Title : Serotonin 5-HT(6) Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease - Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
Author(s) : Wieckowski K , Szalaj N , Gryzlo B , Wichur T , Goral I , Slugocka E , Sniecikowska J , Latacz G , Siwek A , Godyn J , Bucki A , Kolaczkowski M , Wieckowska A |
Ref : Int J Mol Sci , 23 : , 2022 |
Abstract : |
PubMedSearch : Wieckowski_2022_Int.J.Mol.Sci_23_9443 |
PubMedID: 36012707 |
Title : Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT(6) receptor with anti-aggregation properties against amyloid-beta and tau - Wichur_2021_Eur.J.Med.Chem_225_113783 |
Author(s) : Wichur T , Pasieka A , Godyn J , Panek D , Goral I , Latacz G , Honkisz-Orzechowska E , Bucki A , Siwek A , Gluch-Lutwin M , Knez D , Brazzolotto X , Gobec S , Kolaczkowski M , Sabate R , Malawska B , Wieckowska A |
Ref : Eur Journal of Medicinal Chemistry , 225 :113783 , 2021 |
Abstract : |
PubMedSearch : Wichur_2021_Eur.J.Med.Chem_225_113783 |
PubMedID: 34461507 |
Title : Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with beta-amyloid anti-aggregation properties - Wichur_2021_Eur.J.Med.Chem_225_113792 |
Author(s) : Wichur T , Godyn J , Goral I , Latacz G , Bucki A , Siwek A , Gluch-Lutwin M , Mordyl B , Sniecikowska J , Walczak M , Knez D , Jukic M , Salat K , Gobec S , Kolaczkowski M , Malawska B , Brazzolotto X , Wieckowska A |
Ref : Eur Journal of Medicinal Chemistry , 225 :113792 , 2021 |
Abstract : |
PubMedSearch : Wichur_2021_Eur.J.Med.Chem_225_113792 |
PubMedID: 34530376 |
Gene_locus related to this paper: human-BCHE |
Title : Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity - Marcinkowska_2019_Arch.Pharm.(Weinheim)__e1900041 |
Author(s) : Marcinkowska M , Bucki A , Panek D , Siwek A , Fajkis N , Bednarski M , Zygmunt M , Godyn J , Del Rio Valdivieso A , Kotanska M , Kolaczkowski M , Wieckowska A |
Ref : Arch Pharm (Weinheim) , :e1900041 , 2019 |
Abstract : |
PubMedSearch : Marcinkowska_2019_Arch.Pharm.(Weinheim)__e1900041 |
PubMedID: 31162703 |
Title : Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease - Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
Author(s) : Wieckowska A , Wichur T , Godyn J , Bucki A , Marcinkowska M , Siwek A , Wieckowski K , Zareba P , Knez D , Gluch-Lutwin M , Kazek G , Latacz G , Mika K , Kolaczkowski M , Korabecny J , Soukup O , Benkova M , Kiec-Kononowicz K , Gobec S , Malawska B |
Ref : ACS Chem Neurosci , 9 :1195 , 2018 |
Abstract : |
PubMedSearch : Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
PubMedID: 29384656 |
Title : Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation - Wieckowska_2016_Eur.J.Med.Chem_124_63 |
Author(s) : Wieckowska A , Kolaczkowski M , Bucki A , Godyn J , Marcinkowska M , Wieckowski K , Zareba P , Siwek A , Kazek G , Gluch-Lutwin M , Mierzejewski P , Bienkowski P , Sienkiewicz-Jarosz H , Knez D , Wichur T , Gobec S , Malawska B |
Ref : Eur Journal of Medicinal Chemistry , 124 :63 , 2016 |
Abstract : |
PubMedSearch : Wieckowska_2016_Eur.J.Med.Chem_124_63 |
PubMedID: 27560283 |