Decker MW

General

Full name : Decker Michael W

First name : Michael W

Mail : AbbVie, Incorporated, North Chicago, Illinois, USA

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Country : USA

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References (39)

Title : The alpha7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions - Bordia_2015_Exp.Neurol_263_277
Author(s) : Bordia T , McGregor M , Papke RL , Decker MW , McIntosh JM , Quik M
Ref : Experimental Neurology , 263 :277 , 2015
Abstract :
PubMedSearch : Bordia_2015_Exp.Neurol_263_277
PubMedID: 25261754

Title : Poster: Antidyskinetic effect of the novel alpha7 nicotinic receptor agonist ABT-126 in parkinsonian monkeys -
Author(s) : McGregor M , Danhui Zhang D , Tanuja Bordia T , Perez XA , Decker MW , Quik M
Ref : Biochemical Pharmacology , 97 :629 , 2015
PubMedID:

Title : The alpha7 nicotinic receptor agonist ABT-107 decreases L-Dopa-induced dyskinesias in parkinsonian monkeys - Zhang_2014_J.Pharmacol.Exp.Ther_351_25
Author(s) : Zhang D , McGregor M , Decker MW , Quik M
Ref : Journal of Pharmacology & Experimental Therapeutics , 351 :25 , 2014
Abstract :
PubMedSearch : Zhang_2014_J.Pharmacol.Exp.Ther_351_25
PubMedID: 25034405

Title : alpha7 Nicotinic Receptor Agonist Enhances Cognition in Aged 3xTg-AD Mice with Robust Plaques and Tangles - Medeiros_2014_Am.J.Pathol_184_520
Author(s) : Medeiros R , Castello NA , Cheng D , Kitazawa M , Baglietto-Vargas D , Green KN , Esbenshade TA , Bitner RS , Decker MW , LaFerla FM
Ref : American Journal of Pathology , 184 :520 , 2014
Abstract :
PubMedSearch : Medeiros_2014_Am.J.Pathol_184_520
PubMedID: 24269557

Title : ABT-089 and ABT-894 reduce levodopa-induced dyskinesias in a monkey model of Parkinson's disease - Zhang_2014_Mov.Disord_29_508
Author(s) : Zhang D , Bordia T , McGregor M , McIntosh JM , Decker MW , Quik M
Ref : Movement Disorders , 29 :508 , 2014
Abstract :
PubMedSearch : Zhang_2014_Mov.Disord_29_508
PubMedID: 24515328

Title : Neurobiology of nAChRs and cognition: a mini review of Dr. Jerry J. Buccafusco's contributions over a 25 year career - Terry_2011_Biochem.Pharmacol_82(8)_883
Author(s) : Terry AV, Jr. , Decker MW
Ref : Biochemical Pharmacology , 82 :883 , 2011
Abstract :
PubMedSearch : Terry_2011_Biochem.Pharmacol_82(8)_883
PubMedID: 21684265

Title : Potentiation of analgesic efficacy but not side effects: co-administration of an alpha4beta2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats - Zhu_2011_Biochem.Pharmacol_82(8)_967
Author(s) : Zhu CZ , Chin CL , Rustay NR , Zhong C , Mikusa J , Chandran P , Salyers A , Gomez E , Simler G , Lewis LG , Gauvin D , Baker S , Pai M , Tovcimak A , Brown J , Komater V , Fox GB , Decker MW , Jacobson PB , Gopalakrishnan M , Lee CH , Honore P
Ref : Biochemical Pharmacology , 82 :967 , 2011
Abstract :
PubMedSearch : Zhu_2011_Biochem.Pharmacol_82(8)_967
PubMedID: 21620806

Title : Pharmacokinetic modeling and [(1)(2)(3)]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing regimen for ABT-089 - Chin_2011_J.Pharmacol.Exp.Ther_336_716
Author(s) : Chin CL , Carr RA , Llano DA , Barret O , Xu H , Batis J , Koren AO , Seibyl JP , Marsh KC , Tamagnan G , Decker MW , Day M , Fox GB
Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :716 , 2011
Abstract :
PubMedSearch : Chin_2011_J.Pharmacol.Exp.Ther_336_716
PubMedID: 21172907

