Timmermann DB

General

Full name : Timmermann Daniel B

First name : Daniel B

Mail : Aniona ApS, Baltorpvej 154, DK-2750 Ballerup

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Country : Denmark

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References (18)

Title : Biophysical and pharmacological characterization of alpha6-containing nicotinic acetylcholine receptors expressed in HEK293 cells - Rasmussen_2014_Brain.Res_1542_1
Author(s) : Rasmussen AH , Strobaek D , Dyhring T , Jensen ML , Peters D , Grunnet M , Timmermann DB , Ahring PK
Ref : Brain Research , 1542 :1 , 2014
Abstract :
PubMedSearch : Rasmussen_2014_Brain.Res_1542_1
PubMedID: 24157862

Title : Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors - Harpsoe_2013_J.Biol.Chem_288_2559
Author(s) : Harpsoe K , Hald H , Timmermann DB , Jensen ML , Dyhring T , Nielsen EO , Peters D , Balle T , Gajhede M , Kastrup JS , Ahring PK
Ref : Journal of Biological Chemistry , 288 :2559 , 2013
Abstract :
PubMedSearch : Harpsoe_2013_J.Biol.Chem_288_2559
PubMedID: 23229547

Title : Positive allosteric modulation of alpha4beta2 nAChR agonist induced behaviour - Rode_2012_Brain.Res_1458_67
Author(s) : Rode F , Munro G , Holst D , Nielsen EO , Troelsen KB , Timmermann DB , Ronn LC , Grunnet M
Ref : Brain Research , 1458 :67 , 2012
Abstract :
PubMedSearch : Rode_2012_Brain.Res_1458_67
PubMedID: 22552114

Title : Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of alpha2- and alpha4-containing nicotinic acetylcholine receptors - Timmermann_2012_Br.J.Pharmacol_167_164
Author(s) : Timmermann DB , Sandager-Nielsen K , Dyhring T , Smith M , Jacobsen AM , Nielsen EO , Grunnet M , Christensen JK , Peters D , Kohlhaas KL , Olsen GM , Ahring PK
Ref : British Journal of Pharmacology , 167 :164 , 2012
Abstract :
PubMedSearch : Timmermann_2012_Br.J.Pharmacol_167_164
PubMedID: 22506660

Title : Poster: Differential allosteric modulation of high- and low-sensitivity forms of the alpha4\/beta2 nAChR: Evidence for distinct modulator binding sites -
Author(s) : Timmermann DB , Grunnet M , Peters D , Ahring PK
Ref : Biochemical Pharmacology , 82 :1031 , 2011
PubMedID:

Title : 11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements - Ettrup_2011_J.Nucl.Med_52_1449
Author(s) : Ettrup A , Mikkelsen JD , Lehel S , Madsen J , Nielsen EO , Palner M , Timmermann DB , Peters D , Knudsen GM
Ref : J Nucl Med , 52 :1449 , 2011
Abstract :
PubMedSearch : Ettrup_2011_J.Nucl.Med_52_1449
PubMedID: 21828113

Title : In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107 - Malysz_2010_J.Pharmacol.Exp.Ther_334_863
Author(s) : Malysz J , Anderson DJ , Gronlien JH , Ji J , Bunnelle WH , Hakerud M , Thorin-Hagene K , Ween H , Helfrich R , Hu M , Gubbins E , Gopalakrishnan S , Puttfarcken PS , Briggs CA , Li J , Meyer MD , Dyhring T , Ahring PK , Nielsen EO , Peters D , Timmermann DB , Gopalakrishnan M
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :863 , 2010
Abstract :
PubMedSearch : Malysz_2010_J.Pharmacol.Exp.Ther_334_863
PubMedID: 20504915

Title : Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice - Redrobe_2009_Eur.J.Pharmacol_602_58
Author(s) : Redrobe JP , Nielsen EO , Christensen JK , Peters D , Timmermann DB , Olsen GM
Ref : European Journal of Pharmacology , 602 :58 , 2009
Abstract :
PubMedSearch : Redrobe_2009_Eur.J.Pharmacol_602_58
PubMedID: 18848931

Title : Poster: In vitro pharmacological profile of a novel alpha4\/beta2 positive allosteric modulator NS9283 (A-969933) -
Author(s) : Malysz J , Dyhring T , Ahring PK , Olsen GM , Peters D , Gronlien JH , Wetterstrand C , Ween H , Haakerud M , Thorin-Hagene K , Andersen E , Anderson DJ , Hu M , Kroeger PE , Lee CHL , Gopalakrishnan M , Timmermann DB
Ref : Biochemical Pharmacology , 78 :919 , 2009
PubMedID:

