| Title : Novel Soluble Epoxide Hydrolase Inhibitor: Toward Regulatory Preclinical Studies - Jarne-Ferrer_2025_ACS.Pharmacol.Transl.Sci_8_533 |
| Author(s) : Jarne-Ferrer J , Sanchez J , Codony S , Schneider M , Muller CE , Sanfeliu C , Franco R , Vazquez S , Grinan-Ferre C , Pallas M |
| Ref : ACS Pharmacol Transl Sci , 8 :533 , 2025 |
| Abstract : |
| PubMedSearch : Jarne-Ferrer_2025_ACS.Pharmacol.Transl.Sci_8_533 |
| PubMedID: 39974649 |
| Title : Novel molecular mechanism driving neuroprotection after soluble epoxide hydrolase inhibition: Insights for Alzheimer's disease therapeutics - Grinan-Ferre_2023_CNS.Neurosci.Ther__ |
| Author(s) : Grinan-Ferre C , Jarne-Ferrer J , Bellver-Sanchis A , Codony S , Puigoriol-Illamola D , Sanfeliu C , Oh Y , Lee S , Vazquez S , Pallas M |
| Ref : CNS Neurosci Ther , : , 2023 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2023_CNS.Neurosci.Ther__ |
| PubMedID: 37905690 |
| Title : Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors - Codony_2022_J.Med.Chem_65_13660 |
| Author(s) : Codony S , Entrena JM , Calvo-Tusell C , Jora B , Gonzalez-Cano R , Osuna S , Corpas R , Morisseau C , Perez B , Barniol-Xicota M , Grinan-Ferre C , Perez C , Rodriguez-Franco MI , Martinez AL , Loza MI , Pallas M , Verhelst SHL , Sanfeliu C , Feixas F , Hammock BD , Brea J , Cobos EJ , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 65 :13660 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_13660 |
| PubMedID: 36222708 |
| Title : Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Codony_2022_J.Med.Chem_65_4909 |
| Author(s) : Codony S , Pont C , Grinan-Ferre C , Di Pede-Mattatelli A , Calvo-Tusell C , Feixas F , Osuna S , Jarne-Ferrer J , Naldi M , Bartolini M , Loza MI , Brea J , Perez B , Bartra C , Sanfeliu C , Juarez-Jimenez J , Morisseau C , Hammock BD , Pallas M , Vazquez S , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 65 :4909 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_4909 |
| PubMedID: 35271276 |
| Title : Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer's Disease Neurodegeneration - Bartra_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Bartra C , Irisarri A , Villoslada A , Corpas R , Aguirre S , Garcia-Lara E , Sunol C , Pallas M , Grinan-Ferre C , Sanfeliu C |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Bartra_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 36499477 |
| Title : A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer's Disease Mice Models - Jarne-Ferrer_2022_Pharmaceuticals.(Basel)_15_ |
| Author(s) : Jarne-Ferrer J , Grinan-Ferre C , Bellver-Sanchis A , Vazquez S , Munoz-Torrero D , Pallas M |
| Ref : Pharmaceuticals (Basel) , 15 : , 2022 |
| Abstract : |
| PubMedSearch : Jarne-Ferrer_2022_Pharmaceuticals.(Basel)_15_ |
| PubMedID: 35893732 |
| Title : From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects - Pont_2021_Eur.J.Med.Chem_225_113779 |
| Author(s) : Pont C , Ginex T , Grinan-Ferre C , Scheiner M , Mattellone A , Martinez N , Arce EM , Soriano-Fernandez Y , Naldi M , De Simone A , Barenys M , Gomez-Catalan J , Perez B , Sabate R , Andrisano V , Loza MI , Brea J , Bartolini M , Bolognesi ML , Decker M , Pallas M , Luque FJ , Munoz-Torrero D |
| Ref : Eur Journal of Medicinal Chemistry , 225 :113779 , 2021 |
| Abstract : |
| PubMedSearch : Pont_2021_Eur.J.Med.Chem_225_113779 |
| PubMedID: 34418785 |
| Title : From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis - Codony_2021_J.Med.Chem__ |