Title : Prefrontal beta2 subunit-containing and alpha7 nicotinic acetylcholine receptors differentially control glutamatergic and cholinergic signaling - Parikh_2010_J.Neurosci_30_3518
Author(s) : Parikh V , Ji J , Decker MW , Sarter M
Ref : Journal of Neuroscience , 30 :3518 , 2010
Abstract :
PubMedSearch : Parikh_2010_J.Neurosci_30_3518
PubMedID: 20203212

Title : In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease - Bitner_2010_J.Pharmacol.Exp.Ther_334_875
Author(s) : Bitner RS , Bunnelle WH , Decker MW , Drescher KU , Kohlhaas KL , Markosyan S , Marsh KC , Nikkel AL , Browman K , Radek R , Anderson DJ , Buccafusco JJ , Gopalakrishnan M
Ref : Journal of Pharmacology & Experimental Therapeutics , 334 :875 , 2010
Abstract :
PubMedSearch : Bitner_2010_J.Pharmacol.Exp.Ther_334_875
PubMedID: 20504913

Title : Poster: Positive allosteric modulation of alpha4\/beta2 nicotinic receptors potentiates some CNS effects of the alpha4\/beta2 agonist, ABT-594 -
Author(s) : Franklin SR , Mohler EG , Komater VA , Robb H , Radek RJ , Rustay NR , Brown JW , Gopalakrishnan M , Decker MW , Rueter LE
Ref : Biochemical Pharmacology , 78 :921 , 2009
PubMedID:

Title : Poster: In vivo characterization of the co-administration of alpha4\/beta2 neuronal nicotinic receptor agonist and positive allosteric modulator in experimental pain in rats -
Author(s) : Zhu CZ , Chin C-l , Zhong C , Mikusa J , Chandran P , Salyers A , Wensink E , Silmer G , Lewis LG , Gauvin D , Baker S , Tovcimak A , Brown J , Rustay N , Fox GB , Decker MW , Lee C-H , Gopalakrishnan M , Honore P
Ref : Biochemical Pharmacology , 78 :920 , 2009
PubMedID:

Title : Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex - Parikh_2008_J.Neurosci_28_3769
Author(s) : Parikh V , Man K , Decker MW , Sarter M
Ref : Journal of Neuroscience , 28 :3769 , 2008
Abstract :
PubMedSearch : Parikh_2008_J.Neurosci_28_3769
PubMedID: 18385335

Title : The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions - Decker_2008_Expert.Opin.Drug.Discov_3_1027
Author(s) : Decker MW , Gopalakrishnan M , Meyer MD
Ref : Expert Opin Drug Discov , 3 :1027 , 2008
Abstract :
PubMedSearch : Decker_2008_Expert.Opin.Drug.Discov_3_1027
PubMedID: 23506178

Title : Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1\/2 and CREB phosphorylation pathways - Bitner_2007_J.Neurosci_27_10578
Author(s) : Bitner RS , Bunnelle WH , Anderson DJ , Briggs CA , Buccafusco JJ , Curzon P , Decker MW , Frost JM , Gronlien JH , Gubbins E , Li J , Malysz J , Markosyan S , Marsh K , Meyer MD , Nikkel AL , Radek RJ , Robb HM , Timmermann DB , Sullivan JP , Gopalakrishnan M
Ref : Journal of Neuroscience , 27 :10578 , 2007
Abstract :
PubMedSearch : Bitner_2007_J.Neurosci_27_10578
PubMedID: 17898229

Title : Neuronal nicotinic receptor agonists for the treatment of attention-deficit\/hyperactivity disorder: focus on cognition - Wilens_2007_Biochem.Pharmacol_74(8)_1212
Author(s) : Wilens TE , Decker MW
Ref : Biochemical Pharmacology , 74 :1212 , 2007
Abstract :
PubMedSearch : Wilens_2007_Biochem.Pharmacol_74(8)_1212
PubMedID: 17689498