Title : Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors - Briggs_2009_Br.J.Pharmacol_158_1486
Author(s) : Briggs CA , Gronlien JH , Curzon P , Timmermann DB , Ween H , Thorin-Hagene K , Kerr P , Anderson DJ , Malysz J , Dyhring T , Olsen GM , Peters D , Bunnelle WH , Gopalakrishnan M
Ref : British Journal of Pharmacology , 158 :1486 , 2009
Abstract :
PubMedSearch : Briggs_2009_Br.J.Pharmacol_158_1486
PubMedID: 19845675

Title : Evaluation of alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators using the parallel oocyte electrophysiology test station - Malysz_2009_Assay.Drug.Dev.Technol_7_374
Author(s) : Malysz J , Gronlien JH , Timmermann DB , Hakerud M , Thorin-Hagene K , Ween H , Trumbull JD , Xiong Y , Briggs CA , Ahring PK , Dyhring T , Gopalakrishnan M
Ref : Assay Drug Dev Technol , 7 :374 , 2009
Abstract :
PubMedSearch : Malysz_2009_Assay.Drug.Dev.Technol_7_374
PubMedID: 19689206

Title : Molecular imaging of alpha7 nicotinic acetylcholine receptors: design and evaluation of the potent radioligand [18F]NS10743 - Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791
Author(s) : Deuther-Conrad W , Fischer S , Hiller A , Nielsen EO , Timmermann DB , Steinbach J , Sabri O , Peters D , Brust P
Ref : Eur J Nucl Med Mol Imaging , 36 :791 , 2009
Abstract :
PubMedSearch : Deuther-Conrad_2009_Eur.J.Nucl.Med.Mol.Imaging_36_791
PubMedID: 19137292

Title : The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat - Thomsen_2008_Neurosci_154_741
Author(s) : Thomsen MS , Mikkelsen JD , Timmermann DB , Peters D , Hay-Schmidt A , Martens H , Hansen HH
Ref : Neuroscience , 154 :741 , 2008
Abstract :
PubMedSearch : Thomsen_2008_Neurosci_154_741
PubMedID: 18495359

Title : An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo - Timmermann_2007_J.Pharmacol.Exp.Ther_323_294
Author(s) : Timmermann DB , Gronlien JH , Kohlhaas KL , Nielsen EO , Dam E , Jorgensen TD , Ahring PK , Peters D , Holst D , Christensen JK , Malysz J , Briggs CA , Gopalakrishnan M , Olsen GM
Ref : Journal of Pharmacology & Experimental Therapeutics , 323 :294 , 2007
Abstract :
PubMedSearch : Timmermann_2007_J.Pharmacol.Exp.Ther_323_294
PubMedID: 17625074

Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578
Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M
Ref : Journal of Neuroscience , 27 :10578 , 2007
Abstract :
PubMedSearch : Bitner_2007_J.Neurosci_27_10578
PubMedID: 17898229

Title : Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: an effect similar to antipsychotics - Hansen_2007_J.Neurosci.Res_85_1810
Author(s) : Hansen HH , Timmermann DB , Peters D , Walters C , Damaj MI , Mikkelsen JD
Ref : Journal of Neuroscience Research , 85 :1810 , 2007
Abstract :
PubMedSearch : Hansen_2007_J.Neurosci.Res_85_1810
PubMedID: 17455307

Title : The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat - Kristensen_2007_Neurosci.Lett_418_154
Author(s) : Kristensen SE , Thomsen MS , Hansen HH , Timmermann DB , Hay-Schmidt A , Mikkelsen JD
Ref : Neuroscience Letters , 418 :154 , 2007
Abstract :
PubMedSearch : Kristensen_2007_Neurosci.Lett_418_154
PubMedID: 17379406

Title : The beta subunit determines the ion selectivity of the GABAA receptor - Jensen_2002_J.Biol.Chem_277_41438
Author(s) : Jensen ML , Timmermann DB , Johansen TH , Schousboe A , Varming T , Ahring PK
Ref : Journal of Biological Chemistry , 277 :41438 , 2002
Abstract :
PubMedSearch : Jensen_2002_J.Biol.Chem_277_41438
PubMedID: 12177063