| Title : In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time - Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| Author(s) : Verhulst E , Brzeminski P , de Groot A , Wals JW , Michiels R , Fabisiak A , Thys J , Grintsevich S , Van Rymenant Y , Peeters S , Lambregts S , Sim Y , Verstraete R , Van Wielendaele P , Berg M , Elvas F , Van Ostade X , Rosch F , Lambeir AM , De Winter H , Van der Veken P , De Meester I |
| Ref : Eur Journal of Medicinal Chemistry , 304 :118494 , 2026 |
| Abstract : |
| PubMedSearch : Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| PubMedID: 41455278 |
| Gene_locus related to this paper: human-FAP |
| Title : Structure-Property Investigation of New KetoFAPI Inhibitors of Fibroblast Activation Protein (FAP): Discovery of Highly Potent, Selective Compounds with Prolonged Residence Times and Promising Radiotheranostic Potential - Brzeminski_2025_J.Med.Chem_68_21739 |
| Author(s) : Brzeminski P , Verhulst E , Fabisiak A , Pacifico R , Willocx D , Peeters S , de Groot A , Corthaut S , Van Meel K , Stroobants S , Augustyns K , Berg M , Lambeir AM , Rosch F , De Meester I , Elvas F , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 68 :21739 , 2025 |
| Abstract : |
| PubMedSearch : Brzeminski_2025_J.Med.Chem_68_21739 |
| PubMedID: 41086263 |
| Gene_locus related to this paper: human-FAP |
| Title : Highly potent dipeptidyl peptidase 8\/9 (DPP8\/9) inhibitors designed via relative binding free energy calculations - Nozal_2025_Eur.J.Med.Chem_297_117913 |
| Author(s) : Nozal V , Beyens O , Peeters S , Fabisiak A , Augustyns K , De Meester I , Van der Veken P , De Winter H |
| Ref : Eur Journal of Medicinal Chemistry , 297 :117913 , 2025 |
| Abstract : |
| PubMedSearch : Nozal_2025_Eur.J.Med.Chem_297_117913 |
| PubMedID: 40609224 |
| Title : Selective and Orally Bioavailable Dipeptidyl Peptidase 9 Inhibitors with Potent Pyroptosis Induction Properties - Filippi_2025_J.Med.Chem__ |
| Author(s) : Filippi N , Mertens K , De Loose J , Benramdane S , Hermans R , Espadinha M , Dirkx L , Feijens PB , Nozal V , Verhulst E , Peeters S , Gomard T , Corthaut S , Augustyns K , Caljon G , Schols D , De Meester I , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Filippi_2025_J.Med.Chem__ |
| PubMedID: 41160575 |
| Gene_locus related to this paper: human-DPP9 |
| Title : Cosolvent Molecular Dynamics Applied to DPP4, DPP8 and DPP9: Reproduction of Important Binding Features and Use in Inhibitor Design - Beyens_2024_J.Chem.Inf.Model_64_7650 |
| Author(s) : Beyens O , Corthaut S , Peeters S , Van der Veken P , De Meester I , De Winter H |
| Ref : J Chem Inf Model , 64 :7650 , 2024 |
| Abstract : |
| PubMedSearch : Beyens_2024_J.Chem.Inf.Model_64_7650 |
| PubMedID: 39332821 |