Title : Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys - Buccafusco_2007_Biochem.Pharmacol_74(8)_1202
Author(s) : Buccafusco JJ , Terry AV, Jr. , Decker MW , Gopalakrishnan M
Ref : Biochemical Pharmacology , 74 :1202 , 2007
Abstract :
PubMedSearch : Buccafusco_2007_Biochem.Pharmacol_74(8)_1202
PubMedID: 17706609

Title : Alpha4beta2 nicotinic receptor stimulation contributes to the effects of nicotine in the DBA\/2 mouse model of sensory gating - Radek_2006_Psychopharmacology.(Berl)_187_47
Author(s) : Radek RJ , Miner HM , Bratcher NA , Decker MW , Gopalakrishnan M , Bitner RS
Ref : Psychopharmacology (Berl) , 187 :47 , 2006
Abstract :
PubMedSearch : Radek_2006_Psychopharmacology.(Berl)_187_47
PubMedID: 16767415

Title : Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment - Curzon_2006_Neurosci.Lett_410_15
Author(s) : Curzon P , Anderson DJ , Nikkel AL , Fox GB , Gopalakrishnan M , Decker MW , Bitner RS
Ref : Neuroscience Letters , 410 :15 , 2006
Abstract :
PubMedSearch : Curzon_2006_Neurosci.Lett_410_15
PubMedID: 17055644

Title : ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders - Rueter_2004_CNS.Drug.Rev_10_167
Author(s) : Rueter LE , Anderson DJ , Briggs CA , Donnelly-Roberts D , Gintant GA , Gopalakrishnan M , Lin NH , Osinski MA , Reinhart GA , Buckley MJ , Martin RL , McDermott JS , Preusser LC , Seifert TR , Su Z , Cox BF , Decker MW , Sullivan JP
Ref : CNS Drug Rev , 10 :167 , 2004
Abstract :
PubMedSearch : Rueter_2004_CNS.Drug.Rev_10_167
PubMedID: 15179445

Title : In vitro and in vivo effects of an alpha3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide - Adams_2004_Brain.Res.Mol.Brain.Res_129_67
Author(s) : Adams MR , Nikkel AL , Donnelly-Roberts D , Watt AT , Johnston JF , Cowsert LM , Butler M , Kroeger PE , Frost L , Curzon P , Decker MW , Bitner RS
Ref : Brain Research Mol Brain Res , 129 :67 , 2004
Abstract :
PubMedSearch : Adams_2004_Brain.Res.Mol.Brain.Res_129_67
PubMedID: 15469883

Title : Alkaloids from frog skin: the discovery of epibatidine and the potential for developing novel non-opioid analgesics -
Author(s) : Daly JW , Garraffo HM , Spande TF , Decker MW , Sullivan JP , Williams M
Ref : Nat Prod Rep , 17 :131 , 2000
PubMedID: 10821107

Title : Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat - Bitner_2000_Brain.Res_871_66
Author(s) : Bitner RS , Nikkel AL , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Namovic M , Jacobs IC , Meyer MD , Decker MW
Ref : Brain Research , 871 :66 , 2000
Abstract :
PubMedSearch : Bitner_2000_Brain.Res_871_66
PubMedID: 10882784

Title : The identification of novel structural compound classes exhibiting high affinity for neuronal nicotinic acetylcholine receptors and analgesic efficacy in preclinical models of pain - Meyer_2000_Eur.J.Pharmacol_393_171
Author(s) : Meyer MD , Decker MW , Rueter LE , Anderson DJ , Dart MJ , Kim KH , Sullivan JP , Williams M
Ref : European Journal of Pharmacology , 393 :171 , 2000
Abstract :
PubMedSearch : Meyer_2000_Eur.J.Pharmacol_393_171
PubMedID: 10771011

