| Title : In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time - Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| Author(s) : Verhulst E , Brzeminski P , de Groot A , Wals JW , Michiels R , Fabisiak A , Thys J , Grintsevich S , Van Rymenant Y , Peeters S , Lambregts S , Sim Y , Verstraete R , Van Wielendaele P , Berg M , Elvas F , Van Ostade X , Rosch F , Lambeir AM , De Winter H , Van der Veken P , De Meester I |
| Ref : Eur Journal of Medicinal Chemistry , 304 :118494 , 2026 |
| Abstract : |
| PubMedSearch : Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| PubMedID: 41455278 |
| Gene_locus related to this paper: human-FAP |
| Title : Structure-Property Investigation of New KetoFAPI Inhibitors of Fibroblast Activation Protein (FAP): Discovery of Highly Potent, Selective Compounds with Prolonged Residence Times and Promising Radiotheranostic Potential - Brzeminski_2025_J.Med.Chem_68_21739 |
| Author(s) : Brzeminski P , Verhulst E , Fabisiak A , Pacifico R , Willocx D , Peeters S , de Groot A , Corthaut S , Van Meel K , Stroobants S , Augustyns K , Berg M , Lambeir AM , Rosch F , De Meester I , Elvas F , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 68 :21739 , 2025 |
| Abstract : |
| PubMedSearch : Brzeminski_2025_J.Med.Chem_68_21739 |
| PubMedID: 41086263 |
| Gene_locus related to this paper: human-FAP |
| Title : Synthesis and Preclinical Evaluation of Druglike (18)F-Labeled Fibroblast Activation Protein (FAP) Inhibitors with Enhanced Tumor Retention - Adhikari_2025_Bioconjug.Chem_36_1887 |
| Author(s) : Adhikari K , Grintsevich S , de Groot A , Verhulst E , Van Rymenant Y , Vangestel C , Lauwerys L , Miranda A , De Meester I , Van der Veken P , Elvas F |
| Ref : Bioconjug Chem , 36 :1887 , 2025 |
| Abstract : |
| PubMedSearch : Adhikari_2025_Bioconjug.Chem_36_1887 |
| PubMedID: 40790340 |
| Title : Next generation fibroblast activation protein (FAP) targeting PET tracers - The tetrazine ligation allows an easy and convenient way to (18)F-labeled (4-quinolinoyl)glycyl-2-cyanopyrrolidines - Poulie_2023_Eur.J.Med.Chem_262_115862 |
| Author(s) : Poulie CBM , Shalgunov V , Elvas F , Van Rymenant Y , Moon ES , Battisti UM , De Loose J , De Meester I , Rosch F , Van der Veken P , Herth MM |
| Ref : Eur Journal of Medicinal Chemistry , 262 :115862 , 2023 |
| Abstract : |
| PubMedSearch : Poulie_2023_Eur.J.Med.Chem_262_115862 |
| PubMedID: 37883899 |
| Title : Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA(5m) chelators - Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| Author(s) : Moon ES , Elvas F , Vliegen G , De Lombaerde S , Vangestel C , De Bruycker S , Bracke A , Eppard E , Greifenstein L , Klasen B , Kramer V , Staelens S , De Meester I , Van der Veken P , Rosch F |
| Ref : EJNMMI Radiopharm Chem , 5 :19 , 2020 |
| Abstract : |
| PubMedSearch : Moon_2020_EJNMMI.Radiopharm.Chem_5_19 |
| PubMedID: 32728930 |