Full name : Drenan Ryan M
First name : Ryan M
Mail : Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN
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Country : USA
Email : drenan@purdue.edu
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Comment
Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS |
Ref : Sci Transl Med , 7 :287ra72 , 2015 |
Abstract : |
PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
PubMedID: 25972004 |
Title : Evidence for a role for alpha6( *) nAChRs in l-dopa-induced dyskinesias using Parkinsonian alpha6( *) nAChR gain-of-function mice - Bordia_2015_Neurosci_295_187 |
Author(s) : Bordia T , McGregor M , McIntosh JM , Drenan RM , Quik M |
Ref : Neuroscience , 295 :187 , 2015 |
Abstract : |
PubMedSearch : Bordia_2015_Neurosci_295_187 |
PubMedID: 25813704 |
Title : Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors - Henderson_2014_J.Gen.Physiol_143_51 |
Author(s) : Henderson BJ , Srinivasan R , Nichols WA , Dilworth CN , Gutierrez DF , Mackey ED , McKinney S , Drenan RM , Richards CI , Lester HA |
Ref : Journal of General Physiology , 143 :51 , 2014 |
Abstract : |
PubMedSearch : Henderson_2014_J.Gen.Physiol_143_51 |
PubMedID: 24378908 |
Title : Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior - Cohen_2012_Neurosci_200_31 |
Author(s) : Cohen BN , Mackey ED , Grady SR , McKinney S , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA , Drenan RM |
Ref : Neuroscience , 200 :31 , 2012 |
Abstract : |
PubMedSearch : Cohen_2012_Neurosci_200_31 |
PubMedID: 22079576 |
Title : Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations - Drenan_2012_Pharmacol.Rev_64_869 |
Author(s) : Drenan RM , Lester HA |
Ref : Pharmacol Rev , 64 :869 , 2012 |
Abstract : |
PubMedSearch : Drenan_2012_Pharmacol.Rev_64_869 |
PubMedID: 22885704 |
Title : alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit - Mackey_2012_J.Neurosci_32_10226 |
Author(s) : Mackey ED , Engle SE , Kim MR , O'Neill HC , Wageman CR , Patzlaff NE , Wang Y , Grady SR , McIntosh JM , Marks MJ , Lester HA , Drenan RM |
Ref : Journal of Neuroscience , 32 :10226 , 2012 |
Abstract : |
PubMedSearch : Mackey_2012_J.Neurosci_32_10226 |
PubMedID: 22836257 |
Title : Characterizing functional alpha6beta2 nicotinic acetylcholine receptors in vitro: mutant beta2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells - Xiao_2011_Biochem.Pharmacol_82(8)_852 |
Author(s) : Xiao C , Srinivasan R , Drenan RM , Mackey ED , McIntosh JM , Lester HA |
Ref : Biochemical Pharmacology , 82 :852 , 2011 |
Abstract : |
PubMedSearch : Xiao_2011_Biochem.Pharmacol_82(8)_852 |
PubMedID: 21609715 |
Title : Poster: alpha6* nAChR expression and function in brain areas influencing DA transmission probed with alpha6-GFP transgenic mice - |
Author(s) : Drenan RM , Mackey EDW , Grady SR , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA |
Ref : Biochemical Pharmacology , 82 :1035 , 2011 |
PubMedID: |
Title : Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors - Grady_2010_Neuropharmacol_58_1054 |
Author(s) : Grady SR , Drenan RM , Breining SR , Yohannes D , Wageman CR , Fedorov NB , McKinney S , Whiteaker P , Bencherif M , Lester HA , Marks MJ |
Ref : Neuropharmacology , 58 :1054 , 2010 |
Abstract : |
PubMedSearch : Grady_2010_Neuropharmacol_58_1054 |
PubMedID: 20114055 |
Title : Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors - Drenan_2010_J.Neurosci_30_9877 |
Author(s) : Drenan RM , Grady SR , Steele AD , McKinney S , Patzlaff NE , McIntosh JM , Marks MJ , Miwa JM , Lester HA |
Ref : Journal of Neuroscience , 30 :9877 , 2010 |
Abstract : |
PubMedSearch : Drenan_2010_J.Neurosci_30_9877 |
PubMedID: 20660270 |
Title : In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors - Drenan_2008_Neuron_60_123 |
Author(s) : Drenan RM , Grady SR , Whiteaker P , McClure-Begley TD , McKinney S , Miwa JM , Bupp S , Heintz N , McIntosh JM , Bencherif M , Marks MJ , Lester HA |
Ref : Neuron , 60 :123 , 2008 |
Abstract : |
PubMedSearch : Drenan_2008_Neuron_60_123 |
PubMedID: 18940593 |
Title : Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits - Drenan_2008_Mol.Pharmacol_73_27 |
Author(s) : Drenan RM , Nashmi R , Imoukhuede P , Just H , McKinney S , Lester HA |
Ref : Molecular Pharmacology , 73 :27 , 2008 |
Abstract : |
PubMedSearch : Drenan_2008_Mol.Pharmacol_73_27 |
PubMedID: 17932221 |