| Title : Discovery of New Highly Potent Histamine H(3) Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors - Malek_2024_ACS.Chem.Neurosci__ |
| Author(s) : Malek R , Salat K , Totoson P , Karcz T , Refouvelet B , Skrzypczak-Wiercioch A , Maj M , Simakov A , Martin H , Siwek A , Szalaj N , Godyn J , Panek D , Wieckowska A , Jozwiak K , Demougeot C , Kiec-Kononowicz K , Chabchoub F , Iriepa I , Marco-Contelles J , Ismaili L |
| Ref : ACS Chem Neurosci , : , 2024 |
| Abstract : |
| PubMedSearch : Malek_2024_ACS.Chem.Neurosci__ |
| PubMedID: 39208251 |
| Title : Multitargeting Histamine H(3) Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives - Lazewska_2023_Molecules_28_ |
| Author(s) : Lazewska D , Kaleta M , Zareba P , Godyn J , Dubiel M , Honkisz-Orzechowska E , Doroz-Plonka A , Wieckowska A , Stark H , Kiec-Kononowicz K |
| Ref : Molecules , 28 : , 2023 |
| Abstract : |
| PubMedSearch : Lazewska_2023_Molecules_28_ |
| PubMedID: 36903593 |
| Title : Benzophenone Derivatives with Histamine H(3) Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease - Godyn_2022_Molecules_28_ |
| Author(s) : Godyn J , Zareba P , Stary D , Kaleta M , Kuder KJ , Latacz G , Mogilski S , Reiner-Link D , Frank A , Doroz-Plonka A , Olejarz-Maciej A , Sudol-Talaj S , Nolte T , Handzlik J , Stark H , Wieckowska A , Malawska B , Kiec-Kononowicz K , Lazewska D , Bajda M |
| Ref : Molecules , 28 : , 2022 |
| Abstract : |
| PubMedSearch : Godyn_2022_Molecules_28_ |
| PubMedID: 36615435 |
| Title : Biphenylalkoxyamine Derivatives-Histamine H(3) Receptor Ligands with Butyrylcholinesterase Inhibitory Activity - Lazewska_2021_Molecules_26_ |
| Author(s) : Lazewska D , Zareba P , Godyn J , Doroz-Plonka A , Frank A , Reiner-Link D , Bajda M , Stary D , Mogilski S , Olejarz-Maciej A , Kaleta M , Stark H , Malawska B , Kiec-Kononowicz K |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Lazewska_2021_Molecules_26_ |
| PubMedID: 34208297 |
| Title : Cyanobiphenyls: Novel H(3) receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease - Godyn_2021_Bioorg.Chem_114_105129 |
| Author(s) : Godyn J , Zareba P , aewska D , Stary D , Reiner-Link D , Frank A , Latacz G , Mogilski S , Kaleta M , Doroz-Plonka A , Lubelska A , Honkisz-Orzechowska E , Olejarz-Maciej A , Handzlik J , Stark H , Kiec-Kononowicz K , Malawska B , Bajda M |
| Ref : Bioorg Chem , 114 :105129 , 2021 |
| Abstract : |
| PubMedSearch : Godyn_2021_Bioorg.Chem_114_105129 |
| PubMedID: 34217977 |
| Title : Rational design of new multitarget histamine H(3) receptor ligands as potential candidates for treatment of Alzheimer's disease - Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| Author(s) : Lazewska D , Bajda M , Kaleta M , Zareba P , Doroz-Plonka A , Siwek A , Alachkar A , Mogilski S , Saad A , Kuder K , Olejarz-Maciej A , Godyn J , Stary D , Sudol S , Wiecek M , Latacz G , Walczak M , Handzlik J , Sadek B , Malawska B , Kiec-Kononowicz K |
| Ref : Eur Journal of Medicinal Chemistry , 207 :112743 , 2020 |
| Abstract : |
| PubMedSearch : Lazewska_2020_Eur.J.Med.Chem_207_112743 |
| PubMedID: 32882609 |
| Title : Simultaneous Blockade of Histamine H(3) Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf\/J Mouse Model of Autism - Eissa_2020_Biomolecules_10_ |
