| Title : Highly potent dipeptidyl peptidase 8\/9 (DPP8\/9) inhibitors designed via relative binding free energy calculations - Nozal_2025_Eur.J.Med.Chem_297_117913 |
| Author(s) : Nozal V , Beyens O , Peeters S , Fabisiak A , Augustyns K , De Meester I , Van der Veken P , De Winter H |
| Ref : Eur Journal of Medicinal Chemistry , 297 :117913 , 2025 |
| Abstract : |
| PubMedSearch : Nozal_2025_Eur.J.Med.Chem_297_117913 |
| PubMedID: 40609224 |
| Title : Cosolvent Molecular Dynamics Applied to DPP4, DPP8 and DPP9: Reproduction of Important Binding Features and Use in Inhibitor Design - Beyens_2024_J.Chem.Inf.Model_64_7650 |
| Author(s) : Beyens O , Corthaut S , Peeters S , Van der Veken P , De Meester I , De Winter H |
| Ref : J Chem Inf Model , 64 :7650 , 2024 |
| Abstract : |
| PubMedSearch : Beyens_2024_J.Chem.Inf.Model_64_7650 |
| PubMedID: 39332821 |
| Title : An interdisciplinary approach provides insights into the pronounced selectivity of compound 42 for DPP9 - Beyens_2024_ChemMedChem__e202400700 |
| Author(s) : Beyens O , Corthaut S , Lambeir AM , Van der Veken P , Sterckx YG , De Meester I , De Winter H |
| Ref : ChemMedChem , :e202400700 , 2024 |
| Abstract : |
| PubMedSearch : Beyens_2024_ChemMedChem__e202400700 |
| PubMedID: 39552560 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin - Benramdane_2023_J.Med.Chem__ |
| Author(s) : Benramdane S , De Loose J , Filippi N , Espadinha M , Beyens O , Rymenant YV , Dirkx L , Bozdag M , Feijens PB , Augustyns K , Caljon G , De Winter H , De Meester I , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Benramdane_2023_J.Med.Chem__ |
| PubMedID: 37721854 |
| Title : Vildagliptin-Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8\/9-Specific Lead - Benramdane_2022_ChemMedChem__e202200097 |
| Author(s) : Benramdane S , De Loose J , Beyens O , Van Rymenant Y , Vliegen G , Augustyns K , De Winter H , De Meester I , Van der Veken P |
| Ref : ChemMedChem , :e202200097 , 2022 |
| Abstract : |
| PubMedSearch : Benramdane_2022_ChemMedChem__e202200097 |
| PubMedID: 35760756 |
| Title : Spectrophores as one-dimensional descriptors calculated from three-dimensional atomic properties: applications ranging from scaffold hopping to multi-target virtual screening - Gladysz_2018_J.Cheminform_10_9 |
| Author(s) : Gladysz R , Dos Santos FM , Langenaeker W , Thijs G , Augustyns K , De Winter H |
| Ref : J Cheminform , 10 :9 , 2018 |
| Abstract : |
| PubMedSearch : Gladysz_2018_J.Cheminform_10_9 |
| PubMedID: 29516311 |
| Title : Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling - Rea_2017_Eur.J.Med.Chem_139_482 |
| Author(s) : Rea D , Van Elzen R , De Winter H , Van Goethem S , Landuyt B , Luyten W , Schoofs L , Van der Veken P , Augustyns K , De Meester I , Fulop V , Lambeir AM |
| Ref : Eur Journal of Medicinal Chemistry , 139 :482 , 2017 |
| Abstract : |
| PubMedSearch : Rea_2017_Eur.J.Med.Chem_139_482 |
| PubMedID: 28826083 |
| Gene_locus related to this paper: porgi-DPP |