Title : ABT-594 [(R)-5-(2-azetidinylmethoxy)-2-chloropyridine]: a novel, orally effective antinociceptive agent acting via neuronal nicotinic acetylcholine receptors: II. In vivo characterization - Bannon_1998_J.Pharmacol.Exp.Ther_285_787
Author(s) : Bannon AW , Decker MW , Curzon P , Buckley MJ , Kim DJ , Radek RJ , Lynch JK , Wasicak JT , Lin NH , Arnold WH , Holladay MW , Williams M , Arneric SP
Ref : Journal of Pharmacology & Experimental Therapeutics , 285 :787 , 1998
Abstract :
PubMedSearch : Bannon_1998_J.Pharmacol.Exp.Ther_285_787
PubMedID: 9580627

Title : Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice - Decker_1998_Eur.J.Pharmacol_346_23
Author(s) : Decker MW , Bannon AW , Buckley MJ , Kim DJ , Holladay MW , Ryther KB , Lin NH , Wasicak JT , Williams M , Arneric SP
Ref : European Journal of Pharmacology , 346 :23 , 1998
Abstract :
PubMedSearch : Decker_1998_Eur.J.Pharmacol_346_23
PubMedID: 9617748

Title : Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys - Prendergast_1998_Psychopharmacology.(Berl)_136_50
Author(s) : Prendergast MA , Jackson WJ , Terry AV, Jr. , Decker MW , Arneric SP , Buccafusco JJ
Ref : Psychopharmacology (Berl) , 136 :50 , 1998
Abstract :
PubMedSearch : Prendergast_1998_Psychopharmacology.(Berl)_136_50
PubMedID: 9537682

Title : Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice - Holladay_1998_Bioorg.Med.Chem.Lett_8_2797
Author(s) : Holladay MW , Bai H , Li Y , Lin NH , Daanen JF , Ryther KB , Wasicak JT , Kincaid JF , He Y , Hettinger AM , Huang P , Anderson DJ , Bannon AW , Buckley MJ , Campbell JE , Donnelly-Roberts D , Gunther KL , Kim DJ , Kuntzweiler TA , Sullivan JP , Decker MW , Arneric SP
Ref : Bioorganic & Medicinal Chemistry Lett , 8 :2797 , 1998
Abstract :
PubMedSearch : Holladay_1998_Bioorg.Med.Chem.Lett_8_2797
PubMedID: 9873625

Title : Identification and initial structure-activity relationships of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine (ABT-594), a potent, orally active, non-opiate analgesic agent acting via neuronal nicotinic acetylcholine receptors - Holladay_1998_J.Med.Chem_41_407
Author(s) : Holladay MW , Wasicak JT , Lin NH , He Y , Ryther KB , Bannon AW , Buckley MJ , Kim DJ , Decker MW , Anderson DJ , Campbell JE , Kuntzweiler TA , Donnelly-Roberts D , Piattoni-Kaplan M , Briggs CA , Williams M , Arneric SP
Ref : Journal of Medicinal Chemistry , 41 :407 , 1998
Abstract :
PubMedSearch : Holladay_1998_J.Med.Chem_41_407
PubMedID: 9484491

Title : Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors - Bannon_1998_Science_279_77
Author(s) : Bannon AW , Decker MW , Holladay MW , Curzon P , Donnelly-Roberts D , Puttfarcken PS , Bitner RS , Diaz A , Dickenson AH , Porsolt RD , Williams M , Arneric SP
Ref : Science , 279 :77 , 1998
Abstract :
PubMedSearch : Bannon_1998_Science_279_77
PubMedID: 9417028

Title : The role of neuronal nicotinic acetylcholine receptors in antinociception: effects of ABT-594 - Decker_1998_J.Physiol.Paris_92_221
Author(s) : Decker MW , Curzon P , Holladay MW , Nikkel AL , Bitner RS , Bannon AW , Donnelly-Roberts D , Puttfarcken PS , Kuntzweiler TA , Briggs CA , Williams M , Arneric SP
Ref : Journal de Physiologie (Paris) , 92 :221 , 1998
Abstract :
PubMedSearch : Decker_1998_J.Physiol.Paris_92_221
PubMedID: 9789812

