| Title : Dual soluble epoxide hydrolase inhibitor - farnesoid X receptor agonist interventional treatment attenuates renal inflammation and fibrosis - Khan_2023_Front.Immunol_14_1269261 |
| Author(s) : Khan MAH , Nolan B , Stavniichuk A , Merk D , Imig JD |
| Ref : Front Immunol , 14 :1269261 , 2023 |
| Abstract : |
| PubMedSearch : Khan_2023_Front.Immunol_14_1269261 |
| PubMedID: 38235144 |
| Title : Dual sEH\/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity - Jankiewicz_2021_Front.Pharmacol_12_744776 |
| Author(s) : Jankiewicz WK , Barnett SD , Stavniichuk A , Hwang SH , Hammock BD , Belayet JB , Khan AH , Imig JD |
| Ref : Front Pharmacol , 12 :744776 , 2021 |
| Abstract : |
| PubMedSearch : Jankiewicz_2021_Front.Pharmacol_12_744776 |
| PubMedID: 34955823 |
| Title : Multitarget molecule,PTUPB, to treat diabetic nephropathy in rats - Hye_2021_Br.J.Pharmacol_178_4468 |
| Author(s) : Hye Khan MA , Hwang SH , Barnett SD , Stavniichuk A , Jankiewicz WK , Hammock BD , Imig JD |
| Ref : British Journal of Pharmacology , 178 :4468 , 2021 |
| Abstract : |
| PubMedSearch : Hye_2021_Br.J.Pharmacol_178_4468 |
| PubMedID: 34255857 |
| Title : Epoxylipids and soluble epoxide hydrolase in heart diseases - Imig_2021_Biochem.Pharmacol_195_114866 |
| Author(s) : Imig JD , Cervenka L , Neckar J |
| Ref : Biochemical Pharmacology , 195 :114866 , 2021 |
| Abstract : |
| PubMedSearch : Imig_2021_Biochem.Pharmacol_195_114866 |
| PubMedID: 34863976 |
| Title : Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors - |
| Author(s) : Imig JD , Morisseau C |
| Ref : Front Pharmacol , 11 :598858 , 2020 |
| PubMedID: 33071800 |
| Title : Multi-Target Approaches in Metabolic Syndrome - Lillich_2020_Front.Pharmacol_11_554961 |
| Author(s) : Lillich FF , Imig JD , Proschak E |
| Ref : Front Pharmacol , 11 :554961 , 2020 |
| Abstract : |
| PubMedSearch : Lillich_2020_Front.Pharmacol_11_554961 |
| PubMedID: 33776749 |
| Title : Dual Soluble Epoxide Hydrolase Inhibitor\/PPAR-gamma Agonist Attenuates Renal Fibrosis - Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| Author(s) : Stavniichuk A , Hye Khan MA , Yeboah MM , Chesnik MA , Jankiewicz WK , Hartmann M , Blocher R , Kircher T , Savchuk O , Proschak E , Imig JD |
| Ref : Prostaglandins Other Lipid Mediat , :106472 , 2020 |
| Abstract : |
| PubMedSearch : Stavniichuk_2020_Prostaglandins.Other.Lipid.Mediat__106472 |
| PubMedID: 32569747 |
| Title : Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture - Imig_2020_Hypertension__HYPERTENSIONAHA12013898 |
| Author(s) : Imig JD , Jankiewicz WK , Khan AH |
| Ref : Hypertension , :HYPERTENSIONAHA12013898 , 2020 |
| Abstract : |
| PubMedSearch : Imig_2020_Hypertension__HYPERTENSIONAHA12013898 |
| PubMedID: 32475311 |
| Title : Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats - Vackova_2019_Front.Pharmacol_10_18 |
| Author(s) : Vackova S , Kopkan L , Kikerlova S , Huskova Z , Sadowski J , Kompanowska-Jezierska E , Hammock BD , Imig JD , Taborsky M , Melenovsky V , Cervenka L |
| Ref : Front Pharmacol , 10 :18 , 2019 |
| Abstract : |
| PubMedSearch : Vackova_2019_Front.Pharmacol_10_18 |
| PubMedID: 30728778 |
| Title : A dual farnesoid X receptor\/soluble epoxide hydrolase modulator treats non-alcoholic steatohepatitis in mice - Hye_2019_Biochem.Pharmacol_166_212 |
| Author(s) : Hye Khan MA , Schmidt J , Stavniichuk A , Imig JD , Merk D |
| Ref : Biochemical Pharmacology , 166 :212 , 2019 |
| Abstract : |
| PubMedSearch : Hye_2019_Biochem.Pharmacol_166_212 |