| Author(s) : Eissa N , Jayaprakash P , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B |
| Ref : Biomolecules , 10 : , 2020 |
| Abstract : |
| PubMedSearch : Eissa_2020_Biomolecules_10_ |
| PubMedID: 32872194 |
| Title : The Dual-Active Histamine H3 Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice - Eissa_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Eissa N , Azimullah S , Jayaprakash P , Jayaraj RL , Reiner D , Ojha SK , Beiram R , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : |
| PubMedSearch : Eissa_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 32503208 |
| Title : The dual-active histamine H3 receptor antagonist and acetylcholine esterase inhibitor E100 ameliorates stereotyped repetitive behavior and neuroinflammation in sodium valproate induced autism in mice - Eissa_2019_Chem.Biol.Interact__108775 |
| Author(s) : Eissa N , Azimullah S , Jayaprakash P , Jayaraj RL , Reiner D , Ojha SK , Beiram R , Stark H , Lazewska D , Kiec-Kononowicz K , Sadek B |
| Ref : Chemico-Biological Interactions , :108775 , 2019 |
| Abstract : |
| PubMedSearch : Eissa_2019_Chem.Biol.Interact__108775 |
| PubMedID: 31369746 |
| Title : Search for new multi-target compounds against Alzheimer's disease among histamine H3 receptor ligands - Bajda_2019_Eur.J.Med.Chem_185_111785 |
| Author(s) : Bajda M , Lazewska D , Godyn J , Zareba P , Kuder K , Hagenow S , Latka K , Stawarska E , Stark H , Kiec-Kononowicz K , Malawska B |
| Ref : Eur Journal of Medicinal Chemistry , 185 :111785 , 2019 |
| Abstract : |
| PubMedSearch : Bajda_2019_Eur.J.Med.Chem_185_111785 |
| PubMedID: 31669851 |
| Title : New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition - Malek_2019_J.Med.Chem_62_11416 |
| Author(s) : Malek R , Arribas RL , Palomino-Antolin A , Totoson P , Demougeot C , Kobrlova T , Soukup O , Iriepa I , Moraleda I , Diez-Iriepa D , Godyn J , Panek D , Malawska B , Gluch-Lutwin M , Mordyl B , Siwek A , Chabchoub F , Marco-Contelles J , Kiec-Kononowicz K , Egea J , de los Rios C , Ismaili L |
| Ref : Journal of Medicinal Chemistry , 62 :11416 , 2019 |
| Abstract : |
| PubMedSearch : Malek_2019_J.Med.Chem_62_11416 |
| PubMedID: 31724859 |
| Title : Novel Multitarget-Directed Ligands Aiming at Symptoms and Causes of Alzheimer's Disease - Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| Author(s) : Wieckowska A , Wichur T , Godyn J , Bucki A , Marcinkowska M , Siwek A , Wieckowski K , Zareba P , Knez D , Gluch-Lutwin M , Kazek G , Latacz G , Mika K , Kolaczkowski M , Korabecny J , Soukup O , Benkova M , Kiec-Kononowicz K , Gobec S , Malawska B |
| Ref : ACS Chem Neurosci , 9 :1195 , 2018 |
| Abstract : |
| PubMedSearch : Wieckowska_2018_ACS.Chem.Neurosci_9_1195 |
| PubMedID: 29384656 |
| Title : Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands - Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| Author(s) : Lazewska D , Jonczyk J , Bajda M , Szalaj N , Wieckowska A , Panek D , Moore C , Kuder K , Malawska B , Kiec-Kononowicz K |
| Ref : Bioorganic & Medicinal Chemistry Lett , 26 :4140 , 2016 |
| Abstract : |
| PubMedSearch : Lazewska_2016_Bioorg.Med.Chem.Lett_26_4140 |
| PubMedID: 27445168 |