Thorin-Hagene K

References (12)

Title : Poster: In vitro pharmacological characterization of ABT-779, a novel positive allosteric modulator of alpha7 nAChRs -
Author(s) : Malysz J , Gronlien JH , Briggs CA , Anderson DJ , El-Kouhen R , Drescher K , Ween H , Thorin-Hagene K , Mortell K , Lee C-H , Gopalakrishnan M
Ref : Biochemical Pharmacology , 82 :1030 , 2011
PubMedID:

Title : Importance of M2-M3 loop in governing properties of genistein at the alpha7 nicotinic acetylcholine receptor inferred from alpha7\/5-HT3A chimera - Gronlien_2010_Eur.J.Pharmacol_647_37
Author(s) : Gronlien JH , Ween H , Thorin-Hagene K , Cassar S , Li J , Briggs CA , Gopalakrishnan M , Malysz J
Ref : European Journal of Pharmacology , 647 :37 , 2010
Abstract :
PubMedSearch : Gronlien_2010_Eur.J.Pharmacol_647_37
PubMedID: 20816816

Title : In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107 - Malysz_2010_J.Pharmacol.Exp.Ther_334_863
Author(s) : Malysz J , Anderson DJ , Gronlien JH , Ji J , Bunnelle WH , Hakerud M , Thorin-Hagene K , Ween H , Helfrich R , Hu M , Gubbins E , Gopalakrishnan S , Puttfarcken PS , Briggs CA , Li J , Meyer MD , Dyhring T , Ahring PK , Nielsen EO , Peters D , Timmermann DB , Gopalakrishnan M
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :863 , 2010
Abstract :
PubMedSearch : Malysz_2010_J.Pharmacol.Exp.Ther_334_863
PubMedID: 20504915

Title : Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells - Ween_2010_Neurochem.Int_57_269
Author(s) : Ween H , Thorin-Hagene K , Andersen E , Gronlien JH , Lee CH , Gopalakrishnan M , Malysz J
Ref : Neurochem Int , 57 :269 , 2010
Abstract :
PubMedSearch : Ween_2010_Neurochem.Int_57_269
PubMedID: 20558224

Title : Poster: In vitro pharmacological profile of a novel alpha4\/beta2 positive allosteric modulator NS9283 (A-969933) -
Author(s) : Malysz J , Dyhring T , Ahring PK , Olsen GM , Peters D , Gronlien JH , Wetterstrand C , Ween H , Haakerud M , Thorin-Hagene K , Andersen E , Anderson DJ , Hu M , Kroeger PE , Lee CHL , Gopalakrishnan M , Timmermann DB
Ref : Biochemical Pharmacology , 78 :919 , 2009
PubMedID:

Title : Poster: alpha3* and alpha7* nAChR mediated Ca2+ transient generation in neuroblastoma IMR-32 cells -
Author(s) : Ween H , Thorin-Hagene K , Andersen E , Gronlien JH , Lee L , Gopalakrishnan M , Malysz J
Ref : Biochemical Pharmacology , 78 :904 , 2009
PubMedID:

Title : Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors - Briggs_2009_Br.J.Pharmacol_158_1486
Author(s) : Briggs CA , Gronlien JH , Curzon P , Timmermann DB , Ween H , Thorin-Hagene K , Kerr P , Anderson DJ , Malysz J , Dyhring T , Olsen GM , Peters D , Bunnelle WH , Gopalakrishnan M
Ref : British Journal of Pharmacology , 158 :1486 , 2009
Abstract :
PubMedSearch : Briggs_2009_Br.J.Pharmacol_158_1486
PubMedID: 19845675

Title : In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile - Malysz_2009_J.Pharmacol.Exp.Ther_330_257
Author(s) : Malysz J , Gronlien JH , Anderson DJ , Hakerud M , Thorin-Hagene K , Ween H , Wetterstrand C , Briggs CA , Faghih R , Bunnelle WH , Gopalakrishnan M
Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :257 , 2009
Abstract :
PubMedSearch : Malysz_2009_J.Pharmacol.Exp.Ther_330_257
PubMedID: 19389923

Title : Evaluation of alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators using the parallel oocyte electrophysiology test station - Malysz_2009_Assay.Drug.Dev.Technol_7_374
Author(s) : Malysz J , Gronlien JH , Timmermann DB , Hakerud M , Thorin-Hagene K , Ween H , Trumbull JD , Xiong Y , Briggs CA , Ahring PK , Dyhring T , Gopalakrishnan M
Ref : Assay Drug Dev Technol , 7 :374 , 2009
Abstract :
PubMedSearch : Malysz_2009_Assay.Drug.Dev.Technol_7_374
PubMedID: 19689206

Title : alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues - Briggs_2008_Br.J.Pharmacol_153_1054
Author(s) : Briggs CA , Schrimpf MR , Anderson DJ , Gubbins EJ , Gronlien JH , Hakerud M , Ween H , Thorin-Hagene K , Malysz J , Li J , Bunnelle WH , Gopalakrishnan M , Meyer MD
Ref : British Journal of Pharmacology , 153 :1054 , 2008
Abstract :
PubMedSearch : Briggs_2008_Br.J.Pharmacol_153_1054
PubMedID: 18157163

Title : Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties - Tietje_2008_CNS.Neurosci.Ther_14_65
Author(s) : Tietje KR , Anderson DJ , Bitner RS , Blomme EA , Brackemeyer PJ , Briggs CA , Browman KE , Bury D , Curzon P , Drescher KU , Frost JM , Fryer RM , Fox GB , Gronlien JH , Hakerud M , Gubbins EJ , Halm S , Harris R , Helfrich RJ , Kohlhaas KL , Law D , Malysz J , Marsh KC , Martin RL , Meyer MD , Molesky AL , Nikkel AL , Otte S , Pan L , Puttfarcken PS , Radek RJ , Robb HM , Spies E , Thorin-Hagene K , Waring JF , Ween H , Xu H , Gopalakrishnan M , Bunnelle WH
Ref : CNS Neurosci Ther , 14 :65 , 2008
Abstract :
PubMedSearch : Tietje_2008_CNS.Neurosci.Ther_14_65
PubMedID: 18482100

Title : Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes - Gronlien_2007_Mol.Pharmacol_72_715
Author(s) : Gronlien JH , Hakerud M , Ween H , Thorin-Hagene K , Briggs CA , Gopalakrishnan M , Malysz J
Ref : Molecular Pharmacology , 72 :715 , 2007
Abstract :
PubMedSearch : Gronlien_2007_Mol.Pharmacol_72_715
PubMedID: 17565004