| PubMedID: 31129048 |
| Title : Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5\/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease - Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| Author(s) : Certikova Chabova V , Kujal P , Skaroupkova P , Varnourkova Z , Vackova S , Huskova Z , Kikerlova S , Sadowski J , Kompanowska-Jezierska E , Baranowska I , Hwang SH , Hammock BD , Imig JD , Tesar V , Cervenka L |
| Ref : Kidney Blood Press Res , 43 :329 , 2018 |
| Abstract : |
| PubMedSearch : Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| PubMedID: 29529602 |
| Title : Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula - Kala_2018_Physiol.Res_67_401 |
| Author(s) : Kala P , Sedlakova L , Skaroupkova P , Kopkan L , Vanourkova Z , Taborsky M , Nishiyama A , Hwang SH , Hammock BD , Sadowski J , Melenovsky V , Imig JD , Cervenka L |
| Ref : Physiol Res , 67 :401 , 2018 |
| Abstract : |
| PubMedSearch : Kala_2018_Physiol.Res_67_401 |
| PubMedID: 29527914 |
| Title : Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia - Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| Author(s) : Bettaieb A , Koike S , Hsu MF , Ito Y , Chahed S , Bachaalany S , Gruzdev A , Calvo-Rubio M , Lee KSS , Inceoglu B , Imig JD , Villalba JM , Zeldin DC , Hammock BD , Haj FG |
| Ref : Biochimica & Biophysica Acta , 1861 :2758 , 2017 |
| Abstract : |
| PubMedSearch : Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| PubMedID: 28757338 |
| Title : Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula - Cervenka_2015_Physiol.Res_64_857 |
| Author(s) : Cervenka L , Melenovsky V , Huskova Z , Sporkova A , Burgelova M , Skaroupkova P , Hwang SH , Hammock BD , Imig JD , Sadowski J |
| Ref : Physiol Res , 64 :857 , 2015 |
| Abstract : |
| PubMedSearch : Cervenka_2015_Physiol.Res_64_857 |
| PubMedID: 26047375 |
| Title : Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy - Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| Author(s) : Kim J , Yoon SP , Toews ML , Imig JD , Hwang SH , Hammock BD , Padanilam BJ |
| Ref : American Journal of Physiology Renal Physiol , :ajprenal 00531 2014 , 2014 |
| Abstract : |
| PubMedSearch : Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| PubMedID: 25377915 |
| Title : 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications - Falck_2014_J.Med.Chem_57_6965 |
| Author(s) : Falck JR , Koduru SR , Mohapatra S , Manne R , Atcha KR , Atcha R , Manthati VL , Capdevila JH , Christian S , Imig JD , Campbell WB |
| Ref : Journal of Medicinal Chemistry , 57 :6965 , 2014 |
| Abstract : |
| PubMedSearch : Falck_2014_J.Med.Chem_57_6965 |
| PubMedID: 25119815 |
| Title : Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system - Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| Author(s) : Varcabova S , Huskova Z , Kramer HJ , Hwang SH , Hammock BD , Imig JD , Kitada K , Cervenka L |
| Ref : Clinical & Experimental Pharmacology & Physiology , 40 :273 , 2013 |
| Abstract : |
| PubMedSearch : Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| PubMedID: 23039246 |
| Title : Soluble Epoxide Hydrolase Inhibition Exhibits Antihypertensive Actions Independently of Nitric Oxide in Mice with Renovascular Hypertension - Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| Author(s) : Kopkan L , Huskova Z , Sporkova A , Varcabova S , Honetschlagerova Z , Hwang SH , Tsai HJ , Hammock BD , Imig JD , Kramer HJ , Burgelova M , Vojtiskova A , Kujal P , Vernerova Z , Cervenka L |
| Ref : Kidney Blood Press Res , 35 :595 , 2012 |