| Author(s) : Codony S , Calvo-Tusell C , Valverde E , Osuna S , Morisseau C , Loza MI , Brea J , Perez C , Rodriguez-Franco MI , Pizarro-Delgado J , Corpas R , Grinan-Ferre C , Pallas M , Sanfeliu C , Vazquez-Carrera M , Hammock BD , Feixas F , Vazquez S |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Codony_2021_J.Med.Chem__ |
| PubMedID: 33945278 |
| Title : Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: A Comparative study with donepezil - Vasilopoulou_2021_Br.J.Pharmacol__ |
| Author(s) : Vasilopoulou F , Rodriguez-Arevalo S , Bagan A , Escolano C , Grinan-Ferre C , Pallas M |
| Ref : British Journal of Pharmacology , : , 2021 |
| Abstract : |
| PubMedSearch : Vasilopoulou_2021_Br.J.Pharmacol__ |
| PubMedID: 33817786 |
| Title : Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease - Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Grinan-Ferre C , Companys-Alemany J , Jarne-Ferrer J , Codony S , Gonzalez-Castillo C , Ortuno-Sahagun D , Vilageliu L , Grinberg D , Vazquez S , Pallas M |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33810307 |
| Title : Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6 - Perez-Areales_2020_J.Med.Chem_63_9360 |
| Author(s) : Perez-Areales FJ , Garrido M , Aso E , Bartolini M , De Simone A , Espargaro A , Ginex T , Sabate R , Perez B , Andrisano V , Puigoriol-Illamola D , Pallas M , Luque FJ , Loza MI , Brea J , Ferrer I , Ciruela F , Messeguer A , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 63 :9360 , 2020 |
| Abstract : |
| PubMedSearch : Perez-Areales_2020_J.Med.Chem_63_9360 |
| PubMedID: 32706255 |
| Title : Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy - Pallas_2020_Biomolecules_10_ |
| Author(s) : Pallas M , Vazquez S , Sanfeliu C , Galdeano C , Grinan-Ferre C |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Pallas_2020_Biomolecules_10_ |
| PubMedID: 32369955 |
| Title : Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease - Grinan-Ferre_2020_Neurotherapeutics__ |
| Author(s) : Grinan-Ferre C , Codony S , Pujol E , Yang J , Leiva R , Escolano C , Puigoriol-Illamola D , Companys-Alemany J , Corpas R , Sanfeliu C , Perez B , Loza MI , Brea J , Morisseau C , Hammock BD , Vazquez S , Pallas M , Galdeano C |
| Ref : Neurotherapeutics , : , 2020 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2020_Neurotherapeutics__ |
| PubMedID: 32488482 |
| Title : Novel huprine derivatives with inhibitory activity toward beta-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates - Viayna_2010_ChemMedChem_5_1855 |
| Author(s) : Viayna E , Gomez T , Galdeano C , Ramirez L , Ratia M , Badia A , Clos MV , Verdaguer E , Junyent F , Camins A , Pallas M , Bartolini M , Mancini F , Andrisano V , Arce MP , Rodriguez-Franco MI , Bidon-Chanal A , Luque FJ , Camps P , Munoz-Torrero D |
| Ref : ChemMedChem , 5 :1855 , 2010 |
| Abstract : |
| PubMedSearch : Viayna_2010_ChemMedChem_5_1855 |
| PubMedID: 20859987 |
| Title : Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation - Camps_2008_J.Med.Chem_51_3588 |
| Author(s) : Camps P , Formosa X , Galdeano C , Gomez T , Munoz-Torrero D , Scarpellini M , Viayna E , Badia A , Clos MV , Camins A , Pallas M , Bartolini M , Mancini F , Andrisano V , Estelrich J , Lizondo M , Bidon-Chanal A , Luque FJ |
| Ref : Journal of Medicinal Chemistry , 51 :3588 , 2008 |
| Abstract : |
| PubMedSearch : Camps_2008_J.Med.Chem_51_3588 |
| PubMedID: 18517184 |
| Title : (+\/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration - Jorda_2004_J.Alzheimers.Dis_6_577 |
| Author(s) : Jorda EG , Verdaguer E , Jimenez A , Canudas AM , Rimbau V , Camps P , Munoz-Torrero D , Camins A , Pallas M |
| Ref : J Alzheimers Dis , 6 :577 , 2004 |
| Abstract : |
| PubMedSearch : Jorda_2004_J.Alzheimers.Dis_6_577 |
| PubMedID: 15665397 |