Malawska B

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Title : Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands - Bajda_2019_Eur.J.Med.Chem_185_111785
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Title : Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives - Jonczyk_2019_Bioorg.Chem_90_103084
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Title : Novel carbamate derivatives as selective butyrylcholinesterase inhibitors - Bajda_2018_Bioorg.Chem_78_29
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Title : Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease - Wieckowska_2018_ACS.Chem.Neurosci_9_1195
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Title : Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents - Panek_2018_Molecules_23_
Author(s) : Panek D , Wieckowska A , Pasieka A , Godyn J , Jonczyk J , Bajda M , Knez D , Gobec S , Malawska B
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Title : Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents - Panek_2018_ACS.Chem.Neurosci_9_1074
Author(s) : Panek D , Wieckowska A , Jonczyk J , Godyn J , Bajda M , Wichur T , Pasieka A , Knez D , Pislar A , Korabecny J , Soukup O , Sepsova V , Sabate R , Kos J , Gobec S , Malawska B
Ref : ACS Chem Neurosci , 9 :1074 , 2018
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Title : Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment - Czarnecka_2017_Bioorg.Chem_72_315
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Ref : Bioorg Chem , 72 :315 , 2017
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Title : Advances toward multifunctional cholinesterase and beta-amyloid aggregation inhibitors - Panek_2017_Future.Med.Chem_9_1835
Author(s) : Panek D , Wichur T , Godyn J , Pasieka A , Malawska B
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Title : Lipophilic properties of anti-Alzheimer's agents determined by micellar electrokinetic chromatography and reversed-phase thin-layer chromatography - Godyn_2017_Electrophoresis_38_1268
Author(s) : Godyn J , Hebda M , Wieckowska A , Wieckowski K , Malawska B , Bajda M
Ref : Electrophoresis , 38 :1268 , 2017
PubMedID: 28169440

Title : Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands - Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140
Author(s) : Lazewska D , Jonczyk J , Bajda M , Szalaj N , Wieckowska A , Panek D , Moore C , Kuder K , Malawska B , Kiec-Kononowicz K
Ref : Bioorganic & Medicinal Chemistry Lett , 26 :4140 , 2016
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Title : Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease - Dgachi_2016_Molecules_21_
Author(s) : Dgachi Y , Bautista-Aguilera OM , Benchekroun M , Martin H , Bonet A , Knez D , Godyn J , Malawska B , Gobec S , Chioua M , Janockova J , Soukup O , Chabchoub F , Marco-Contelles J , Ismaili L
Ref : Molecules , 21 : , 2016
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Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495
Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S
Ref : Sci Rep , 6 :39495 , 2016
PubMedID: 28000737
Gene_locus related to this paper: human-BCHE

Title : Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation - Panek_2016_Eur.J.Med.Chem_125_676
Author(s) : Panek D , Wieckowska A , Wichur T , Bajda M , Godyn J , Jonczyk J , Mika K , Janockova J , Soukup O , Knez D , Korabecny J , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 125 :676 , 2016
PubMedID: 27721153

Title : Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy - Dgachi_2016_Eur.J.Med.Chem_126_576
Author(s) : Dgachi Y , Sokolov O , Luzet V , Godyn J , Panek D , Bonet A , Martin H , Iriepa I , Moraleda I , Garcia-Iriepa C , Janockova J , Richert L , Soukup O , Malawska B , Chabchoub F , Marco-Contelles J , Ismaili L
Ref : Eur Journal of Medicinal Chemistry , 126 :576 , 2016
PubMedID: 27918993

