Title : Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain - Singh_2021_ACS.Omega_6_7165 |
Author(s) : Singh N , Barnych B , Wagner KM , Wan D , Morisseau C , Hammock BD |
Ref : ACS Omega , 6 :7165 , 2021 |
Abstract : |
PubMedSearch : Singh_2021_ACS.Omega_6_7165 |
PubMedID: 33748630 |
Title : Development of potent inhibitors of the human microsomal epoxide hydrolase - Barnych_2020_Eur.J.Med.Chem_193_112206 |
Author(s) : Barnych B , Singh N , Negrel S , Zhang Y , Magis D , Roux C , Hua X , Ding Z , Morisseau C , Tantillo DJ , Siegel JB , Hammock BD |
Ref : Eur Journal of Medicinal Chemistry , 193 :112206 , 2020 |
Abstract : |
PubMedSearch : Barnych_2020_Eur.J.Med.Chem_193_112206 |
PubMedID: 32203787 |
Gene_locus related to this paper: human-EPHX1 , mouse-EPHX1 |
Title : N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain - Singh_2020_J.Nat.Prod_83_3689 |
Author(s) : Singh N , Barnych B , Morisseau C , Wagner KM , Wan D , Takeshita A , Pham H , Xu T , Dandekar A , Liu JY , Hammock BD |
Ref : Journal of Natural Products , 83 :3689 , 2020 |
Abstract : |
PubMedSearch : Singh_2020_J.Nat.Prod_83_3689 |
PubMedID: 33320645 |
Title : In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea - Wan_2019_Front.Pharmacol_10_464 |
Author(s) : Wan D , Yang J , McReynolds CB , Barnych B , Wagner KM , Morisseau C , Hwang SH , Sun J , Blocher R , Hammock BD |
Ref : Front Pharmacol , 10 :464 , 2019 |
Abstract : |
PubMedSearch : Wan_2019_Front.Pharmacol_10_464 |
PubMedID: 31143115 |
Title : Orally Available Soluble Epoxide Hydrolase\/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain - Blocher_2018_J.Med.Chem_61_3541 |
Author(s) : Blocher R , Wagner KM , Gopireddy RR , Harris TR , Wu H , Barnych B , Hwang SH , Xiang YK , Proschak E , Morisseau C , Hammock BD |
Ref : Journal of Medicinal Chemistry , 61 :3541 , 2018 |
Abstract : |
PubMedSearch : Blocher_2018_J.Med.Chem_61_3541 |
PubMedID: 29614224 |