Title : SAR of alpha7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore - Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
Author(s) : Schrimpf MR , Sippy KB , Briggs CA , Anderson DJ , Li T , Ji J , Frost JM , Surowy CS , Bunnelle WH , Gopalakrishnan M , Meyer MD |
Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1633 , 2012 |
Abstract : |
PubMedSearch : Schrimpf_2012_Bioorg.Med.Chem.Lett_22_1633 |
PubMedID: 22281189 |
Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65 |
Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH |
Ref : CNS Neurosci Ther , 14 :65 , 2008 |
Abstract : |
PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65 |
PubMedID: 18482100 |
Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578 |
Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M |
Ref : Journal of Neuroscience , 27 :10578 , 2007 |
Abstract : |
PubMedSearch : Bitner_2007_J.Neurosci_27_10578 |
PubMedID: 17898229 |