| Title : Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain - Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| Author(s) : Codony S , Jora B , Santos-Caballero M , Qiu Q , Calvo-Tusell C , Escriche C , Turcu AL , Prischi F , Bartra C , Val C , Morisseau C , Perez B , Bertran-Mostazo A , Osuna S , Corpas R , Grinan-Ferre C , Galdeano C , Loza MI , Pallas M , Sanfeliu C , Hammock BD , Brea J , Feixas F , Conte MR , Cobos EJ , Vazquez S |
| Ref : J Enzyme Inhib Med Chem , 40 :2574990 , 2025 |
| Abstract : |
| PubMedSearch : Codony_2025_J.Enzyme.Inhib.Med.Chem_40_2574990 |
| PubMedID: 41128518 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Soluble Epoxide Hydrolase Inhibition Improves Alzheimer's Disease Hallmarks: Correlation with Peripheral Inflammation and Gut Microbiota Modulation - Jarne-Ferrer_2025_Aging.Dis__ |
| Author(s) : Jarne-Ferrer J , Grinan-Ferre C , Jora B , Codony S , Miro L , Rosell-Cardona C , Minana-Galbis D , Perez-Bosque A , Vazquez S , Pallas M |
| Ref : Aging Dis , : , 2025 |
| Abstract : |
| PubMedSearch : Jarne-Ferrer_2025_Aging.Dis__ |
| PubMedID: 40423637 |
| Title : Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies - Jarne-Ferrer_2025_ACS.Pharmacol.Transl.Sci_8_533 |
| Author(s) : Jarne-Ferrer J , Sanchez J , Codony S , Schneider M , Muller CE , Sanfeliu C , Franco R , Vazquez S , Grinan-Ferre C , Pallas M |
| Ref : ACS Pharmacol Transl Sci , 8 :533 , 2025 |
| Abstract : |
| PubMedSearch : Jarne-Ferrer_2025_ACS.Pharmacol.Transl.Sci_8_533 |
| PubMedID: 39974649 |
| Title : Microglial pro-inflammatory mechanisms induced by monomeric C-reactive protein are counteracted by soluble epoxide hydrolase inhibitors - Bartra_2025_Int.Immunopharmacol_155_114644 |
| Author(s) : Bartra C , Vuraic K , Yuan Y , Codony S , Valdes-Quiroz H , Casal C , Slevin M , Maquez-Kisinousky L , Planas AM , Grinan-Ferre C , Pallas M , Morisseau C , Hammock BD , Vazquez S , Sunol C , Sanfeliu C |
| Ref : Int Immunopharmacol , 155 :114644 , 2025 |
| Abstract : |
| PubMedSearch : Bartra_2025_Int.Immunopharmacol_155_114644 |
| PubMedID: 40215773 |
| Title : Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics - Grinan-Ferre_2023_CNS.Neurosci.Ther__ |
| Author(s) : Grinan-Ferre C , Jarne-Ferrer J , Bellver-Sanchis A , Codony S , Puigoriol-Illamola D , Sanfeliu C , Oh Y , Lee S , Vazquez S , Pallas M |
| Ref : CNS Neurosci Ther , : , 2023 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2023_CNS.Neurosci.Ther__ |
| PubMedID: 37905690 |
| Title : Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Codony_2022_J.Med.Chem_65_4909 |
| Author(s) : Codony S , Pont C , Grinan-Ferre C , Di Pede-Mattatelli A , Calvo-Tusell C , Feixas F , Osuna S , Jarne-Ferrer J , Naldi M , Bartolini M , Loza MI , Brea J , Perez B , Bartra C , Sanfeliu C , Juarez-Jimenez J , Morisseau C , Hammock BD , Pallas M , Vazquez S , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 65 :4909 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_4909 |
| PubMedID: 35271276 |
| Title : Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors - Codony_2022_J.Med.Chem_65_13660 |
| Author(s) : Codony S , Entrena JM , Calvo-Tusell C , Jora B , Gonzalez-Cano R , Osuna S , Corpas R , Morisseau C , Perez B , Barniol-Xicota M , Grinan-Ferre C , Perez C , Rodriguez-Franco MI , Martinez AL , Loza MI , Pallas M , Verhelst SHL , Sanfeliu C , Feixas F , Hammock BD , Brea J , Cobos EJ , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 65 :13660 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_13660 |