| Abstract : |
| PubMedSearch : Kopkan_2012_Kidney.Blood.Press.Res_35_595 |
| PubMedID: 22948718 |
| Title : Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension - Neckar_2012_Clin.Sci.(Lond)_122_513 |
| Author(s) : Neckar J , Kopkan L , Huskova Z , Kolar F , Papousek F , Kramer HJ , Hwang SH , Hammock BD , Imig JD , Maly J , Netuka I , Ostadal B , Cervenka L |
| Ref : Clinical Science (Lond) , 122 :513 , 2012 |
| Abstract : |
| PubMedSearch : Neckar_2012_Clin.Sci.(Lond)_122_513 |
| PubMedID: 22324471 |
| Title : Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension - Honetschlagerova_2011_J.Physiol_589_207 |
| Author(s) : Honetschlagerova Z , Z ZH , Vanourkova Z , Sporkova A , Kramer HJ , Hwang SH , Tsai HJ , Hammock BD , Imig JD , Cervenka L , Kopkan L |
| Ref : The Journal of Physiology , 589 :207 , 2011 |
| Abstract : |
| PubMedSearch : Honetschlagerova_2011_J.Physiol_589_207 |
| PubMedID: 21078594 |
| Title : Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles - Gauthier_2011_Am.J.Physiol.Renal.Physiol_301_F765 |
| Author(s) : Gauthier KM , Olson L , Harder A , Isbell M , Imig JD , Gutterman DD , Falck JR , Campbell WB |
| Ref : American Journal of Physiology Renal Physiol , 301 :F765 , 2011 |
| Abstract : |
| PubMedSearch : Gauthier_2011_Am.J.Physiol.Renal.Physiol_301_F765 |
| PubMedID: 21753077 |
| Title : Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension - Manhiani_2009_Am.J.Physiol.Renal.Physiol_297_F740 |
| Author(s) : Manhiani M , Quigley JE , Knight SF , Tasoobshirazi S , Moore T , Brands MW , Hammock BD , Imig JD |
| Ref : American Journal of Physiology Renal Physiol , 297 :F740 , 2009 |
| Abstract : |
| PubMedSearch : Manhiani_2009_Am.J.Physiol.Renal.Physiol_297_F740 |
| PubMedID: 19553349 |
| Title : Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases - Imig_2009_Nat.Rev.Drug.Discov_8_794 |
| Author(s) : Imig JD , Hammock BD |
| Ref : Nat Rev Drug Discov , 8 :794 , 2009 |
| Abstract : |
| PubMedSearch : Imig_2009_Nat.Rev.Drug.Discov_8_794 |
| PubMedID: 19794443 |
| Title : Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels - Olearczyk_2006_J.Pharmacol.Exp.Ther_318_1307 |
| Author(s) : Olearczyk JJ , Field MB , Kim IH , Morisseau C , Hammock BD , Imig JD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 318 :1307 , 2006 |
| Abstract : |
| PubMedSearch : Olearczyk_2006_J.Pharmacol.Exp.Ther_318_1307 |
| PubMedID: 16772540 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats - Zhao_2005_Am.J.Physiol.Regul.Integr.Comp.Physiol_288_R188 |
| Author(s) : Zhao X , Dey A , Romanko OP , Stepp DW , Wang MH , Zhou Y , Jin L , Pollock JS , Webb RC , Imig JD |
| Ref : American Journal of Physiology Regul Integr Comp Physiol , 288 :R188 , 2005 |
| Abstract : |
| PubMedSearch : Zhao_2005_Am.J.Physiol.Regul.Integr.Comp.Physiol_288_R188 |
| PubMedID: 15345471 |
| Title : Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage - Zhao_2004_J.Am.Soc.Nephrol_15_1244 |
| Author(s) : Zhao X , Yamamoto T , Newman JW , Kim IH , Watanabe T , Hammock BD , Stewart J , Pollock JS , Pollock DM , Imig JD |
| Ref : J Am Soc Nephrol , 15 :1244 , 2004 |
| Abstract : |
| PubMedSearch : Zhao_2004_J.Am.Soc.Nephrol_15_1244 |
| PubMedID: 15100364 |
| Title : Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension - Imig_2002_Hypertension_39_690 |
| Author(s) : Imig JD , Zhao X , Capdevila JH , Morisseau C , Hammock BD |
| Ref : Hypertension , 39 :690 , 2002 |
| Abstract : |
| PubMedSearch : Imig_2002_Hypertension_39_690 |
| PubMedID: 11882632 |