| Title : Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase - Casadevall_2023_bioRxiv__ |
| Author(s) : Casadevall G , Pierce C , Guan B , Iglesias-Fernandez J , Lim HY , Greenberg LR , Walsh ME , Shi K , Gordon W , Aihara H , Evans RL , Kazlauskas R , Osuna S |
| Ref : Biorxiv , : , 2023 |
| Abstract : |
| PubMedSearch : Casadevall_2023_bioRxiv__ |
| PubMedID: 37662272 |
| Gene_locus related to this paper: hevbr-hnl |
| Title : Brave new surfactant world revisited by thermoalkalophilic lipases: computational insights into the role of SDS as a substrate analog - Shehata_2023_Phys.Chem.Chem.Phys__ |
| Author(s) : Shehata M , Unlu A , Iglesias-Fernandez J , Osuna S , Sezerman OU , Timucin E |
| Ref : Phys Chem Chem Phys , : , 2023 |
| Abstract : |
| PubMedSearch : Shehata_2023_Phys.Chem.Chem.Phys__ |
| PubMedID: 36594810 |
| Title : Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors - Codony_2022_J.Med.Chem_65_13660 |
| Author(s) : Codony S , Entrena JM , Calvo-Tusell C , Jora B , Gonzalez-Cano R , Osuna S , Corpas R , Morisseau C , Perez B , Barniol-Xicota M , Grinan-Ferre C , Perez C , Rodriguez-Franco MI , Martinez AL , Loza MI , Pallas M , Verhelst SHL , Sanfeliu C , Feixas F , Hammock BD , Brea J , Cobos EJ , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 65 :13660 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_13660 |
| PubMedID: 36222708 |
| Title : Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Codony_2022_J.Med.Chem_65_4909 |
| Author(s) : Codony S , Pont C , Grinan-Ferre C , Di Pede-Mattatelli A , Calvo-Tusell C , Feixas F , Osuna S , Jarne-Ferrer J , Naldi M , Bartolini M , Loza MI , Brea J , Perez B , Bartra C , Sanfeliu C , Juarez-Jimenez J , Morisseau C , Hammock BD , Pallas M , Vazquez S , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 65 :4909 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_4909 |
| PubMedID: 35271276 |
| Title : From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis - Codony_2021_J.Med.Chem__ |
| Author(s) : Codony S , Calvo-Tusell C , Valverde E , Osuna S , Morisseau C , Loza MI , Brea J , Perez C , Rodriguez-Franco MI , Pizarro-Delgado J , Corpas R , Grinan-Ferre C , Pallas M , Sanfeliu C , Vazquez-Carrera M , Hammock BD , Feixas F , Vazquez S |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Codony_2021_J.Med.Chem__ |
| PubMedID: 33945278 |
| Title : 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis - Codony_2020_J.Med.Chem_63_9237 |
| Author(s) : Codony S , Pujol E , Pizarro J , Feixas F , Valverde E , Loza MI , Brea JM , Saez E , Oyarzabal J , Pineda-Lucena A , Perez B , Perez C , Rodriguez-Franco MI , Leiva R , Osuna S , Morisseau C , Hammock BD , Vazquez-Carrera M , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 63 :9237 , 2020 |
| Abstract : |
| PubMedSearch : Codony_2020_J.Med.Chem_63_9237 |
| PubMedID: 32787085 |
| Title : Intrinsic enzymatic properties modulate the self-propulsion of micromotors - Arque_2019_Nat.Commun_10_2826 |
| Author(s) : Arque X , Romero-Rivera A , Feixas F , Patino T , Osuna S , Sanchez S |
| Ref : Nat Commun , 10 :2826 , 2019 |
| Abstract : |
| PubMedSearch : Arque_2019_Nat.Commun_10_2826 |
| PubMedID: 31249381 |
| Title : Epoxide Hydrolase Conformational Heterogeneity for the Resolution of Bulky Pharmacologically Relevant Epoxide Substrates - Serrano-Hervas_2018_Chemistry_24_12254 |
| Author(s) : Serrano-Hervas E , Casadevall G , Garcia-Borras M , Feixas F , Osuna S |
| Ref : Chemistry , 24 :12254 , 2018 |
| Abstract : |
| PubMedSearch : Serrano-Hervas_2018_Chemistry_24_12254 |
| PubMedID: 29633396 |
| Title : Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium - Serrano-Hervas_2017_Org.Biomol.Chem_15_8827 |
| Author(s) : Serrano-Hervas E , Garcia-Borras M , Osuna S |
| Ref : Org Biomol Chem , 15 :8827 , 2017 |
| Abstract : |
| PubMedSearch : Serrano-Hervas_2017_Org.Biomol.Chem_15_8827 |
| PubMedID: 29026902 |