Title : Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo - Briggs_1997_Pharmacol.Biochem.Behav_57_231
Author(s) : Briggs CA , Anderson DJ , Brioni JD , Buccafusco JJ , Buckley MJ , Campbell JE , Decker MW , Donnelly-Roberts D , Elliott RL , Gopalakrishnan M , Holladay MW , Hui YH , Jackson WJ , Kim DJ , Marsh KC , O'Neill A , Prendergast MA , Ryther KB , Sullivan JP , Arneric SP
Ref : Pharmacol Biochem Behav , 57 :231 , 1997
Abstract :
PubMedSearch : Briggs_1997_Pharmacol.Biochem.Behav_57_231
PubMedID: 9164577

Title : Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties - Lin_1997_J.Med.Chem_40_385
Author(s) : Lin NH , Gunn DE , Ryther KB , Garvey DS , Donnelly-Roberts D , Decker MW , Brioni JD , Buckley MJ , Rodrigues AD , Marsh KG , Anderson DJ , Buccafusco JJ , Prendergast MA , Sullivan JP , Williams M , Arneric SP , Holladay MW
Ref : Journal of Medicinal Chemistry , 40 :385 , 1997
Abstract :
PubMedSearch : Lin_1997_J.Med.Chem_40_385
PubMedID: 9022806

Title : ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys - Decker_1997_J.Pharmacol.Exp.Ther_283_247
Author(s) : Decker MW , Bannon AW , Curzon P , Gunther KL , Brioni JD , Holladay MW , Lin NH , Li Y , Daanen JF , Buccafusco JJ , Prendergast MA , Jackson WJ , Arneric SP
Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :247 , 1997
Abstract :
PubMedSearch : Decker_1997_J.Pharmacol.Exp.Ther_283_247
PubMedID: 9336330

Title : Cholinergic channel activators: novel opportunities for the treatment of CNS disorders - Sullivan_1995_Proc.West.Pharmacol.Soc_38_127
Author(s) : Sullivan JP , Decker MW , Donnelly-Roberts D , Brioni JD , Bannon AW , Holladay MW , Anderson DJ , Briggs CA , Williams M , Arneric SP
Ref : Proc West Pharmacol Soc , 38 :127 , 1995
Abstract :
PubMedSearch : Sullivan_1995_Proc.West.Pharmacol.Soc_38_127
PubMedID: 7480004

Title : Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties - Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50
Author(s) : Arneric SP , Sullivan JP , Decker MW , Brioni JD , Bannon AW , Briggs CA , Donnelly-Roberts D , Radek RJ , Marsh KC , Kyncl J , Williams M , Buccafusco JJ
Ref : Alzheimer Disease & Associated Disorders , 9 Suppl 2 :50 , 1995
Abstract :
PubMedSearch : Arneric_1995_Alzheimer.Dis.Assoc.Disord_9 Suppl 2_50
PubMedID: 8534424

Title : Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors - Decker_1995_Eur.J.Pharmacol_280_79
Author(s) : Decker MW , Anderson DJ , Brioni JD , Donnelly-Roberts D , Kang CH , O'Neill AB , Piattoni-Kaplan M , Swanson S , Sullivan JP
Ref : European Journal of Pharmacology , 280 :79 , 1995
Abstract :
PubMedSearch : Decker_1995_Eur.J.Pharmacol_280_79
PubMedID: 7498257

Title : Novel isoxazoles which interact with brain cholinergic channel receptors have intrinsic cognitive enhancing and anxiolytic activities -
Author(s) : Garvey DS , Wasicak JT , Decker MW , Brioni JD , Buckley MJ , Sullivan JP , Carrera GM , Holladay MW , Arneric SP , Williams M
Ref : Journal of Medicinal Chemistry , 37 :1055 , 1994
PubMedID: 7909335

Title : (+\/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors - Sullivan_1994_J.Pharmacol.Exp.Ther_271_624
Author(s) : Sullivan JP , Decker MW , Brioni JD , Donnelly-Roberts D , Anderson DJ , Bannon AW , Kang CH , Adams P , Piattoni-Kaplan M , Buckley MJ
Ref : Journal of Pharmacology & Experimental Therapeutics , 271 :624 , 1994
Abstract :
PubMedSearch : Sullivan_1994_J.Pharmacol.Exp.Ther_271_624
PubMedID: 7965777