophile-Permissive Protease - Shafee_2015_Chembiochem_16_1866 |
| Author(s) : Shafee T , Gatti-Lafranconi P , Minter R , Hollfelder F |
| Ref : Chembiochem , 16 :1866 , 2015 |
| Abstract : |
| PubMedSearch : Shafee_2015_Chembiochem_16_1866 |
| PubMedID: 26097079 |
| Title : Evolution of enzyme catalysts caged in biomimetic gel-shell beads - Fischlechner_2014_Nat.Chem_6_791 |
| Author(s) : Fischlechner M , Schaerli Y , Mohamed MF , Patil S , Abell C , Hollfelder F |
| Ref : Nat Chem , 6 :791 , 2014 |
| Abstract : |
| PubMedSearch : Fischlechner_2014_Nat.Chem_6_791 |
| PubMedID: 25143214 |
| Title : Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology - Theberge_2010_Angew.Chem.Int.Ed.Engl_49_5846 |
| Author(s) : Theberge AB , Courtois F , Schaerli Y , Fischlechner M , Abell C , Hollfelder F , Huck WT |
| Ref : Angew Chem Int Ed Engl , 49 :5846 , 2010 |
| Abstract : |
| PubMedSearch : Theberge_2010_Angew.Chem.Int.Ed.Engl_49_5846 |
| PubMedID: 20572214 |
| Title : New genotype-phenotype linkages for directed evolution of functional proteins - Leemhuis_2005_Curr.Opin.Struct.Biol_15_472 |
| Author(s) : Leemhuis H , Stein V , Griffiths AD , Hollfelder F |
| Ref : Current Opinion in Structural Biology , 15 :472 , 2005 |
| Abstract : |
| PubMedSearch : Leemhuis_2005_Curr.Opin.Struct.Biol_15_472 |
| PubMedID: 16043338 |