| Title : In vitro kinetic profiling by enzymatic approaches to select FAPIs with a long residence time - Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| Author(s) : Verhulst E , Brzeminski P , de Groot A , Wals JW , Michiels R , Fabisiak A , Thys J , Grintsevich S , Van Rymenant Y , Peeters S , Lambregts S , Sim Y , Verstraete R , Van Wielendaele P , Berg M , Elvas F , Van Ostade X , Rosch F , Lambeir AM , De Winter H , Van der Veken P , De Meester I |
| Ref : Eur Journal of Medicinal Chemistry , 304 :118494 , 2026 |
| Abstract : |
| PubMedSearch : Verhulst_2026_Eur.J.Med.Chem_304_118494 |
| PubMedID: 41455278 |
| Gene_locus related to this paper: human-FAP |
| Title : Preclinical evaluation of homodimeric FAPI target modules for UniCAR-mediated targeting of FAP-expressing tumor and stromal cells - Boutier_2026_Oncoimmunology_15_2717836 |
| Author(s) : Boutier H , Mattiussi S , Loureiro LR , Berndt N , Stammberger A , Jones-Cifuentes N , Hoffmann L , Verhulst E , Schmitz M , De Meester I , Battisti UM , Arndt C , Feldmann A , Roesch F , Herth MM , Bachmann M |
| Ref : Oncoimmunology , 15 :2717836 , 2026 |
| Abstract : |
| PubMedSearch : Boutier_2026_Oncoimmunology_15_2717836 |
| PubMedID: 42627862 |
| Title : Structure-Property Investigation of New KetoFAPI Inhibitors of Fibroblast Activation Protein (FAP): Discovery of Highly Potent, Selective Compounds with Prolonged Residence Times and Promising Radiotheranostic Potential - Brzeminski_2025_J.Med.Chem_68_21739 |
| Author(s) : Brzeminski P , Verhulst E , Fabisiak A , Pacifico R , Willocx D , Peeters S , de Groot A , Corthaut S , Van Meel K , Stroobants S , Augustyns K , Berg M , Lambeir AM , Rosch F , De Meester I , Elvas F , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 68 :21739 , 2025 |
| Abstract : |
| PubMedSearch : Brzeminski_2025_J.Med.Chem_68_21739 |
| PubMedID: 41086263 |
| Gene_locus related to this paper: human-FAP |
| Title : Fibroblast activation protein on human natural killer cells: insights from natural killer cell activation and crosstalk with cancer-associated fibroblasts - Van Rymenant_2025_J.Leukoc.Biol_117_ |
| Author(s) : Van Rymenant Y , de Groot A , Dirkx L , Verhulst E , De Loose J , Pintelon I , Verhezen T , De Waele J , Thys S , De Wever O , Tanc M , Caljon G , Van der Veken P , De Meester I |
| Ref : J Leukoc Biol , 117 : , 2025 |
| Abstract : |
| PubMedSearch : Van Rymenant_2025_J.Leukoc.Biol_117_ |
| PubMedID: 40638797 |
| Gene_locus related to this paper: human-FAP |
| Title : Synthesis and Preclinical Evaluation of Druglike (18)F-Labeled Fibroblast Activation Protein (FAP) Inhibitors with Enhanced Tumor Retention - Adhikari_2025_Bioconjug.Chem_36_1887 |
| Author(s) : Adhikari K , Grintsevich S , de Groot A , Verhulst E , Van Rymenant Y , Vangestel C , Lauwerys L , Miranda A , De Meester I , Van der Veken P , Elvas F |
| Ref : Bioconjug Chem , 36 :1887 , 2025 |
| Abstract : |
| PubMedSearch : Adhikari_2025_Bioconjug.Chem_36_1887 |
| PubMedID: 40790340 |
| Title : Selective and Orally Bioavailable Dipeptidyl Peptidase 9 Inhibitors with Potent Pyroptosis Induction Properties - Filippi_2025_J.Med.Chem__ |
| Author(s) : Filippi N , Mertens K , De Loose J , Benramdane S , Hermans R , Espadinha M , Dirkx L , Feijens PB , Nozal V , Verhulst E , Peeters S , Gomard T , Corthaut S , Augustyns K , Caljon G , Schols D , De Meester I , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , : , 2025 |
| Abstract : |
| PubMedSearch : Filippi_2025_J.Med.Chem__ |
| PubMedID: 41160575 |
| Gene_locus related to this paper: human-DPP9 |
| Title : Active site-directed probes targeting dipeptidyl peptidases 8 and 9 - Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| Author(s) : Espadinha M , De Loose J , Corthaut S , Thys S , Van Rymenant Y , Verhulst E , Benramdane S , Filippi N , Augustyns K , Van Wielendaele P , Pintelon I , De Meester I , Van der Veken P |
| Ref : Eur Journal of Medicinal Chemistry , 270 :116389 , 2024 |
| Abstract : |
| PubMedSearch : Espadinha_2024_Eur.J.Med.Chem_270_116389 |
| PubMedID: 38593588 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : Novel Generation of FAP Inhibitor-Based Homodimers for Improved Application in Radiotheranostics - Martin_2023_Cancers.(Basel)_15_ |
| Author(s) : Martin M , Ballal S , Yadav MP , Bal C , Van Rymenant Y , De Loose J , Verhulst E , De Meester I , Van der Veken P , Roesch F |
| Ref : Cancers (Basel) , 15 : , 2023 |
| Abstract : |
| PubMedSearch : Martin_2023_Cancers.(Basel)_15_ |
| PubMedID: 36980775 |