| PubMedID: 36222708 |
| Title : Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer's Disease Neurodegeneration - Bartra_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Bartra C , Irisarri A , Villoslada A , Corpas R , Aguirre S , Garcia-Lara E , Sunol C , Pallas M , Grinan-Ferre C , Sanfeliu C |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Bartra_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 36499477 |
| Title : A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer's Disease Mice Models - Jarne-Ferrer_2022_Pharmaceuticals.(Basel)_15_ |
| Author(s) : Jarne-Ferrer J , Grinan-Ferre C , Bellver-Sanchis A , Vazquez S , Munoz-Torrero D , Pallas M |
| Ref : Pharmaceuticals (Basel) , 15 : , 2022 |
| Abstract : |
| PubMedSearch : Jarne-Ferrer_2022_Pharmaceuticals.(Basel)_15_ |
| PubMedID: 35893732 |
| Title : Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: A Comparative study with donepezil - Vasilopoulou_2021_Br.J.Pharmacol__ |
| Author(s) : Vasilopoulou F , Rodriguez-Arevalo S , Bagan A , Escolano C , Grinan-Ferre C , Pallas M |
| Ref : British Journal of Pharmacology , : , 2021 |
| Abstract : |
| PubMedSearch : Vasilopoulou_2021_Br.J.Pharmacol__ |
| PubMedID: 33817786 |
| Title : From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects - Pont_2021_Eur.J.Med.Chem_225_113779 |
| Author(s) : Pont C , Ginex T , Grinan-Ferre C , Scheiner M , Mattellone A , Martinez N , Arce EM , Soriano-Fernandez Y , Naldi M , De Simone A , Barenys M , Gomez-Catalan J , Perez B , Sabate R , Andrisano V , Loza MI , Brea J , Bartolini M , Bolognesi ML , Decker M , Pallas M , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113779 , 2021 |
| Abstract : |
| PubMedSearch : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedID: 34418785 |
| Title : Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease - Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Grinan-Ferre C , Companys-Alemany J , Jarne-Ferrer J , Codony S , Gonzalez-Castillo C , Ortuno-Sahagun D , Vilageliu L , Grinberg D , Vazquez S , Pallas M |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33810307 |
| Title : From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis - Codony_2021_J.Med.Chem__ |
| Author(s) : Codony S , Calvo-Tusell C , Valverde E , Osuna S , Morisseau C , Loza MI , Brea J , Perez C , Rodriguez-Franco MI , Pizarro-Delgado J , Corpas R , Grinan-Ferre C , Pallas M , Sanfeliu C , Vazquez-Carrera M , Hammock BD , Feixas F , Vazquez S |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Codony_2021_J.Med.Chem__ |
| PubMedID: 33945278 |
| Title : Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy - Pallas_2020_Biomolecules_10_ |
| Author(s) : Pallas M , Vazquez S , Sanfeliu C , Galdeano C , Grinan-Ferre C |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Pallas_2020_Biomolecules_10_ |
| PubMedID: 32369955 |
| Title : Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease - Grinan-Ferre_2020_Neurotherapeutics__ |
| Author(s) : Grinan-Ferre C , Codony S , Pujol E , Yang J , Leiva R , Escolano C , Puigoriol-Illamola D , Companys-Alemany J , Corpas R , Sanfeliu C , Perez B , Loza MI , Brea J , Morisseau C , Hammock BD , Vazquez S , Pallas M , Galdeano C |
| Ref : Neurotherapeutics , : , 2020 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2020_Neurotherapeutics__ |
| PubMedID: 32488482 |