Title : Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Abeta1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy - Dgachi_2016_ChemMedChem_11_1318
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Title : Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT6 receptor antagonists. Design, synthesis and biological evaluation - Wieckowska_2016_Eur.J.Med.Chem_124_63
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Title : Therapeutic strategies for Alzheimer's disease in clinical trials - Godyn_2016_Pharmacol.Rep_68_127
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Title : Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta - Hebda_2016_Molecules_21_
Author(s) : Hebda M , Bajda M , Wieckowska A , Szalaj N , Pasieka A , Panek D , Godyn J , Wichur T , Knez D , Gobec S , Malawska B
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Title : Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease - Bajda_2015_Bioorg.Med.Chem_23_5610
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Title : Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with beta-amyloid anti-aggregation properties and beneficial effects on memory in vivo - Wieckowska_2015_Bioorg.Med.Chem_23_2445
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Title : Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and beta-amyloid aggregation inhibitors with neuroprotective properties - Guzior_2015_Eur.J.Med.Chem_92C_738
Author(s) : Guzior N , Bajda M , Skrok M , Kurpiewska K , Lewinski K , Brus B , Pislar A , Kos J , Gobec S , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 92C :738 , 2015
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Title : Multiple Ligands Targeting Cholinesterases and beta-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore - Szalaj_2015_Arch.Pharm.(Weinheim)_348_556
Author(s) : Szalaj N , Bajda M , Dudek K , Brus B , Gobec S , Malawska B
Ref : Arch Pharm (Weinheim) , 348 :556 , 2015
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Title : Isoindoline-1,3-dione derivatives targeting cholinesterases: Design, synthesis and biological evaluation of potential anti-Alzheimer's agents - Guzior_2015_Bioorg.Med.Chem_23_1629
Author(s) : Guzior N , Bajda M , Rakoczy J , Brus B , Gobec S , Malawska B
Ref : Bioorganic & Medicinal Chemistry , 23 :1629 , 2015
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Title : SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD - Bajda_2015_Acta.Pol.Pharm_72_737
Author(s) : Bajda M , Panek D , Hebda M , Wieckowska A , Guzior N , Malawska B
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Title : Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease - Guzior_2015_Curr.Med.Chem_22_373
Author(s) : Guzior N , Wieckowska A , Panek D , Malawska B
Ref : Curr Med Chem , 22 :373 , 2015
PubMedID: 25386820

Title : New tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis - Szymanski_2013_Molecules_18_2878
Author(s) : Szymanski P , Skibinski R , Inglot T , Bajda M , Jonczyk J , Malawska B , Mikiciuk-Olasik E
Ref : Molecules , 18 :2878 , 2013
PubMedID: 23459299

Title : Structure-based search for new inhibitors of cholinesterases - Bajda_2013_Int.J.Mol.Sci_14_5608
Author(s) : Bajda M , Wieckowska A , Hebda M , Guzior N , Sotriffer CA , Malawska B
Ref : Int J Mol Sci , 14 :5608 , 2013
PubMedID: 23478436

Title : Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors - Ignasik_2012_Arch.Pharm.(Weinheim)_345_509
Author(s) : Ignasik M , Bajda M , Guzior N , Prinz M , Holzgrabe U , Malawska B
Ref : Arch Pharm (Weinheim) , 345 :509 , 2012
PubMedID: 22467516

Title : Synthesis, biological activity and molecular modeling of 4-fluoro-N-[omega-(1,2,3,4-tetrahydroacridin-9-ylamino)-alkyl]-benzamide derivatives as cholinesterase inhibitors - Szymanski_2012_Arzneimittelforschung_62_655
Author(s) : Szymanski P , Markowicz M , Bajda M , Malawska B , Mikiciuk-Olasik E
Ref : Arzneimittelforschung , 62 :655 , 2012
PubMedID: 23154886

Title : 2,3-dihydro-1H-cyclopenta[b]quinoline derivatives as acetylcholinesterase inhibitors-synthesis, radiolabeling and biodistribution - Szymanski_2012_Int.J.Mol.Sci_13_10067
Author(s) : Szymanski P , Laznickova A , Laznicek M , Bajda M , Malawska B , Markowicz M , Mikiciuk-Olasik E
Ref : Int J Mol Sci , 13 :10067 , 2012
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Title : Multi-target-directed ligands in Alzheimer's disease treatment - Bajda_2011_Curr.Med.Chem_18_4949
Author(s) : Bajda M , Guzior N , Ignasik M , Malawska B
Ref : Curr Med Chem , 18 :4949 , 2011
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Title : Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors - Wieckowska_2010_Eur.J.Med.Chem_45_5602
Author(s) : Wieckowska A , Bajda M , Guzior N , Malawska B
Ref : Eur Journal of Medicinal Chemistry , 45 :5602 , 2010
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Title : Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors - Bajda_2009_Acta.Pol.Pharm_66_357
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Title : Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment - Musial_2007_Curr.Med.Chem_14_2654
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Title : Synthesis of novel N-alkyl carbamates of a-substituted amides of g-hydroxybutyric acid as potential acetylcholinesterase inhibitors - Musial_2004_Acta.Pol.Pharm_61 Suppl_94
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